Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Andrew, Emley"'
Autor:
April Deng, Andrew Emley, Shi Yang, Joanna E Richards, Mai P. Hoang, Jungeun Lee, Daniel D. Miller, Meera Mahalingam
Publikováno v:
Modern Pathology. 25:505-515
Desmoplastic melanoma is subclassified into pure and mixed variants with a higher rate of lymph node metastasis in the latter. Given that reasons for these biological differences are not currently known, we investigated these subtypes with techniques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b093f58b3d52ce7eb39cdfab5629e33
https://doi.org/10.1038/modpathol.2011.196
https://doi.org/10.1038/modpathol.2011.196
Publikováno v:
The American Journal of Dermatopathology. 33:1-16
Advances made within the field of genomics and proteomics have facilitated the emergence of a new era of molecular diagnostics. However, ongoing rapid developments in molecular methodology ensure that this remains a complex field, accessible primaril
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b5aee6c66094bc392020322c4c9da0
https://doi.org/10.1097/dad.0b013e3181d7a2c0
https://doi.org/10.1097/dad.0b013e3181d7a2c0
Publikováno v:
Journal of Cutaneous Pathology. 37:344-349
Rare reports indicate that the frequency of BRAFV600E mutations is high in atypical Spitz nevi. The purpose of this study was to ascertain the utility of the RAF/RAS mutational status as a diagnostic adjunct in lesions with histologic features that d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063b9c23e6f9bbe0ecfbfcec2c243d9d
https://doi.org/10.1111/j.1600-0560.2009.01433.x
https://doi.org/10.1111/j.1600-0560.2009.01433.x
Publikováno v:
British Journal of Dermatology. 162:677-680
First described by Clark et al., atypical genital naevi (AGN) are a relatively uncommon subset of clinically benign naevi of the genitalia or perineum that exhibit atypical histological features.1,2 Similar lesions have subsequently been described al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20c8458d7cd5fee216c0ed02538dddc7
https://doi.org/10.1111/j.1365-2133.2009.09558.x
https://doi.org/10.1111/j.1365-2133.2009.09558.x
Autor:
Shaillay Kumar Dogra, J-Ae Richards, Phyu P. Aung, Meera Mahalingam, Andrew Emley, Narendra Wajapeyee, Romi Gupta, Yuying Dong, Y Kluger
Publikováno v:
Oncogene. 33(38)
Cancer cells acquire several traits that allow for their survival and progression, including the ability to evade the host immune response. However, the mechanisms by which cancer cells evade host immune responses remain largely elusive. Here we stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762ba5fdd33db55d9456ce4b2798e2ac
https://pubmed.ncbi.nlm.nih.gov/24141770
https://pubmed.ncbi.nlm.nih.gov/24141770
Publikováno v:
The American Journal of dermatopathology. 34(1)
BACKGROUND Given the correlation between KIT mutations and immunohistochemical expression of CKIT in acral melanoma, our aim was to confirm the utility of CKIT detection as a screening tool for KIT genotyping in atypical acral nevi and to ascertain t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6725db959029d574017796e493252fb
https://pubmed.ncbi.nlm.nih.gov/22094233
https://pubmed.ncbi.nlm.nih.gov/22094233
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 755
Laser microdissection is a nonmolecular, minimally disruptive method to obtain cytologically and/or phenotypically defined cells or groups of cells from heterogeneous tissues. It is a versatile technology and allows the preparation of homogenous isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b923f4eff8afc6f3a314dde7e7a62c6e
https://pubmed.ncbi.nlm.nih.gov/21761290
https://pubmed.ncbi.nlm.nih.gov/21761290
Publikováno v:
Methods in Molecular Biology ISBN: 9781617791628
Laser microdissection is a nonmolecular, minimally disruptive method to obtain cytologically and/or phenotypically defined cells or groups of cells from heterogeneous tissues. It is a versatile technology and allows the preparation of homogenous isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7cb8dc76825c55548df57c92689be15
https://doi.org/10.1007/978-1-61779-163-5_1
https://doi.org/10.1007/978-1-61779-163-5_1
Publikováno v:
Human pathology. 42(1)
A recent study indicates that somatic mutations in codon 209 of GNAQ, a gene encoding the signaling protein G-protein α subunit q, may be present in up to 80% of blue nevi. Given that mutations in GNAQ represent dominant dark skin (Dsk) mutations ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a142c58afd909fe95d09c9cc5aea1d
https://pubmed.ncbi.nlm.nih.gov/21056896
https://pubmed.ncbi.nlm.nih.gov/21056896
Autor:
Shi Yang, Michael R. Green, Narendra Wajapeyee, Andrew Emley, Meera Mahalingam, Kristen DeCarlo
Publikováno v:
Human pathology. 41(6)
Oncogenic BRAF as an early and fundamental feature of melanocytic neoplasia has been confirmed with its identification in both melanoma and nevi. Oncogenic BRAF has been shown to induce senescence/apoptosis by up-regulating the tumor suppressor IGFBP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f514cda35b15c98185a9bd76decc927a
https://pubmed.ncbi.nlm.nih.gov/20233623
https://pubmed.ncbi.nlm.nih.gov/20233623