Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Andres Piirsoo"'
Autor:
Krista Freimann, Piret Arukuusk, Kaido Kurrikoff, Ly Pärnaste, Raivo Raid, Andres Piirsoo, Margus Pooga, Ülo Langel
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 10, Iss , Pp 28-35 (2018)
Although advances in genomics and experimental gene therapy have opened new possibilities for treating otherwise incurable diseases, the transduction of nucleic acids into the cells and delivery in vivo remain challenging. The high molecular weight a
Externí odkaz:
https://doaj.org/article/68577712943243b5ade7880decde107e
Autor:
Kadi-Liis Veiman, Andres Piirsoo, Krista Freimann, Elin Madli Peets, Kaido Kurrikoff, Ülo Langel
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Scientific Reports
Scientific Reports
We have previously developed efficient peptide-based nucleic acid delivery vectors PF14 and NF55, where we have shown that these vectors preferentially transfect lung tissue upon systemic administration with the nucleic acid. In the current work, we
Autor:
Mario Plaas, Mait Nigul, Tuuliki Koppel, Toomas Jagomäe, Tuuli Vallisoo, Kadri Seppa, Maarja Toots, Indrek Heinla, Eero Vasar, Andres Piirsoo, Riho Meier, Miriam A Hickey, Riin Reimets, Allen Kaasik, Anton Terasmaa
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports
Scientific Reports
Wolfram syndrome (WS) is a rare autosomal-recessive disorder that is caused by mutations in the WFS1 gene and is characterized by juvenile-onset diabetes, optic atrophy, hearing loss and a number of other complications. Here, we describe the creation
Autor:
Andres Piirsoo, Margus Ennok, Ulvi Vaher, Ülle Murumets, Rita Teek, Anne Õunapuu, Eve Õiglane-Shlik, Sanna Puusepp, Tiiu Tomberg, Inga Talvik, Sander Pajusalu, Katrin Õunap, Tiia Reimand, Karit Reinson
Publikováno v:
American Journal of Medical Genetics Part A. 170:2173-2176
The CACNA1A gene encodes the transmembrane pore-forming alpha-1A subunit of the Cav 2.1 P/Q-type voltage-gated calcium channel. Several heterozygous mutations within this gene, including nonsense mutations, missense mutations, and expansion of cytosi
Autor:
Kaido Kurrikoff, Andres Piirsoo, Krista Freimann, Piret Arukuusk, Ülo Langel, Margus Pooga, Ly Pärnaste, Raivo Raid
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 10, Iss, Pp 28-35 (2018)
Molecular Therapy: Nucleic Acids, Vol 10, Iss, Pp 28-35 (2018)
Although advances in genomics and experimental gene therapy have opened new possibilities for treating otherwise incurable diseases, the transduction of nucleic acids into the cells and delivery in vivo remain challenging. The high molecular weight a
Autor:
Nadežda Peet, Frank N. Gellerich, Enn Seppet, Raivo Puhke, Lumme Kadaja, Arno Ruusalepp, Ehte Orlova, Taavi Põdramägi, Kalju Paju, Mart Roosimaa, Andres Piirsoo, Margus Eimre
Publikováno v:
Mitochondrion. 13:399-409
Cardiac energy metabolism with emphasis on mitochondria was addressed in atrial tissue from patients with overload-induced atrial dilation. Structural remodeling of dilated (D) atria manifested as intracellular accumulation of fibrillar aggregates, l
Autor:
Enn Seppet, Jaan Soplepmann, Andres Piirsoo, Margot Peetsalu, Nadežda Peet, Akseli Hemminki, Ants Peetsalu, Meeli Sirotkina, Marju Puurand
Publikováno v:
Molecular and Cellular Biochemistry. 370:69-78
The purpose of study was to comparatively characterize the oxidative phosphorylation (OXPHOS) and function of respiratory chain in mitochondria in human gastric corpus mucosa undergoing transition from normal to cancer states and in human gastric can
Publikováno v:
Ultrastructural Pathology. 41:127-128
Whipple disease (WD) is a rare disease that affects not only the small intestine in patients [1] but can also affect several other organs [2]. It is generally accepted that WD results from the bact...
Autor:
Ingrid Kalev, Erkki Juronen, Alar Sünter, Andres Piirsoo, Aavo-Valdur Mikelsaar, Peeter Toomik, Ruth Mikelsaar, Anu Kõiveer, Kalmer Karpson
Publikováno v:
Hybridoma. 29:391-401
We report the development of a new mouse anti-titin monoclonal antibody, named MAb Tit1 5H1.1, using the synthetic peptide corresponding to an amino acid sequence in the A-band of the titin molecule as immunogen. In the human skeletal muscle, MAb Tit
Autor:
Andres Piirsoo, Valdur Saks, Kersti Tepp, Lumme Kadaja, Enn SeppetE. Seppet, Nathalie Beraud, Siham ChahbounS. Chahboun, Tuuli Kaambre, Andrey V. Kuznetsov, Mart Roosimaa, Claire Monge, Sophie Pelloux, Yves Tourneur
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 87:318-326
Comparative analysis of the bioenergetic parameters of adult rat cardiomyocytes (CM) and HL-1 cells with very different structure but similar cardiac phenotype was carried out with the aim of revealing the importance of the cell structure for regulat