Zobrazeno 1 - 10
of 318
pro vyhledávání: '"Andrew, Arnold"'
Publikováno v:
Endocrine Connections, Vol 10, Iss 3, Pp 302-308 (2021)
Objective: Primary hyperparathyroidism is most often caused by a sporadic single-gland parathyroid adenoma (PTA), a tumor type for which cyclin D1 is the only known and experimentally validated oncoprotein. However, the molecular origins of its frequ
Externí odkaz:
https://doaj.org/article/3bb003b2317744b4a43315debcc9b2f8
Autor:
Oliver Lyons, James Walker, Christopher Seet, Mohammed Ikram, Adam Kuchta, Andrew Arnold, Magda Hernández-Vásquez, Maike Frye, Gema Vizcay-Barrena, Roland A. Fleck, Ashish S. Patel, Soundrie Padayachee, Peter Mortimer, Steve Jeffery, Siren Berland, Sahar Mansour, Pia Ostergaard, Taija Makinen, Bijan Modarai, Prakash Saha, Alberto Smith
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
Venous valve (VV) failure causes chronic venous insufficiency, but the molecular regulation of valve development is poorly understood. A primary lymphatic anomaly, caused by mutations in the receptor tyrosine kinase EPHB4, was recently described, wit
Externí odkaz:
https://doaj.org/article/ec0695e085a24322bfff5ed5770002cf
Autor:
Aaliyah Riccardi, Carolina Lemos, Ryan Ramos, Justin Bellizzi, Kourosh Parham, Taylor C. Brown, Reju Korah, Tobias Carling, Jessica Costa‐Guda, Andrew Arnold
Publikováno v:
JBMR Plus, Vol 4, Iss 6, Pp n/a-n/a (2020)
ABSTRACT Benign parathyroid adenoma is the most common cause of primary hyperparathyroidism, whereas malignant parathyroid carcinoma is exceedingly rare. Distinguishing parathyroid carcinoma from benign adenoma is often difficult, and may be consider
Externí odkaz:
https://doaj.org/article/c7962ed2affb4b2187f0efcef6543067
Autor:
Huan Wang, Aaron Bender, Peng Wang, Esra Karakose, William B. Inabnet, Steven K. Libutti, Andrew Arnold, Luca Lambertini, Micheal Stang, Herbert Chen, Yumi Kasai, Milind Mahajan, Yayoi Kinoshita, Gustavo Fernandez-Ranvier, Thomas C. Becker, Karen K. Takane, Laura A. Walker, Shira Saul, Rong Chen, Donald K. Scott, Jorge Ferrer, Yevgeniy Antipin, Michael Donovan, Andrew V. Uzilov, Boris Reva, Eric E. Schadt, Bojan Losic, Carmen Argmann, Andrew F. Stewart
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Diabetes results in part from a deficiency of functional pancreatic beta cells. Here, the authors study the genomic and epigenetic landscapes of human insulinomas to gain insight into possible pathways for therapeutic beta cell regeneration, highligh
Externí odkaz:
https://doaj.org/article/80c3e45c47014686a61554de1f26c1c1
Autor:
Andrew Arnold
Publikováno v:
Theory in Action. 15:145-151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0c9fd31ec3b70702f7d97f1d4b34b3a
https://doi.org/10.3798/tia.1937-0237.2232
https://doi.org/10.3798/tia.1937-0237.2232
Autor:
Salvatore Minisola, Andrew Arnold, Zhanna Belaya, Maria Luisa Brandi, Bart L. Clarke, Fadil M. Hannan, Lorenz C. Hofbauer, Karl L. Insogna, André Lacroix, Uri Liberman, Andrea Palermo, Jessica Pepe, René Rizzoli, Robert Wermers, Rajesh V. Thakker
Publikováno v:
Journal of Bone and Mineral Research. 37:2315-2329
In this narrative review, we present data gathered over four decades (1980-2020) on the epidemiology, pathophysiology and genetics of primary hyperparathyroidism (PHPT). PHPT is typically a disease of postmenopausal women, but its prevalence and inci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1df3542f953e9d774938a2ec80942d8
