Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Andrew, Giovanni"'
Publikováno v:
In Procedia Computer Science 2023 227:398-405
Foreign aid is publicly motivated by a moral obligation to help the poor and develop underdeveloped countries. Donors have invested more than US$2.3 trillion in foreign aid, but despite this significant investment, 3 billion people are still living o
Externí odkaz:
http://hdl.handle.net/10500/5689
Autor:
Tsuyoshi Hirota, May Hui, David A. Prober, Suna Li, Eric A. Mosser, Steve A. Kay, Chanpreet Singh, Amy Wang, Andrew Giovanni, Cindy N. Chiu, T. Katherine Tamai
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
The circadian clock ensures that behavioral and physiological processes occur at appropriate times during the 24-hour day/night cycle, and is regulated at both the cellular and organismal levels. To identify pathways acting on intact animals, we perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a3bb094b0c445f8816ddd330e67e6f
https://pubmed.ncbi.nlm.nih.gov/31455847
https://pubmed.ncbi.nlm.nih.gov/31455847
Autor:
Ramalinga Dharanipragada, John Hoekman, Xiaoyou Ying, Hsiao-Ying Wey, Jacob M. Hooker, Kyle C. Van de Bittner, Genevieve C. Van de Bittner, Wayne Rowe, Kim Alving, Andrew Giovanni, Anurag Gupta, William J Hurst
Publikováno v:
ACS chemical neuroscience. 9(2)
Intranasal drug delivery is a noninvasive drug delivery route that can enhance systemic delivery of therapeutics with poor oral bioavailability by exploiting the rich microvasculature within the nasal cavity. The intranasal delivery route has also be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f336ec7d81e40b55cd3884c43d6c94b0
https://pubmed.ncbi.nlm.nih.gov/29035509
https://pubmed.ncbi.nlm.nih.gov/29035509
Publikováno v:
Journal of Developing Societies. 30:195-221
Foreign aid is publicly motivated by a moral obligation to help the poor and develop underdeveloped countries. Despite the vast amount of foreign aid spent annually to address the poverty of millions of people and the economic decline of underdevelop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::142ee4b55a6828e6554ed0fd91fd3d23
https://doi.org/10.1177/0169796x14525527
https://doi.org/10.1177/0169796x14525527
Autor:
Kent W. Neuenschwander, Anthony C. Scotese, Larry Davis, Joachim E. Roehr, Shannon Dwyer, Neil Moorcroft, Zhongli Gao, Andrew Giovanni
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:1498-1501
A series of tetrahydroisoquinolines were designed, synthesized and evaluated as the first non-natural product type of compounds with dual D1 receptor (D1R) agonism and D2 receptor (D2R) antagonism properties for treatment of schizophrenia. The initia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88f3a68c194c193169d93c944ef86205
https://doi.org/10.1016/j.bmcl.2012.12.046
https://doi.org/10.1016/j.bmcl.2012.12.046
Publikováno v:
Neurobiology of Aging. 21:771-781
Excitotoxic stress is potentially an important component of disorders such as stroke and neurodegenerative diseases. Its toxic effects appear to be transduced through mechanisms that result in both acute and delayed forms of death. We examined here w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9abcfc9f9bf494ee589df7dafdae1b98
https://doi.org/10.1016/s0197-4580(00)00220-7
https://doi.org/10.1016/s0197-4580(00)00220-7
Autor:
Ruth S. Slack, George S. Robertson, David S. Park, Michael J. O'Hare, Andrew Giovanni, Nicholas J. Dyson, Erick J. Morris, Elizabeth Keramaris, Sheng T. Hou
Publikováno v:
Journal of Biological Chemistry. 275:11553-11560
Although B-amyloid (AB) is suggested to play an important role in Alzheimer's disease, the mechanisms that control AB-evoked toxicity are unclear. We demonstrated previously that the cell cycle-related cyclin-dependent kinase 4/6/retinoblastoma prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b192160b60b1ac1d38704b60a3c81c3d
https://doi.org/10.1074/jbc.275.16.11553
https://doi.org/10.1074/jbc.275.16.11553
Publikováno v:
Journal of Biological Chemistry. 274:19011-19016
Previous evidence by others has indicated that a variety of cell cycle-related molecules are up-regulated in brains of Alzheimer's disease patients. The significance of this increase, however, is unclear. Accordingly, we examined the obligate nature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1f6a7e92aa18f6b5af36250269d840
https://doi.org/10.1074/jbc.274.27.19011
https://doi.org/10.1074/jbc.274.27.19011
Publikováno v:
Behavioural Brain Research. 78:211-223
The effect of neonatal hippocampal lesions on behavioral sensitivity to amphetamine (AMPH) and dopamine (DA) release in the nucleus accumbens (NAc) were examined. The ventral hippocampus was damaged bilaterally by ibotenic acid on postnatal day 7 (PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c8b316f3ea4dd471ad57a2dfd711c6
https://doi.org/10.1016/0166-4328(95)00251-0
https://doi.org/10.1016/0166-4328(95)00251-0