Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andres Cruz-Herranz"'
Autor:
Borje Darpo, Michal Geva, Georg Ferber, Yigal Paul Goldberg, Andres Cruz-Herranz, Munish Mehra, Richard Kovacs, Michael R. Hayden
Publikováno v:
Neurology and Therapy, Vol 12, Iss 2, Pp 597-617 (2023)
Abstract Introduction Pridopidine is a highly selective sigma-1 receptor (S1R) agonist in development for the treatment of Huntington’s disease (HD) and amyotrophic lateral sclerosis (ALS). Pridopidine’s activation of S1R enhances cellular proces
Externí odkaz:
https://doaj.org/article/8aac3a828618475eb11cb8502f0f5d75
Autor:
Maurits F. J. M. Vissers, Jules A. A. C. Heuberger, Geert Jan Groeneveld, Jerome Oude Nijhuis, Peter Paul De Deyn, Salah Hadi, Jeffrey Harris, Richard M. Tsai, Andres Cruz‐Herranz, Fen Huang, Vincent Tong, Rebecca Erickson, Yuda Zhu, Kimberly Scearce‐Levie, Jennifer Hsiao‐Nakamoto, Xinyan Tang, Megan Chang, Brian M. Fox, Anthony A. Estrada, Robert J. Pomponio, Miguel Alonso‐Alonso, Moshe Zilberstein, Nazem Atassi, Matthew D. Troyer, Carole Ho
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 8, Pp 2010-2023 (2022)
Abstract RIPK1 is a master regulator of inflammatory signaling and cell death and increased RIPK1 activity is observed in human diseases, including Alzheimer’s disease (AD) and amyotrophic lateral sclerosis (ALS). RIPK1 inhibition has been shown to
Externí odkaz:
https://doaj.org/article/b9ff23b0f0ad4f13a0f534eb7f32e626
Autor:
Christian Cordano, Jung H Sin, Garrett Timmons, Hao H Yiu, Karin Stebbins, Caroline Guglielmetti, Andres Cruz-Herranz, Wendy Xin, Daniel Lorrain, Jonah R Chan, Ari J Green
Publikováno v:
Brain : a journal of neurology, vol 145, iss 11
Brain
Brain
Many biomarkers in clinical neuroscience lack pathological certification. This issue is potentially a significant contributor to the limited success of neuroprotective and neurorestorative therapies for human neurological disease—and is evident eve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa0e05b23a5232cdf413a12f9f96b8f
https://doi.org/10.1093/brain/awac207
https://doi.org/10.1093/brain/awac207
Autor:
Maurits F. J. M. Vissers, Jules A. A. C. Heuberger, Geert Jan Groeneveld, Jerome Oude Nijhuis, Peter Paul De Deyn, Salah Hadi, Jeffrey Harris, Richard M. Tsai, Andres Cruz‐Herranz, Fen Huang, Vincent Tong, Rebecca Erickson, Yuda Zhu, Kimberly Scearce‐Levie, Jennifer Hsiao‐Nakamoto, Xinyan Tang, Megan Chang, Brian M. Fox, Anthony A. Estrada, Robert J. Pomponio, Miguel Alonso‐Alonso, Moshe Zilberstein, Nazem Atassi, Matthew D. Troyer, Carole Ho
Publikováno v:
Clinical and Translational Science. 15:2010-2023
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95cdda02d84a3c460709facb87673a93
https://doi.org/10.1111/cts.13317
https://doi.org/10.1111/cts.13317
Autor:
Hannah Kapell, Luca Fazio, Julia Dyckow, Sophia Schwarz, Andrés Cruz-Herranz, Christina Mayer, Joaquin Campos, Elisa D’Este, Wiebke Möbius, Christian Cordano, Anne-Katrin Pröbstel, Marjan Gharagozloo, Amel Zulji, Venu Narayanan Naik, Anna Delank, Manuela Cerina, Thomas Müntefering, Celia Lerma-Martin, Jana K. Sonner, Jung Hyung Sin, Paul Disse, Nicole Rychlik, Khalida Sabeur, Manideep Chavali, Rajneesh Srivastava, Matthias Heidenreich, Kathryn C. Fitzgerald, Guiscard Seebohm, Christine Stadelmann, Bernhard Hemmer, Michael Platten, Thomas J. Jentsch, Maren Engelhardt, Thomas Budde, Klaus-Armin Nave, Peter A. Calabresi, Manuel A. Friese, Ari J. Green, Claudio Acuna, David H. Rowitch, Sven G. Meuth, Lucas Schirmer
