Zobrazeno 1 - 10
of 717
pro vyhledávání: '"Andrew, Chan"'
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-23 (2024)
Abstract Multiple sclerosis (MS) is a complex chronic neuroinflammatory disease characterized by demyelination leading to neuronal dysfunction and neurodegeneration manifested by various neurological impairments. The endocannabinoid system (ECS) is a
Externí odkaz:
https://doaj.org/article/70ef30f046d84a22a347e1e78698a250
Autor:
Sneha Vishwanath, George William Carnell, Martina Billmeier, Luis Ohlendorf, Patrick Neckermann, Benedikt Asbach, Charlotte George, Maria Suau Sans, Andrew Chan, Joey Olivier, Angalee Nadesalingam, Sebastian Einhauser, Nigel Temperton, Diego Cantoni, Joe Grove, Ingo Jordan, Volker Sandig, Paul Tonks, Johannes Geiger, Christian Dohmen, Verena Mummert, Anne Rosalind Samuel, Christian Plank, Rebecca Kinsley, Ralf Wagner, Jonathan Luke Heeney
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-9 (2024)
Abstract Updates of SARS-CoV-2 vaccines are required to generate immunity in the population against constantly evolving SARS-CoV-2 variants of concerns (VOCs). Here we describe three novel in-silico designed spike-based antigens capable of inducing n
Externí odkaz:
https://doaj.org/article/82ef274560d34dc98c35687c198efcf5
Autor:
Madeleine Wiebe, Marnie Mackay, Ragur Krishnan, Julie Tian, Jakob Larsson, Setayesh Modanloo, Christiane Job McIntosh, Melissa Sztym, Gail Elton-Smith, Alyssa Rose, Chester Ho, Andrew Greenshaw, Bo Cao, Andrew Chan, Jake Hayward
Publikováno v:
PLOS Digital Health, Vol 3, Iss 8, p e0000571 (2024)
IntroductionCommon, consumer-grade biosensors mounted on fitness trackers and smartwatches can measure an array of biometrics that have potential utility in post-discharge medical monitoring, especially in remote/rural communities. The feasibility ch
Externí odkaz:
https://doaj.org/article/2ed7fe21c3544d61a51503a50d675401
Autor:
Rachel Sze Jen Goh, Bryan Chong, Jayanth Jayabaskaran, Silingga Metta Jauhari, Siew Pang Chan, Martin Tze Wah Kueh, Kannan Shankar, Henry Li, Yip Han Chin, Gwyneth Kong, Vickram Vijay Anand, Keith Andrew Chan, Indah Sukmawati, Sue Anne Toh, Mark Muthiah, Jiong-Wei Wang, Gary Tse, Anurag Mehta, Alan Fong, Lohendran Baskaran, Liang Zhong, Jonathan Yap, Khung Keong Yeo, Derek J. Hausenloy, Jack Wei Chieh Tan, Tze-Fan Chao, Yi-Heng Li, Shir Lynn Lim, Koo Hui Chan, Poay Huan Loh, Ping Chai, Tiong Cheng Yeo, Adrian F. Low, Chi Hang Lee, Roger Foo, Huay Cheem Tan, James Yip, Sarita Rao, Satoshi Honda, Satoshi Yasuda, Takashi Kajiya, Shinya Goto, Bryan P. Yan, Xin Zhou, Gemma A. Figtree, Mamas A. Mamas, Yongcheol Kim, Young-Hoon Jeong, Moo Hyun Kim, Duk-Woo Park, Seung-Jung Park, A Mark Richards, Mark Y. Chan, Gregory Y.H. Lip, Nicholas W.S. Chew
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 49, Iss , Pp 101138- (2024)
Summary: Background: Given the rapidly growing burden of cardiovascular disease (CVD) in Asia, this study forecasts the CVD burden and associated risk factors in Asia from 2025 to 2050. Methods: Data from the Global Burden of Disease 2019 study was u
Externí odkaz:
https://doaj.org/article/29d35691046b4033a58936d0dff81628
Autor:
Matthias Schwab, Andrew Chan, Anna-Katharina Eser, Boris Kallmann, Dieter Pöhlau, Joachim Richter, Torsten B. Wagner, Christoph Grothe
Publikováno v:
Neurology and Therapy, Vol 13, Iss 3, Pp 641-653 (2024)
Abstract Introduction Treatment adherence is a critical success factor in the disease-modifying therapy (DMT) of multiple sclerosis (MS). The REBISTART study prospectively evaluated adherence in patients using components of a patient support program
