Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Andreja Ambriović-Ristov"'
The extracellular matrix component perlecan/HSPG2 regulates radioresistance in prostate cancer cells
Autor:
Ivana Samaržija, Vasyl Lukiyanchuk, Marija Lončarić, Anja Rac-Justament, Nikolina Stojanović, Ielizaveta Gorodetska, Uğur Kahya, Jonathan D. Humphries, Mahak Fatima, Martin J. Humphries, Ana Fröbe, Anna Dubrovska, Andreja Ambriović-Ristov
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Radiotherapy of prostate cancer (PC) can lead to the acquisition of radioresistance through molecular mechanisms that involve, in part, cell adhesion-mediated signaling. To define these mechanisms, we employed a DU145 PC model to conduct a comparativ
Externí odkaz:
https://doaj.org/article/1313c7d198bb45ab93487b56f75e5c06
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-25 (2024)
Abstract Background The R-RAS2 is a small GTPase highly similar to classical RAS proteins at the regulatory and signaling levels. The high evolutionary conservation of R-RAS2, its links to basic cellular processes and its role in cancer, make R-RAS2
Externí odkaz:
https://doaj.org/article/eb610082c1004645855ce823dc4e737c
Autor:
Marija Lončarić, Nikolina Stojanović, Anja Rac-Justament, Kaatje Coopmans, Dragomira Majhen, Jonathan D. Humphries, Martin J. Humphries, Andreja Ambriović-Ristov
Publikováno v:
Cellular & Molecular Biology Letters, Vol 28, Iss 1, Pp 1-23 (2023)
Abstract Background Focal adhesions (FAs) are integrin-containing, multi-protein structures that link intracellular actin to the extracellular matrix and trigger multiple signaling pathways that control cell proliferation, differentiation, survival a
Externí odkaz:
https://doaj.org/article/66941f83217e498daba36fd9986d82f0
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/c89494250b4d46058ded1a04ef405265
Autor:
Ana Tadijan, Jonathan D. Humphries, Ivana Samaržija, Nikolina Stojanović, Junzhe Zha, Kristina Čuljak, Marija Tomić, Mladen Paradžik, Davor Nestić, Heemin Kang, Martin J. Humphries, Andreja Ambriović-Ristov
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Integrins are heterodimeric cell surface glycoproteins used by cells to bind to the extracellular matrix (ECM) and regulate tumor cell proliferation, migration and survival. A causative relationship between integrin expression and resistance to antic
Externí odkaz:
https://doaj.org/article/e8c471c862da466bbeca602d980d2c4d
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Nascent adhesions are submicron transient structures promoting the early adhesion of cells to the extracellular matrix. Nascent adhesions typically consist of several tens of integrins, and serve as platforms for the recruitment and activation of pro
Externí odkaz:
https://doaj.org/article/c3965e6b74b84cd78517aed45c287364
Autor:
Davor Nestić, Ksenija Božinović, Isabela Drašković, Alen Kovačević, Jolien van den Bosch, Jelena Knežević, Jerome Custers, Andreja Ambriović-Ristov, Dragomira Majhen
Publikováno v:
Viruses, Vol 14, Iss 4, p 672 (2022)
The low seroprevalent human adenovirus type 26 (HAdV26)-based vaccine vector was the first adenovirus-based vector to receive marketing authorization from European Commission. HAdV26-based vaccine vectors induce durable humoral and cellular immune re
Externí odkaz:
https://doaj.org/article/610452466beb4576bcd63abc165c9902
Autor:
Mladen Paradžik, Jonathan D. Humphries, Nikolina Stojanović, Davor Nestić, Dragomira Majhen, Ana Dekanić, Ivana Samaržija, Delphine Sedda, Igor Weber, Martin J. Humphries, Andreja Ambriović-Ristov
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Integrins are heterodimeric glycoproteins that bind cells to extracellular matrix. Upon integrin clustering, multimolecular integrin adhesion complexes (IACs) are formed, creating links to the cell cytoskeleton. We have previously observed decreased
Externí odkaz:
https://doaj.org/article/46803868741245578b75ccb653bc8f3e
Autor:
Ivana Strazic Geljic, Paola Kucan Brlic, Lucija Musak, Dubravka Karner, Andreja Ambriović-Ristov, Stipan Jonjic, Peter Schu, Tihana Lenac Rovis
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5274 (2021)
Numerous viruses hijack cellular protein trafficking pathways to mediate cell entry or to rearrange membrane structures thereby promoting viral replication and antagonizing the immune response. Adaptor protein complexes (AP), which mediate protein so
Externí odkaz:
https://doaj.org/article/e1c0d78f15d8402396350c43389b610f
Publikováno v:
Food Technology and Biotechnology, Vol 43, Iss 4, Pp 379-388 (2005)
Comparison of three RT-PCR based methods: semi-quantitative, competitive and real--time RT-PCR for relative quantification of mRNA is presented. Aminopeptidase N expressed on human promyeloid HL-60 cell line, at basal and activated state, served as a
Externí odkaz:
https://doaj.org/article/7fc990bf243b4d54a70bf97da1cbcca2