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 7 (2023)
Multiple sclerosis (MS) is a progressive inflammatory demyelinating disease of the CNS. Increasing evidence suggests that vulnerable neurons in MS exhibit fatal metabolic exhaustion over time, a phenomenon hypothesized to be caused by chronic hyperex
Externí odkaz:
https://doaj.org/article/3d8107c041ee41648aa17c5d82d19237
Autor:
Angel Martin Montes, Andres Cruz Herranz, Patricia Martínez-Sánchez, Elisa Correas Callero, Gerardo Ruiz Ares, Exuperio Díez-Tejedor, Maria de los Angeles Mangas Guijarro, Marta Martínez, Blanca Fuentes Gimeno
Publikováno v:
Stroke. 43
INTRODUCTION: The yield of serial electrocardiograms (ECG) plus 72-hour cardiac monitoring and Holter monitoring in detection of paroxysmal atrial fibrillation (PAF) is not well known. METHODS: consecutive patients with stroke or transient ischemic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90da7fef34717d52fc32ae0b1102a6ba
https://doi.org/10.1161/str.43.suppl_1.a3648
https://doi.org/10.1161/str.43.suppl_1.a3648
Autor:
Andrés Cruz-Herranz, Frederike C. Oertel, Kicheol Kim, Ester Cantó, Garrett Timmons, Jung H. Sin, Michael Devereux, Nicholas Baker, Brady Michel, Ryan D. Schubert, Lakshmisahithi Rani, Christian Cordano, Sergio E. Baranzini, Ari J. Green
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
Neurodegeneration mediates neurological disability in inflammatory demyelinating diseases of the CNS. The role of innate immune cells in mediating this damage has remained controversial with evidence for destructive and protective effects. This has c
Externí odkaz:
https://doaj.org/article/01c7e3c7a8404c0582e553222861c0db
Autor:
Andrés Cruz-Herranz, Michael Dietrich, Alexander M. Hilla, Hao H. Yiu, Marc H. Levin, Christina Hecker, Andrea Issberner, Angelika Hallenberger, Christian Cordano, Klaus Lehmann-Horn, Lisanne J. Balk, Orhan Aktas, Jens Ingwersen, Charlotte von Gall, Hans-Peter Hartung, Scott S. Zamvil, Dietmar Fischer, Philipp Albrecht, Ari J. Green
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-17 (2019)
Abstract Background Retinal optical coherence tomography (OCT) is a clinical and research tool in multiple sclerosis, where it has shown significant retinal nerve fiber (RNFL) and ganglion cell (RGC) layer thinning, while postmortem studies have repo
Externí odkaz:
https://doaj.org/article/6292cc19ece1420483d1add71284f30e
Autor:
Lucas Schirmer, Wiebke Möbius, Chao Zhao, Andrés Cruz-Herranz, Lucile Ben Haim, Christian Cordano, Lawrence R Shiow, Kevin W Kelley, Boguslawa Sadowski, Garrett Timmons, Anne-Katrin Pröbstel, Jackie N Wright, Jung Hyung Sin, Michael Devereux, Daniel E Morrison, Sandra M Chang, Khalida Sabeur, Ari J Green, Klaus-Armin Nave, Robin JM Franklin, David H Rowitch
Publikováno v:
eLife, Vol 7 (2018)
Glial support is critical for normal axon function and can become dysregulated in white matter (WM) disease. In humans, loss-of-function mutations of KCNJ10, which encodes the inward-rectifying potassium channel KIR4.1, causes seizures and progressiv
Externí odkaz:
https://doaj.org/article/08a072ddc3c447a1bdecec41fc96cfc9