Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Andrew, Advani"'
Autor:
Andrew Advani, Carolyn Ziegler, Catherine H Yu, Dita Chamoun, Mathankki Ramasamy, Pauline Wijeyesekera, Cheryl Pritlove
Publikováno v:
BMJ Open, Vol 14, Iss 8 (2024)
Introduction New treatments and technologies have advanced diabetes care; however, diabetes continues to have a major impact on the daily lives of affected individuals, especially among equity-deserving groups. Evidence from patient engagement litera
Externí odkaz:
https://doaj.org/article/7c9420e9fae944b08143dca587bc6704
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Interferons (IFNs) and IFN-related pathways play key roles in the defence against microbial infection. However, these processes may also be activated during the pathogenesis of non-infectious diseases, where they may contribute to organ injury, or fu
Externí odkaz:
https://doaj.org/article/8e495ca44f914cf7a0adb6ced8192321
Autor:
Lisa Y. Q. Hong, Emily S. H. Yeung, Duc Tin Tran, Veera Ganesh Yerra, Harmandeep Kaur, M. D. Golam Kabir, Suzanne L. Advani, Youan Liu, Sri Nagarjun Batchu, Andrew Advani
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 9 (2023)
Externí odkaz:
https://doaj.org/article/9ce26968793046ee9fdc8c7f8ae9040d
Autor:
Veera Ganesh Yerra, Sri Nagarjun Batchu, Harmandeep Kaur, MD Golam Kabir, Youan Liu, Suzanne L. Advani, Duc Tin Tran, Shadi Sadeghian, Phelopater Sedrak, Filio Billia, Uros Kuzmanov, Anthony O. Gramolini, Deema O. Qasrawi, Evgeniy V. Petrotchenko, Christoph H. Borchers, Kim A. Connelly, Andrew Advani
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
Inflammation promotes adverse ventricular remodeling, a common antecedent of heart failure. Here, we set out to determine how inflammatory cells affect cardiomyocytes in the remodeling heart. Pathogenic cardiac macrophages induced an IFN response in
Externí odkaz:
https://doaj.org/article/0c5911e4a2bf433aac0c14bc3122354f
Autor:
Kim A. Connelly, Yanling Zhang, Jean-François Desjardins, Linda Nghiem, Aylin Visram, Sri N. Batchu, Verra G. Yerra, Golam Kabir, Kerri Thai, Andrew Advani, Richard E. Gilbert
Publikováno v:
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-11 (2020)
Abstract Background and aims Sodium–glucose linked cotransporter-2 (SGLT2) inhibitors reduce the likelihood of hospitalization for heart failure and cardiovascular death in both diabetic and non-diabetic individuals with reduced ejection fraction h
Externí odkaz:
https://doaj.org/article/4b4ae13147404daba5ca192e434d3681
Autor:
Kim A. Connelly, MBBS, PhD, Yanling Zhang, MD, Aylin Visram, BSc, Andrew Advani, BSc, MBChB, PhD, Sri N. Batchu, PhD, Jean-François Desjardins, MSc, Kerri Thai, BSc, Richard E. Gilbert, MBBS, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 27-37 (2019)
Summary: Recent studies send an unambiguous signal that the class of agents known as sodium-glucose–linked co-transporter-2 inhibitors (SGLT2i) prevent heart failure hospitalization in patients with type 2 diabetes. However, the mechanisms remain u
Externí odkaz:
https://doaj.org/article/47e40106a91e43e1abc3a180bfa9e722
Autor:
Patrick Meagher, Robert Civitarese, Xavier Lee, Mark Gordon, Antoinette Bugyei-Twum, Jean-Francois Desjardins, Golam Kabir, Yanling Zhang, Hari Kosanam, Aylin Visram, Howard Leong-Poi, Andrew Advani, Kim A Connelly
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252711 (2021)
BackgroundPatients with diabetes are at a high risk for developing cardiac dysfunction in the absence of coronary artery disease or hypertension, a condition known as diabetic cardiomyopathy. Contributing to heart failure is the presence of diabetic
Externí odkaz:
https://doaj.org/article/bf5e3aaf8bc74d9d816ad1580ad73504
Autor:
Veera Ganesh Yerra, Andrew Advani
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 661 (2022)
Even with recent advances in care, heart failure remains a major cause of morbidity and mortality, which urgently needs new treatments. One of the major antecedents of heart failure is pathological ventricular remodelling, the abnormal change in the
Externí odkaz:
https://doaj.org/article/f733589450fe47079343e0fd631a88d8
Publikováno v:
Expert Review of Cardiovascular Therapy. 21:15-34
Hypertension is a well-established risk factor for cardiovascular (CV) events in patients with chronic kidney disease (CKD), heart failure, obesity, and diabetes. Despite the usual prescribed antihypertensive therapies, many patients fail to achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff121b51941a9b7ccb0112f8426acef
https://doi.org/10.1080/14779072.2023.2159810
https://doi.org/10.1080/14779072.2023.2159810
Autor:
Karina Thieme, Syamantak Majumder, Angela S. Brijmohan, Sri N. Batchu, Bridgit B. Bowskill, Tamadher A. Alghamdi, Suzanne L. Advani, M. Golam Kabir, Youan Liu, Andrew Advani
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The therapeutic targeting of prostanoid subtype receptors may slow the development of chronic kidney disease (CKD) through mechanisms that are distinct from those of upstream COX inhibition. Here, employing multiple experimental models of CK
Externí odkaz:
https://doaj.org/article/3c7f7c6c5c3f478c808baefc6898c731