Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Andres F Oberhauser"'
Autor:
Hiroshi Qadota, Annie McPherson, Rachel Corbitt, Evan Kelton Dackowski, Yohei Matsunaga, Andres F Oberhauser, Guy M Benian
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 12, Iss 7 (2022)
AbstractIntegrin plays a crucial role in the attachment of cells to the extracellular matrix. Integrin recruits many proteins intracellularly, including a 4-protein complex (kindlin, ILK, PINCH, and parvin). Caenorhabditis elegansCaenorhabditis elega
Externí odkaz:
https://doaj.org/article/eea7a71f2491439e8ffcd613729671da
Publikováno v:
bioRxiv
Protein phosphatase 2A (PP2A) functions in a variety of cellular contexts. PP2A can assemble into four different complexes based on the inclusion of different regulatory or targeting subunits. The B’’’ regulatory subunit “striatin” forms th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec96d18641233667446a95575d45a85
https://europepmc.org/articles/PMC10028798/
https://europepmc.org/articles/PMC10028798/
Publikováno v:
Subcellular Biochemistry ISBN: 9783031147395
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbe941e45b489be35a418984e0bdf225
https://doi.org/10.1007/978-3-031-14740-1_7
https://doi.org/10.1007/978-3-031-14740-1_7
Publikováno v:
Sub-cellular biochemistry. 101
The UCS (UNC-45/CRO1/She4p) family of proteins has emerged as chaperones specific for the folding, assembly, and function of myosin. UCS proteins participate in various myosin-dependent cellular processes including myofibril organization and muscle f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5cc175cc6eed4004e46cb1804fc0433d
https://pubmed.ncbi.nlm.nih.gov/36520308
https://pubmed.ncbi.nlm.nih.gov/36520308
Autor:
John Miller, Taylor Moncrief, Guy M. Benian, Ivana Gaziova, Courtney J. Matheny, Hiroshi Qadota, Andres F. Oberhauser
Publikováno v:
Protein Sci
Proper muscle development and function depend on myosin being properly folded and integrated into the thick filament structure. For this to occur the myosin chaperone UNC-45, or UNC-45B, must be present and able to chaperone myosin. Here we use a com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3eb522ca3933bdb14d2ca583defd991
https://doi.org/10.1002/pro.4180
https://doi.org/10.1002/pro.4180
Autor:
Courtney J. Matheny, Hiroshi Qadota, Marion Kimelman, Aaron O. Bailey, Andres F. Oberhauser, Guy M. Benian
Summary/AbstractAs people live longer, age-related diseases, like sarcopenia, will become a greater public health concern. We use the model organism C. elegans to better understand the molecular mechanisms behind muscle maintenance. Muscle function i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::456a23962dbeb69cab8aa8d9bb7a7490
https://doi.org/10.1101/2022.06.04.494828
https://doi.org/10.1101/2022.06.04.494828
Autor:
Guy M. Benian, Courtney J. Christian, Simon Powell, Taylor Moncrief, Hubert Lee, Michael Villarreal, Hiroshi Qadota, Andres F. Oberhauser, Ivana Gaziova, Mark A. White
Publikováno v:
Biophys J
UNC-45B is a multidomain molecular chaperone that is essential for the proper folding and assembly of myosin into muscle thick filaments in vivo. It has previously been demonstrated that the UCS domain is responsible for the chaperone-like properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68371da99cb44f6095d2bd3e534cb601
https://doi.org/10.1016/j.bpj.2020.07.012
https://doi.org/10.1016/j.bpj.2020.07.012
Autor:
J. P. Renn, Andres F. Oberhauser, John F. Marko, H. Bai, Sucharita Bhattacharyya, Dmitrii E. Makarov, Chengzhi He, Hongbin Li, Andreas T Matouschek
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
We investigated the mechanical unfolding of single spectrin molecules over a broad range of loading rates and thus unfolding forces by combining magnetic tweezers with atomic force microscopy. We find that the mean unfolding force increases logarithm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4525504c6b7a2a000a14756e1ea8f04f
http://link.springer.com/article/10.1038/s41598-019-46525-w
http://link.springer.com/article/10.1038/s41598-019-46525-w
Autor:
Celeste C. Finnerty, Jianhua Gu, Amina El Ayadi, Paul J. Boor, Linda E. Sousse, Zhenping Chen, David N. Herndon, Jia Zhou, Andres F. Oberhauser
Publikováno v:
Toxicology and Applied Pharmacology. 362:9-19
Hypertrophic scars (HS) limit movement, decrease quality of life, and remain a major impediment to rehabilitation from burns. However, no effective pharmacologic therapies for HS exist. Here we tested the in vitro anti-fibrotic effects of the novel c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f80d0b870c2ce11c739e99aca572c2
https://doi.org/10.1016/j.taap.2018.09.026
https://doi.org/10.1016/j.taap.2018.09.026
Autor:
Guy M. Benian, Courtney J. Matheny, Ivana Gaziova, Hiroshi Qadota, Andres F. Oberhauser, Taylor Moncrief, John Miller
Proper muscle development and function depends on myosin being properly folded and integrated into the thick filament structure. For this to occur the myosin chaperone UNC-45, or UNC-45B, must be present and able to chaperone myosin. Here we use a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38e8644431c0d801ab36aa54fc884d34
https://doi.org/10.1101/2021.05.07.443121
https://doi.org/10.1101/2021.05.07.443121