Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andres Obregón‐Henao"'
Autor:
Mark Schiebler, Karen Brown, Krisztina Hegyi, Sandra M Newton, Maurizio Renna, Lucy Hepburn, Catherine Klapholz, Sarah Coulter, Andres Obregón‐Henao, Marcela Henao Tamayo, Randall Basaraba, Beate Kampmann, Katherine M Henry, Joseph Burgon, Stephen A Renshaw, Angeleen Fleming, Robert R Kay, Karen E Anderson, Phillip T Hawkins, Diane J Ordway, David C Rubinsztein, Rodrigo Andres Floto
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 2, Pp 127-139 (2014)
Abstract Mycobacterium tuberculosis (MTB) remains a major challenge to global health made worse by the spread of multidrug resistance. We therefore examined whether stimulating intracellular killing of mycobacteria through pharmacological enhancement
Externí odkaz:
https://doaj.org/article/ada27d1f952241569b2948040684763a
Autor:
Taru S. Dutt, John S. Spencer, Burton R. Karger, Amy Fox, Andres Obregon-Henao, Brendan K. Podell, G. Brooke Anderson, Marcela Henao-Tamayo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Enzyme-linked immunosorbent assay (ELISA) is a technique to detect the presence of an antigen or antibody in a sample. ELISA is a simple and cost-effective method that has been used for evaluating vaccine efficacy by detecting the presence of antibod
Externí odkaz:
https://doaj.org/article/e541c6d127904cffbb00ec9adaec42d7
Autor:
Zuzana Palčeková, Andrés Obregón-Henao, Kavita De, Amanda Walz, Ha Lam, Jamie Philp, Shiva Kumar Angala, Johnathan Patterson, Camron Pearce, Sophie Zuberogoitia, Charlotte Avanzi, Jérôme Nigou, Michael McNeil, Juan F Muñoz Gutiérrez, Martine Gilleron, William H Wheat, Mercedes Gonzalez-Juarrero, Mary Jackson
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011636 (2023)
The covalent modification of bacterial (lipo)polysaccharides with discrete substituents may impact their biosynthesis, export and/or biological activity. Whether mycobacteria use a similar strategy to control the biogenesis of its cell envelope polys
Externí odkaz:
https://doaj.org/article/bb72e29f5ae744a0a16b13a47205a81c
Autor:
Ger T. Rijkers, Nynke Weterings, Andres Obregon-Henao, Michaëla Lepolder, Taru S. Dutt, Frans J. van Overveld, Marcela Henao-Tamayo
Publikováno v:
Vaccines, Vol 9, Iss 8, p 848 (2021)
Infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causes Coronavirus Disease 2019 (COVID-19), which has reached pandemic proportions. A number of effective vaccines have been produced, including mRNA vaccines and viral vecto
Externí odkaz:
https://doaj.org/article/8490baeb2a3f4388a3949c46940852a2
Autor:
Izabela K Ragan, Lindsay M Hartson, Taru S Dutt, Andres Obregon-Henao, Rachel M Maison, Paul Gordy, Amy Fox, Burton R Karger, Shaun T Cross, Marylee L Kapuscinski, Sarah K Cooper, Brendan K Podell, Mark D Stenglein, Richard A Bowen, Marcela Henao-Tamayo, Raymond P Goodrich
Publikováno v:
Vaccines, Vol 9, Iss 4, p 340 (2021)
The COVID-19 pandemic has generated intense interest in the rapid development and evaluation of vaccine candidates for this disease and other emerging diseases. Several novel methods for preparing vaccine candidates are currently undergoing clinical
Externí odkaz:
https://doaj.org/article/ae2134d385154377817932c1e948a491
Autor:
Albert B Jeon, Andrés Obregón-Henao, David F Ackart, Brendan K Podell, Juan M Belardinelli, Mary Jackson, Tuan V Nguyen, Meghan S Blackledge, Roberta J Melander, Christian Melander, Benjamin K Johnson, Robert B Abramovitch, Randall J Basaraba
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180925 (2017)
There is an urgent need to develop new drug treatment strategies to control the global spread of drug-sensitive and multidrug-resistant Mycobacterium tuberculosis (M. tuberculosis). The ß-lactam class of antibiotics is among the safest and most wide
Externí odkaz:
https://doaj.org/article/13b71f62b38642b8ae75712bb88ac78d
Autor:
Jim Sun, Vijender Singh, Alice Lau, Richard W Stokes, Andrés Obregón-Henao, Ian M Orme, Dennis Wong, Yossef Av-Gay, Zakaria Hmama
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003499 (2013)
Defining the mechanisms of Mycobacterium tuberculosis (Mtb) persistence in the host macrophage and identifying mycobacterial factors responsible for it are keys to better understand tuberculosis pathogenesis. The emerging picture from ongoing studies
Externí odkaz:
https://doaj.org/article/7337e941e463468787ed22380ba6d8b9
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80669 (2013)
Tuberculosis is one of the world's leading killers, stealing 1.4 million lives and causing 8.7 million new and relapsed infections in 2011. The only vaccine against tuberculosis is BCG which demonstrates variable efficacy in adults worldwide. Human i
Externí odkaz:
https://doaj.org/article/f0082fa4173a45f5939507a6c84e36ce
Autor:
Gopinath S Palanisamy, Natalie M Kirk, David F Ackart, Andrés Obregón-Henao, Crystal A Shanley, Ian M Orme, Randall J Basaraba
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34148 (2012)
The typical host response to infection of humans and some animals by M. tuberculosis is the accumulation of reactive oxygen species generating inflammatory cells into discrete granulomas, which frequently develop central caseous necrosis. In previous
Externí odkaz:
https://doaj.org/article/70494065d5ad4bb6ad2dd0a766bce4e3
Autor:
Andrés Obregón-Henao, María A Duque-Correa, Mauricio Rojas, Luis F García, Patrick J Brennan, Blanca L Ortiz, John T Belisle
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29970 (2012)
The molecular basis of pathogen-induced host cell apoptosis is well characterized for a number of microorganisms. Mycobacterium tuberculosis is known to induce apoptosis and it was shown that live but not heat killed M. tuberculosis stimulates this b
Externí odkaz:
https://doaj.org/article/e1cca81569d44803969638df4e51c9e5