Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Andres E. Lukach"'
Publikováno v:
Molecules, Vol 29, Iss 13, p 3011 (2024)
Solifenacin (SFC) is a potent muscarinic antagonist that effectively reduces bladder muscle contraction, thereby alleviating symptoms such as frequency of micturition and urgency. Oxidation of SFC leads to the formation of impurities like Impurity K.
Externí odkaz:
https://doaj.org/article/42af68b57e0443c49359fdeb4f812e1d
Publikováno v:
Tetrahedron. 57:2419-2425
The strain of the bisnoradamantane skeleton is shown by: (i) the easy homoketonization of tricyclo[3.3.0.0 3,7 ]octane-1,5-diol, 2a , to exo -7-hydroxy- cis -bicyclo[3.3.0]octan-3-one, 3a , under silica gel column chromatography, and (ii) the cleavag
Publikováno v:
Tetrahedron. 56:2703-2707
Carboxylic acids are bromodecarboxylated in moderate to good yields on reaction with iodosobenzene diacetate and bromine under irradiation with a tungsten lamp. The reaction works very well with carboxylic acids having a primary, secondary or tertiar
Autor:
Roberto A. Rossi, Andres E. Lukach
Publikováno v:
The Journal of Organic Chemistry. 64:5826-5831
The reaction of 2-iodoadamantane (1) with the potassium enolate of acetophenone (2) did not occur in the dark but succeeded under irradiation or in the presence of FeBr2 to give the substitution product 3 in 62% and 88% yields, respectively. The phot
Publikováno v:
The Journal of Organic Chemistry. 62:4260-4265
The reactions of 1,3-dihaloadamantanes with various carbanionic nucleophiles were studied. Potassium enolates of acetophenone (2) and pinacolone (10b) and the anion of nitromethane (10a) reacted with 1,3-diiodoadamantane (1a) in DMSO under photostimu
Publikováno v:
The Journal of Organic Chemistry. 60:1000-1004
Publikováno v:
Journal of Physical Organic Chemistry. 7:610-614
The reactivity of 1,3-dihaloadamantanes with diphenylphosphide ions (Ph2P−) in liquid ammonia was studied. 1,3-Dichloroadamantane (1a), 1-bromo-3-chloroadamantane (1b) and 1,3-dibromoadamantane (1c) reacted with Ph2P− ions under photostimulation
Autor:
Roberto A. Rossi, Andres E. Lukach
Publikováno v:
ChemInform. 30
The reaction of 2-iodoadamantane (1) with the potassium enolate of acetophenone (2) did not occur in the dark but succeeded under irradiation or in the presence of FeBr2 to give the substitution product 3 in 62% and 88% yields, respectively. The phot
Publikováno v:
ChemInform. 31
Carboxylic acids are bromodecarboxylated in moderate to good yields on reaction with iodosobenzene diacetate and bromine under irradiation with a tungsten lamp. The reaction works very well with carboxylic acids having a primary, secondary or tertiar
Publikováno v:
ChemInform. 32
The strain of the bisnoradamantane skeleton is shown by: (i) the easy homoketonization of tricyclo[3.3.0.0 3,7 ]octane-1,5-diol, 2a , to exo -7-hydroxy- cis -bicyclo[3.3.0]octan-3-one, 3a , under silica gel column chromatography, and (ii) the cleavag