Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Andres F Vallejo"'
Autor:
Aymen Al-Shamkhani, Marta E Polak, Pauline Rettman, Matthew D Blunt, Rebecca J Fulton, Andres F Vallejo, Leidy Y Bastidas-Legarda, Laura España-Serrano, Christelle Retiere, Salim I Khakoo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Natural killer (NK) cells are increasingly being recognized as agents for cancer immunotherapy. The killer cell immunoglobulin-like receptors (KIRs) are expressed by NK cells and are immunogenetic determinants of the outcome of cancer. In
Externí odkaz:
https://doaj.org/article/ace849bd921c4f8a8075efbe163b9ccb
Autor:
Taopeng Wang, Michael J. Roach, Kate Harvey, Javier Escudero Morlanes, Beata Kiedik, Ghamdan Al-Eryani, Alissa Greenwald, Nikolaos Kalavros, Felipe Segato Dezem, Yuling Ma, Yered H. Pita-Juarez, Kellie Wise, Cyril Degletagne, Anna Elz, Azi Hadadianpour, Jack Johanneson, Fiona Pakiam, Heeju Ryu, Evan W. Newell, Laurie Tonon, Andrew Kohlway, Tingsheng Drennon, Jawad Abousoud, Ryan Stott, Paul Lund, Jens Durruthy, Andres F. Vallejo, Wenyan Li, Robert Salomon, Dominik Kaczorowski, Joanna Warren, Lisa M. Butler, Sandra O’Toole, Jasmine Plummer, Ioannis S. Vlachos, Joakim Lundeberg, Alexander Swarbrick, Luciano G. Martelotto
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Formalin-fixed paraffin-embedded (FFPE) samples are valuable but underutilized in single-cell omics research due to their low RNA quality. In this study, leveraging a recent advance in single-cell genomic technology, we introduce snPATHO-seq
Externí odkaz:
https://doaj.org/article/e72696809e1b4d6fbd26435761d09282
Autor:
David J Winter, M Andreína Pacheco, Andres F Vallejo, Rachel S Schwartz, Myriam Arevalo-Herrera, Socrates Herrera, Reed A Cartwright, Ananias A Escalante
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 12, p e0004252 (2015)
Plasmodium vivax is the most prevalent malarial species in South America and exerts a substantial burden on the populations it affects. The control and eventual elimination of P. vivax are global health priorities. Genomic research contributes to thi
Externí odkaz:
https://doaj.org/article/ceeb209d07bd43f39610111209a198fe
Autor:
Joseph A. Bell, Elizabeth R. Davies, Christopher J. Brereton, Milica Vukmirovic, James J.W. Roberts, Kerry Lunn, Leanne Wickens, Franco Conforti, Robert A. Ridley, Jessica Ceccato, Lucy N. Sayer, David A. Johnston, Andres F. Vallejo, Aiman Alzetani, Sanjay Jogai, Ben G. Marshall, Aurelie Fabre, Luca Richeldi, Phillip D. Monk, Paul Skipp, Naftali Kaminski, Emily Offer, Yihua Wang, Donna E. Davies, Mark G. Jones
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101695- (2024)
Summary: Matrix stiffening by lysyl oxidase-like 2 (LOXL2)-mediated collagen cross-linking is proposed as a core feedforward mechanism that promotes fibrogenesis. Failure in clinical trials of simtuzumab (the humanized version of AB0023, a monoclonal
Externí odkaz:
https://doaj.org/article/28bf070de21f4af1b6319da757012509
Autor:
Sofia Sirvent, Andres F. Vallejo, Emma Corden, Ying Teo, James Davies, Kalum Clayton, Eleanor G. Seaby, Chester Lai, Sarah Ennis, Rfeef Alyami, Gemma Douilhet, Lareb S. N. Dean, Matthew Loxham, Sarah Horswill, Eugene Healy, Graham Roberts, Nigel J. Hall, Peter S. Friedmann, Harinder Singh, Clare L. Bennett, Michael R Ardern-Jones, Marta E. Polak
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Regulation of cutaneous immunity is severely compromised in inflammatory skin disease. To investigate the molecular crosstalk underpinning tolerance versus inflammation in atopic dermatitis, we utilise a human in vivo allergen challenge stud
Externí odkaz:
https://doaj.org/article/8a9e3b6f395949309fb497cf8ddaabc0
Autor:
Rebekah Penrice-Randal, Xiaofeng Dong, Andrew George Shapanis, Aaron Gardner, Nicholas Harding, Jelmer Legebeke, Jenny Lord, Andres F. Vallejo, Stephen Poole, Nathan J. Brendish, Catherine Hartley, Anthony P. Williams, Gabrielle Wheway, Marta E. Polak, Fabio Strazzeri, James P. R. Schofield, Paul J. Skipp, Julian A. Hiscox, Tristan W. Clark, Diana Baralle
Publikováno v:
Frontiers in Immunology. 13
BackgroundThe COVID-19 pandemic has created pressure on healthcare systems worldwide. Tools that can stratify individuals according to prognosis could allow for more efficient allocation of healthcare resources and thus improved patient outcomes. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b758c555db7f83ac58596a2318388636
https://doi.org/10.3389/fimmu.2022.988685
https://doi.org/10.3389/fimmu.2022.988685
Autor:
James Davies, Sofia Sirvent, Andres F. Vallejo, Kalum Clayton, Gemma Douilhet, Patrick S. Keeler, Jonathan West, Michael Ardern-Jones, Ben D. MacArthur, Harinder Singh, Marta E. Polak
Publikováno v:
Frontiers in Immunology. 13
Human epidermal Langerhans cells (LCs) maintain immune homeostasis in the skin. To examine transcriptional programming of human primary LCs during homeostasis, we performed scRNA-seq analysis of LCs before and after migration from the epidermis, coup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23aa88c996970cf2074b8ff4a741e1a7
https://doi.org/10.3389/fimmu.2022.892254
https://doi.org/10.3389/fimmu.2022.892254
Autor:
Andres F Vallejo, Kate Harvey, Taopeng Wang, Kellie Wise, Lisa M. Butler, Jose Polo, Jasmine Plummer, Alex Swarbrick, Luciano G Martelotto
FFPE (formalin-fixed, paraffin-embedded) tissue archives are the largest repository of clinically annotated human specimens. Despite numerous advances in technology, current methods for sequencing of FFPE-fixed single-cells are slow, labour intensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f18c046ec347a6ffd71d37d3a2d5db6f
https://doi.org/10.1101/2022.08.23.505054
https://doi.org/10.1101/2022.08.23.505054
Autor:
Jelmer Legebeke, Jenny Lord, Rebekah Penrice-Randal, Andres F. Vallejo, Stephen Poole, Nathan J. Brendish, Xiaofeng Dong, Catherine Hartley, John W. Holloway, Jane S. Lucas, Anthony P. Williams, Gabrielle Wheway, Fabio Strazzeri, Aaron Gardner, James P. R. Schofield, Paul J. Skipp, Julian A. Hiscox, Marta E. Polak, Tristan W. Clark, Diana Baralle
Publikováno v:
FRONTIERS IN IMMUNOLOGY
The worldwide COVID-19 pandemic has claimed millions of lives and has had a profound effect on global life. Understanding the body’s immune response to SARS-CoV-2 infection is crucial in improving patient management and prognosis. In this study we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab3ba81c9eeb982604f1698e2d8853a
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