Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Andres, Männik"'
Autor:
Kiira Gildemann, Mari-Liis Tsernant, Laura Liivand, Retti Ennomäe, Väino Poikalainen, Lembit Lepasalu, Siimu Rom, Ants Kavak, Robert Marsden Cox, Josef Dieter Wolf, Carolin Maria Lieber, Richard Karl Plemper, Andres Männik, Mart Ustav, Jr., Mart Ustav, Joachim Matthias Gerhold
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110326- (2024)
Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread in the population. We recently reported the production of bovine colostrum-derived antibodies that can neutralize the virus. These have been formulated into a n
Externí odkaz:
https://doaj.org/article/4a26311eb5124ea19ecbfdef3d1c104d
Autor:
Kadri Kangro, Elien Roose, An‐Sofie Schelpe, Edwige Tellier, Gilles Kaplanski, Jan Voorberg, Simon F. De Meyer, Andres Männik, Karen Vanhoorelbeke
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 5, Pp 918-930 (2020)
Abstract Background In immune‐mediated thrombotic thrombocytopenic purpura (iTTP), patients develop an immune response against the multidomain enzyme ADAMTS13. ADAMTS13 consists of a metalloprotease (M) and disintegrin‐like (D) domain, 8 thrombos
Externí odkaz:
https://doaj.org/article/1b08d655e5664beab1e9d966ee70984e
Autor:
Kadri Kangro, Mihhail Kurašin, Kiira Gildemann, Eve Sankovski, Eva Žusinaite, Laura Sandra Lello, Raini Pert, Ants Kavak, Väino Poikalainen, Lembit Lepasalu, Marilin Kuusk, Robin Pau, Sander Piiskop, Siimu Rom, Ruth Oltjer, Kairi Tiirik, Karin Kogermann, Mario Plaas, Toomas Tiirats, Birgit Aasmäe, Mihkel Plaas, Karl Mumm, Dagni Krinka, Ene Talpsep, Meelis Kadaja, Joachim M. Gerhold, Anu Planken, Andres Tover, Andres Merits, Andres Männik, Mart Ustav
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to impose a serious burden on health systems globally. Despite worldwide vaccination, social distancing and wearing masks, the spread of the virus is ongoing. One of the mechanism
Externí odkaz:
https://doaj.org/article/ded5bb1380934dd8b51d32fab3b9098b
Autor:
Kadri Kangro, Elien Roose, Charlotte Dekimpe, Aline Vandenbulcke, Nuno A.G. Graça, Jan Voorberg, Mart Ustav, Andres Männik, Karen Vanhoorelbeke
Publikováno v:
Journal of thrombosis and haemostasis, 20(10), 2379-2385. Wiley-Blackwell
BACKGROUND: Recombinant human ADAMTS13 (rADAMTS13) is a key protein in fundamental research for investigating its mode of action and the pathophysiology of thrombotic thrombocytopenic purpura (TTP). However, the expression of rADAMTS13 is quite low i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a268001a99c840323f48316298fa549
http://www.scopus.com/inward/record.url?scp=85135112940&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85135112940&partnerID=8YFLogxK
Autor:
Nuno A.G. Graça, Bogac Ercig, Leydi Carolina Velásquez Pereira, Kadri Kangro, Paul Kaijen, Gerry A.F. Nicolaes, Agnès Veyradier, Paul Coppo, Karen Vanhoorelbeke, Andres Männik, Jan Voorberg
Publikováno v:
Haematologica, Vol 105, Iss 11 (2019)
Antibodies that develop in patients with immune thrombotic thrombocytopenic purpura (iTTP) commonly target the spacer epitope R568/F592/R660/Y661/Y665 (RFRYY). In this study we present a detailed contribution of each residue in this epitope for autoa
Externí odkaz:
https://doaj.org/article/7743c3d8b3554d9fa6ce5c0e5f4fd05c
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211235 (2019)
Due to the extreme tissue and species restriction of the papillomaviruses (PVs), there is a great need for animal models that accurately mimic PV infection in humans for testing therapeutic strategies against human papillomaviruses (HPVs). In this st
Externí odkaz:
https://doaj.org/article/4f2eacc2717e492099d6f745459f51a0
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006168 (2017)
Human papillomaviruses (HPVs) are oncogenic viruses that cause numerous different cancers as well as benign lesions in the epithelia. To date, there is no effective cure for an ongoing HPV infection. Here, we describe the generation process of a plat
Externí odkaz:
https://doaj.org/article/26a81ea166554808a3fb7710450b6b5d
Autor:
Chris P. M. Reutelingsperger, Andres Männik, Karen Vanhoorelbeke, Johana Hrdinova, Jan Voorberg, Paul Coppo, Agnès Veyradier, Kadri Kangro, Bogac Ercig, Kanin Wichapong, Gerry A. F. Nicolaes, Tom Arfman, Nuno A. G. Graça, Floris P. J. van Alphen, Paul H. P. Kaijen, Maartje van den Biggelaar
Publikováno v:
Blood, 137(19), 2694-2698. American Society of Hematology
Blood, 137(19), 2694-2698. The American Society of Hematology
Blood, 137(19), 2694-2698. The American Society of Hematology
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is an autoimmune disorder caused by the development of autoantibodies targeting different domains of ADAMTS13. Profiling studies have shown that residues R568, F592, R660, Y661, and Y665 with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db71bd1c8dbb5a502eb30028fd181eb5
https://cris.maastrichtuniversity.nl/en/publications/0f08a6a9-a6aa-4ae3-85ca-bbb4177342b6
https://cris.maastrichtuniversity.nl/en/publications/0f08a6a9-a6aa-4ae3-85ca-bbb4177342b6
Autor:
Siret Tahk, Kai Virumäe, Paule Hermet, Korneelia Anton, Maiken Abel, Denis Belitškin, Luciano Galdieri, Steven Garner, Jillian Krings, Kaleb Collver, Emily Hoehn, Brendan Lahm, Kaitlyne Powers, Tuuli Käämbre, Alastair J. King, Francisca Neethling, Anu Planken, Mart Ustav, Andres Männik
Publikováno v:
Cancer Research. 83:6036-6036
Background: Alterations in tumor cell metabolism are one of the central processes guiding cancer progression. The increased glucose dependence of cancer cells, also known as the Warburg effect, opens the possibility to therapeutically target the glyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ea78edd99121f74d00419f9e725c673
https://doi.org/10.1158/1538-7445.am2023-6036
https://doi.org/10.1158/1538-7445.am2023-6036
Autor:
Jan Voorberg, Andres Männik, Paul H. P. Kaijen, Gerry A. F. Nicolaes, Karen Vanhoorelbeke, Paul Coppo, Nuno A. G. Graça, Agnès Veyradier, Bogac Ercig, Kadri Kangro, Leydi Carolina Velásquez Pereira
Publikováno v:
Haematologica, 105(11), 2619-2630. Ferrata Storti Foundation
Haematologica
Haematologica-the Hematology Journal, 105(11), 2619-2630. Ferrata Storti Foundation
Haematologica
Haematologica-the Hematology Journal, 105(11), 2619-2630. Ferrata Storti Foundation
Antibodies that develop in patients with immune thrombotic thrombocytopenic purpura commonly target the spacer epitope R568/F592/R660/Y661/Y665 (RFRYY) of ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13). I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c363e8c8e9886a3df09d6d2728f935e4
https://cris.maastrichtuniversity.nl/en/publications/2b99e246-61bc-49b3-804d-c85d36f6bcb1
https://cris.maastrichtuniversity.nl/en/publications/2b99e246-61bc-49b3-804d-c85d36f6bcb1