Výsledky vyhledávání - "Andrej Tekel"

Lengthening the Guanidine–Aryl Linker of Phenylpyrimidinylguanidines Increases Their Potency as Inhibitors of FOXO3-Induced Gene Transcription

Autor: Klara Kohoutova, Vojtěch Dočekal, Michael J. Ausserlechner, Nora Kaiser, Andrej Tekel, Raju Mandal, Matej Horvath, Veronika Obsilova, Jan Vesely, Judith Hagenbuchner, Tomas Obsil

Publikováno v: ACS Omega. 7:34632-34646

Increased FOXO3 nuclear localization is involved in neuroblastoma chemoresistance and tumor angiogenesis. Accordingly, FOXO3 inhibition is a promising strategy for boosting antitumor immune responses and suppressing FOXO3-mediated therapy resistance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dda95a2e0a4642aa5af146779455398
https://doi.org/10.1021/acsomega.2c04613

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