Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Andrej Nikoshkov"'
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37429 (2012)
In the fields of proteomics, metabolic engineering and synthetic biology there is a need for high-throughput and reliable cloning methods to facilitate construction of expression vectors and genetic pathways. Here, we describe a new approach for soli
Externí odkaz:
https://doaj.org/article/6b08f8dde85e454b8bdb2569e17ca94e
Autor:
Mirco Martino, Rashid Mehmood, Honglei Zhao, Barbara A. Scholz, Andrej Nikoshkov, Emmanouil G. Sifakis, Carolina Diettrich Mallet de Lima, Anita Göndör, Ilyas Chachoua, Noriyuki Sumida, Deeksha Bhartiya, Rolf Ohlsson, Ilias Tzelepis
Publikováno v:
Nature Genetics. 51:1723-1731
WNT signaling activates MYC expression in cancer cells. Here we report that this involves an oncogenic super-enhancer-mediated tethering of active MYC alleles to nuclear pores to increase transcript export rates. As the decay of MYC transcripts is mo
Autor:
Ilyas Chachoua, Rolf Ohlsson, Emmanouil G. Sifakis, Ilias Tzelepis, Noriyuki Sumida, Deeksha Bhartiya, Rashid Mehmood, Mirco Martino, Andrej Nikoshkov, Anita Göndör, Honglei Zhao, Barbara A. Scholz, Carolina Diettrich Mallet de Lima
Publikováno v:
Nature Genetics. 52:1265-1265
Autor:
Barbara A, Scholz, Noriyuki, Sumida, Carolina Diettrich Mallet, de Lima, Ilyas, Chachoua, Mirco, Martino, Ilias, Tzelepis, Andrej, Nikoshkov, Honglei, Zhao, Rashid, Mehmood, Emmanouil G, Sifakis, Deeksha, Bhartiya, Anita, Göndör, Rolf, Ohlsson
Publikováno v:
Nature genetics. 51(12)
WNT signaling activates MYC expression in cancer cells. Here we report that this involves an oncogenic super-enhancer-mediated tethering of active MYC alleles to nuclear pores to increase transcript export rates. As the decay of MYC transcripts is mo
Autor:
Octavian Savu, Kerstin Brismar, Vivekananda Gupta Sunkari, Sergiu-Bogdan Catrina, Elisabete Forsberg, Andrej Nikoshkov
Publikováno v:
Karolinska Institutet
We have investigated promoter methylation of the Insr, Igf1 and Igf1r genes in skeletal and cardiac muscles of normal and diabetic db/db mice. No differences in Insr promoter methylation were found in the heart and skeletal muscles and no methylation
Autor:
Andrej Nikoshkov, Yasmin L. Hurd
Publikováno v:
Biochemical and Biophysical Research Communications. 351:383-386
Very limited is known about p53 expression in the normal mammalian brain and only few alternative splice variants have been reported thus far in human and rat peripheral tissues. Here, we detected eight new p53 transcripts in the human brain generate
Autor:
Yvonne Lundberg Giwercman, Åke Pousette, Birgitta Byström, Anna Wedell, Stefan Arver, Andrej Nikoshkov
Publikováno v:
Clinical Endocrinology. 54:827-834
OBJECTIVE: Resistance to androgens has been suggested as a possible cause of male infertility. This hypothesis is based mainly on binding studies in genital skin fibroblasts but the molecular evidence is sparse. DESIGN: Molecular studies of the andro
Autor:
Jacques Loiselet, Paolo Simi, Giampiero I. Baroncelli, Véronique Tardy, L. Cinquanta, Anna Wedell, Birgitta Byström, Silvano Bertelloni, Yvonne Lundberg Giwercman, Eliane Chouery, Jan Alm, André Mégarbané, Angelika Mohn, Kristina Lindsten, Georges Halaby, Åke Pousette, Eliane Khallouf, Jørgen Knudtzon, Simona Rossi, Michaela F. Hartmann, Andrej Nikoshkov, Michal Svoboda, Stefan A. Wudy, Giuseppe Saggese, Yves Morel, Francesco Chiarelli, Valérie Delague, Francesca Santilli, Noëlle Souraty
Publikováno v:
Hormone Research in Paediatrics. 53:104-108
Autor:
Yvonne Lundberg Giwercman, L. Cinquanta, Angelika Mohn, Anna Wedell, Michal Svoboda, Véronique Tardy, Silvano Bertelloni, Stefan A. Wudy, Birgitta Byström, Giuseppe Saggese, Eliane Chouery, Yves Morel, Eliane Khallouf, Paolo Simi, Åke Pousette, Jacques Loiselet, Jørgen Knudtzon, Kristina Lindsten, Georges Halaby, Giampiero I. Baroncelli, Jan Alm, Francesco Chiarelli, Andrej Nikoshkov, Valérie Delague, Francesca Santilli, André Mégarbané, Michaela F. Hartmann, Simona Rossi, Noëlle Souraty
Publikováno v:
Hormone Research in Paediatrics. 53:89-103
Autor:
Yvonne Lundberg Giwercman, Åke Pousette, Jørgen Knudtzon, Birgitta Byström, Andrej Nikoshkov, Anna Wedell, Jan Alm, Kristina Lindsten
Publikováno v:
Hormone Research in Paediatrics. 53:83-88
The androgen insensitivity syndrome is a disorder caused by deficient function of the androgen receptor, characterized by varying degrees of undermasculinization in karyotypic males. We have identified four mutations in the androgen receptor gene, in