Externí odkaz:
https://doaj.org/article/37e20567ddba4394b0fa4dbb255d5e11
Autor:
Aleksandra Olszewska, Jiajing Duan, Jana Javorovic, K. L. Andrew Chan, James Rickard, Simon Pitchford, Ben Forbes
Publikováno v:
Gels, Vol 10, Iss 9, p 572 (2024)
This observational study reports the process for the manufacture of RAPIDTM Biodynamic Haematogel and explores the properties of the platelet and leukocyte-rich plasma gels formed. Gels were manufactured from 60 mL of human blood using the protocol o
Externí odkaz:
https://doaj.org/article/81bcfe42797e47288a6d2a98e44f3ffc
Autor:
Michael Graber, Alice Panchaud, Helene Legardeur, Tobias Derfuss, Christoph Friedli, Claudio Gobbi, Chiara Zecca, Cristina Granziera, Ilijas Jelcic, Helly Noemi Hammer, Sandra Bigi, Lara Diem, Nicole Kamber, Veronika Kana, Jens Kuhle, Stefanie Müller, Anke Salmen, Robert Hoepner, Philipp Do Canto, Marie Théaudin, Daniel Surbek, Caroline Pot, Andrew Chan
Publikováno v:
Clinical and Translational Neuroscience, Vol 8, Iss 3, p 26 (2024)
A large number of disease-modifying immunotherapies are available for the treatment of people with multiple sclerosis. Many disease-modifying immunotherapies show scarce or no safety data in pregnancy and breastfeeding and are labeled as being contra
Externí odkaz:
https://doaj.org/article/86372ba7025c406cb56b08a023c68ebc
Autor:
Martina Greselin, Po-Jui Lu, Lester Melie-Garcia, Mario Ocampo-Pineda, Riccardo Galbusera, Alessandro Cagol, Matthias Weigel, Nina de Oliveira Siebenborn, Esther Ruberte, Pascal Benkert, Stefanie Müller, Sebastian Finkener, Jochen Vehoff, Giulio Disanto, Oliver Findling, Andrew Chan, Anke Salmen, Caroline Pot, Claire Bridel, Chiara Zecca, Tobias Derfuss, Johanna M. Lieb, Michael Diepers, Franca Wagner, Maria I. Vargas, Renaud Du Pasquier, Patrice H. Lalive, Emanuele Pravatà, Johannes Weber, Claudio Gobbi, David Leppert, Olaf Chan-Hi Kim, Philippe C. Cattin, Robert Hoepner, Patrick Roth, Ludwig Kappos, Jens Kuhle, Cristina Granziera
Publikováno v:
Bioengineering, Vol 11, Iss 8, p 858 (2024)
The detection of contrast-enhancing lesions (CELs) is fundamental for the diagnosis and monitoring of patients with multiple sclerosis (MS). This task is time-consuming and suffers from high intra- and inter-rater variability in clinical practice. Ho
Externí odkaz:
https://doaj.org/article/753b7b7b06c042a89d9dbeabe7219d4d
Autor:
Christoph Friedli, Nik Krajnc, Helly N. Hammer, Stefanie Marti, Tobias Zrzavy, Maria E. Evangelopoulos, Ioanna Kapsali, Paulus Rommer, Thomas Berger, Andrew Chan, Gabriel Bsteh, Robert Hoepner
Publikováno v:
Journal of Central Nervous System Disease, Vol 16 (2024)
Introduction Patients with Multiple Sclerosis (pwMS) treated with anti-CD20 (cluster of differentiation) monoclonal antibodies (mAbs) such as ocrelizumab (OCR) and ofatumumab (OFA) show a reduction mainly of B-lymphocytes, but also other lymphocyte s
Externí odkaz:
https://doaj.org/article/f71d643750d84c1694bf98728b6a6655
Autor:
Magnus Jensen, Shiyue Liu, Elzbieta Stepula, Davide Martella, Anahid A. Birjandi, Keith Farrell‐Dillon, Ka Lung Andrew Chan, Maddy Parsons, Ciro Chiappini, Sarah J. Chapple, Giovanni E. Mann, Tom Vercauteren, Vincenzo Abbate, Mads S. Bergholt
Publikováno v:
Advanced Science, Vol 11, Iss 14, Pp n/a-n/a (2024)
Abstract Lipid metabolism and signaling play pivotal functions in biology and disease development. Despite this, currently available optical techniques are limited in their ability to directly visualize the lipidome in tissues. In this study, opto‐
Externí odkaz:
https://doaj.org/article/6c00e459bee24bc39260a84dd801ad2b