Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Andres V Maricq"'
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40182 (2012)
Calcium, a ubiquitous intracellular signaling molecule, controls a diverse array of cellular processes. Consequently, cells have developed strategies to modulate the shape of calcium signals in space and time. The force generating machinery in muscle
Externí odkaz:
https://doaj.org/article/4c799d6ad58a4cfea6e5903df4b0ddfc
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e6019 (2009)
BACKGROUND:Identifying the molecular mechanisms and neural circuits that control learning and memory are major challenges in neuroscience. Mammalian MAGI/S-SCAM is a multi-PDZ domain synaptic scaffolding protein that interacts with a number of postsy
Externí odkaz:
https://doaj.org/article/cf3f70c42b524aa5897bc0859b2c4f6c
Autor:
Dayton J. Goodell, Frank G. Whitby, Jerry E. Mellem, Ning Lei, Penelope J. Brockie, Aleksander J. Maricq, Debra M. Eckert, Christopher P. Hill, David M. Madsen, Andres V. Maricq
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113694- (2024)
Summary: N-methyl-D-aspartate (NMDA)-type ionotropic glutamate receptors have essential roles in neurotransmission and synaptic plasticity. Previously, we identified an evolutionarily conserved protein, NRAP-1, that is required for NMDA receptor (NMD
Externí odkaz:
https://doaj.org/article/0e71df12b48a4b31bdc42865b9f71de6
Autor:
Frédéric J. Hoerndli, Penelope J. Brockie, Rui Wang, Jerry E. Mellem, Angy Kallarackal, Rachel L. Doser, Dayton M. Pierce, David M. Madsen, Andres V. Maricq
Publikováno v:
Cell Reports. 38:110577
Synaptic plasticity depends on rapid experience-dependent changes in the number of neurotransmitter receptors. Previously, we demonstrated that motor-mediated transport of AMPA receptors (AMPARs) to and from synapses is a critical determinant of syna
Autor:
Rui Wang, Frédéric J. Hoerndli, David M. Madsen, Colin Thacker, Penelope J. Brockie, Andres V. Maricq, Jerry E. Mellem, Angy J. Kallarackal
Publikováno v:
Neuron. 86:457-474
Summary Excitatory glutamatergic synaptic transmission is critically dependent on maintaining an optimal number of postsynaptic AMPA receptors (AMPARs) at each synapse of a given neuron. Here, we show that presynaptic activity, postsynaptic potential
Autor:
Frédéric J. Hoerndli, Dane Maxfield, Andres V. Maricq, Jerry E. Mellem, David M. Madsen, Penelope J. Brockie, Rui Wang, Erica Jensen
Publikováno v:
Neuron. 80:1421-1437
Summary A primary determinant of the strength of neurotransmission is the number of AMPA-type glutamate receptors (AMPARs) at synapses. However, we still lack a mechanistic understanding of how the number of synaptic AMPARs is regulated. Here, we sho
Autor:
Frédéric J. Hoerndli, David M. Madsen, Penelope J. Brockie, Dane Maxfield, Colin Thacker, Andres V. Maricq, Tokiwa Yamasaki, Patrick Dunn, Erica Jensen, Jerry E. Mellem, Rui Wang, Michael K. Jensen, Susumu Tomita
Publikováno v:
Neuron. 80:129-142
SummaryThe strength of synaptic communication at central synapses depends on the number of ionotropic glutamate receptors, particularly the class gated by the agonist AMPA (AMPARs). Cornichon proteins, evolutionarily conserved endoplasmic reticulum c
Autor:
Linda Hauth, Craig S. Walker, Michael K. Jensen, Penelope J. Brockie, Rui Wang, Jerry E. Mellem, Frédéric J. Hoerndli, Andres V. Maricq, David M. Madsen
Publikováno v:
Neuron. 75(5):838-850
Summary The neurotransmitter glutamate mediates excitatory synaptic transmission by gating ionotropic glutamate receptors (iGluRs). AMPA receptors (AMPARs), a subtype of iGluR, are strongly implicated in synaptic plasticity, learning, and memory. We
Autor:
Julita S. Imperial, Craig S. Walker, Jose A. Matta, Stori Jensen, John T.R. Isaac, Nick Duclos, Won Yong Lee, Penelope J. Brockie, Baldomero M. Olivera, David M. Madsen, Andres V. Maricq, Michael Ellison
Publikováno v:
Current Biology. 19:900-908
Summary Background Ionotropic glutamate receptors (iGluRs) are glutamate-gated ion channels that mediate excitatory neurotransmission in the central nervous system. Based on both molecular and pharmacological criteria, iGluRs have been divided into t
Autor:
Andres V. Maricq, Penelope J. Brockie, Craig S. Walker, Rui Wang, David M. Madsen, Jerry E. Mellem, Michael M. Francis
Publikováno v:
Neuron. 59:997-1008
SummaryNeurotransmission in the brain is critically dependent on excitatory synaptic signaling mediated by AMPA-class ionotropic glutamate receptors (AMPARs). AMPARs are known to be associated with Transmembrane AMPA receptor Regulatory Proteins (TAR