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Akademický článek
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Autor:
Luka Rejc, Damijan Knez, Gabriela Molina-Aguirre, Alba Espargaró, Jerneja Kladnik, Anže Meden, Lana Blinc, Matic Lozinšek, Ross D. Jansen-van Vuuren, Matic Rogan, Bruno Aleksander Martek, Jernej Mlakar, Ana Dremelj, Andrej Petrič, Stanislav Gobec, Raimon Sabaté, Mara Bresjanac, Balazs Pinter, Janez Košmrlj
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116616- (2024)
Fluorescent probes are a powerful tool for imaging amyloid β (Aβ) plaques, the hallmark of Alzheimer’s disease (AD). Herein, we report the synthesis and comprehensive characterization of 21 novel probes as well as their optical properties and bin
Externí odkaz:
https://doaj.org/article/5dba3452cc3d4596945a7835ff379451
Publikováno v:
Molecules, Vol 21, Iss 3, p 267 (2016)
Naphthalene derivatives bearing electron-accepting and electron-donating groups at the 2,6-positions belong to the family of D-π-A push-pull dyes. It has been found that these compounds, e.g., 2-(1-(6-((2-(fluoro)ethyl)(methyl)amino)naphthalen-2-yl)
Externí odkaz:
https://doaj.org/article/58884d5a13d74c25819fa8710849b2d6
Autor:
Nagichettiar Satyamurthy, Sung-Cheng Huang, Graham B. Cole, Koon-Pong Wong, Janez Košmrlj, Jorge R. Barrio, Andrej Petrič, Jie Liu, Gary W. Small
Publikováno v:
Molecular Imaging and Biology. 21:25-34
Caution is warranted when in vitro results of biomarkers labeled with tritium were perfunctorily used to criticize in vivo data and conclusions derived with the same tracers labeled with positron emitters and positron emission tomography (PET). This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa70955ff4fd1738d9650a6b152209a0
https://doi.org/10.1007/s11307-018-1210-2
https://doi.org/10.1007/s11307-018-1210-2
Autor:
Graham B, Cole, Nagichettiar, Satyamurthy, Jie, Liu, Koon-Pong, Wong, Gary W, Small, Sung-Cheng, Huang, Janez, Košmrlj, Jorge R, Barrio, Andrej, Petrič
Publikováno v:
Molecular imaging and biology. 21(1)
Caution is warranted when in vitro results of biomarkers labeled with tritium were perfunctorily used to criticize in vivo data and conclusions derived with the same tracers labeled with positron emitters and positron emission tomography (PET). This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f9299cc10d4cc43e8b3b736a79d2b977
https://pubmed.ncbi.nlm.nih.gov/29855843
https://pubmed.ncbi.nlm.nih.gov/29855843
Autor:
Janez Košmrlj, Amalija Golobič, Andrej Petrič, Luka Rejc, Mara Bresjanac, Lojze Šmid, Črtomir Podlipnik, Jorge R. Barrio, Vladimir Kepe
Publikováno v:
Journal of medicinal chemistry. 60(21)
Deposition of aggregates of hyperphosphorylated tau protein is a hallmark of tauopathies like Alzheimer and many other neurodegenerative diseases. A sensitive and selective method of in vivo detection of tau-aggregate presence and distribution could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e187e065fca5c480df0fc2728caffac
https://pubmed.ncbi.nlm.nih.gov/28921979
https://pubmed.ncbi.nlm.nih.gov/28921979
Publikováno v:
Tetrahedron Letters. 55:1218-1221
In this work, we report the synthesis, X-ray structures, and optical properties of two DDNP analogs containing an unsaturated spacer inserted between the donor N,N-dimethylamino group and the naphthalene ring. The new compounds have longer distances
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9628295c4ca0a7dc388b3673fa07f82
https://doi.org/10.1016/j.tetlet.2014.01.002
https://doi.org/10.1016/j.tetlet.2014.01.002
Publikováno v:
Molecules
Molecules, Vol 21, Iss 3, p 267 (2016)
Molecules, vol. 21, no. 3, 267, 2016.
Molecules; Volume 21; Issue 3; Pages: 267
Molecules, Vol 21, Iss 3, p 267 (2016)
Molecules, vol. 21, no. 3, 267, 2016.
Molecules; Volume 21; Issue 3; Pages: 267
Naphthalene derivatives bearing electron-accepting and electron-donating groups at the 2,6-positions belong to the family of D-π-A push-pull dyes. It has been found that these compounds, e.g., 2-(1-(6-((2-(fluoro)ethyl)(methyl)amino)naphthalen-2-yl)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6dacd596ec14d1eceb863d5b248f5b
http://europepmc.org/articles/PMC6274339
http://europepmc.org/articles/PMC6274339
Autor:
Scott A. Johnson, Andrej Petrič, Nagichettiar Satyamurthy, Ying Li, Amalija Golobič, Hung V. Pham, Jie Liu, Jorge R. Barrio, Kendall N. Houk, Eric D. Agdeppa, Gyochang Keum, Gerald Timbol, Simon Čeh, Vladimir Kepe
Publikováno v:
Proceedings of the National Academy of Sciences. 109:16492-16497
The positron-emission tomography (PET) probe 2-(1-[6-[(2-fluoroethyl)(methyl)amino]-2-naphthyl]ethylidene) (FDDNP) is used for the noninvasive brain imaging of amyloid-β (Aβ) and other amyloid aggregates present in Alzheimer’s disease and other n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ca082ffb432bda1cd21001a0cee5ff
https://doi.org/10.1073/pnas.1214134109
https://doi.org/10.1073/pnas.1214134109
Autor:
Sung-Cheng Huang, Andrej Petrič, Gary W. Small, Jorge R. Barrio, Vladimir Kepe, Nagichettiar Satyamurthy
Publikováno v:
Accounts of Chemical Research. 42:842-850
Understanding the molecular mechanisms associated with the development of dementia is essential for designing successful interventions. Dementia, like cancer and cardiovascular disease, requires early detection to potentially arrest or prevent furthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7c407a9fa403bfb5f87df97855eced
https://doi.org/10.1021/ar800189x
https://doi.org/10.1021/ar800189x