https://doi.org/10.1002/jbmr.4665
https://doi.org/10.1002/jbmr.4665
Autor:
Sarah Vincze, Nicholas V Peters, Chia-Ling Kuo, Taylor C Brown, Reju Korah, Timothy D Murtha, Justin Bellizzi, Aaliyah Riccardi, Kourosh Parham, Tobias Carling, Jessica Costa-Guda, Andrew Arnold
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:e2021-e2026
Context Multiglandular and familial parathyroid disease constitute important fractions of primary hyperparathyroidism (PHPT). Germline missense variants of GCM2, a regulator of parathyroid development, were observed in familial isolated hyperparathyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d170935820b7e40b5a84441ddc12d3
https://doi.org/10.1210/clinem/dgab929
https://doi.org/10.1210/clinem/dgab929
Autor:
null John P Bilezikian, null Aliya A Khan, null Shonni J Silverberg, null Ghada El‐Hajj Fuleihan, null Claudio Marcocci, null Salvatore Minisola, null Nancy Perrier, null Antonio Sitges‐Serra, null Rajesh V Thakker, null Gordon Guyatt, null Michael Mannstadt, null John T Potts, null Bart L Clarke, null Maria Luisa Brandi, null Andrew Arnold, null Zhanna Balaya, null Lorenz Hofbauer, null Karl Insogna, null Andre Lacroix, null Uri A. Liberman, null Andrea Palermo, null Rene Rizzoli, null Robert Wermers, null Fadil M. Hannan, null Jessica Pepe, null Cristiana Cipriani, null Richard Eastell, null Jian‐min Liu, null Ambrish Mithal, null Carolina A. Moreira, null Munro Peacock, null Barbara Silva, null Marcella Walker, null Marlene Chakhtoura, null Marian Schini, null Ola El Zein, null Martin Almquist, null Leonardo C. B. Farias, null Quan‐Yang Duh, null Brian H. Lang, null Virginia LiVolsi, null Mark Swayk, null Menno R. Vriens, null Thinh Vu, null Michael W. Yeh, null Randy Yeh, null Omar Shariq, null Leyre L. Poch, null Francisco Bandeira, null Filomena Cetani, null Manju Chandran, null Natalie E. Cusano, null Peter R. Ebeling, null Jessica Gosnell, null E. Michael Lewiecki, null Frederick R. Singer, null Morten Frost, null Anna Maria Formenti, null Tatiana Karonova, null Neil Gittoes, null Lars Rejnmark, null the International Workshop on Primary Hyperparathyroidism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565d68fd9f5143b76897681df39f1eef
https://doi.org/10.1002/jbmr.4677/v3/response1
https://doi.org/10.1002/jbmr.4677/v3/response1
Autor:
Bart L. Clarke, Rajesh V. Thakker, Christopher S. Kovacs, Michael Mannstadt, Maria-Luisa Brandi, Andrew Arnold, René Rizzoli, Elaine M. Dennison
Publikováno v:
Nature Reviews Endocrinology. 17:261-275
Biomineralization is the process by which organisms produce mineralized tissues. This crucial process makes possible the rigidity and flexibility that the skeleton needs for ambulation and protection of vital organs, and the hardness that teeth requi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fc1b02156ac9665dfba201407d9956
https://doi.org/10.1038/s41574-021-00477-2
https://doi.org/10.1038/s41574-021-00477-2
Autor:
Jessica Costa-Guda, Andrew Arnold
Publikováno v:
Journal of the Endocrine Society. 6:A885-A886
Germline, in vitro activating GCM2 variants are notably overrepresented in patients with primary hyperparathyroidism (PHPT), in both the familial and sporadic settings. While increased compared with the general population, most individuals with such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9f3531b2c82599994dcb0a48431cfeb
https://doi.org/10.1210/jendso/bvac150.1834
https://doi.org/10.1210/jendso/bvac150.1834