HLA-G genetic diversity and evolutive aspects in worldwide populations

Autor: Erick C. Castelli, Bibiana S. de Almeida, Yara C. N. Muniz, Nayane S. B. Silva, Marília R. S. Passos, Andreia S. Souza, Abigail E. Page, Mark Dyble, Daniel Smith, Gabriela Aguileta, Jaume Bertranpetit, Andrea B. Migliano, Yeda A. O. Duarte, Marília O. Scliar, Jaqueline Wang, Maria Rita Passos-Bueno, Michel S. Naslavsky, Mayana Zatz, Celso Teixeira Mendes-Junior, Eduardo A. Donadi

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)

Abstract HLA-G is a promiscuous immune checkpoint molecule. The HLA-G gene presents substantial nucleotide variability in its regulatory regions. However, it encodes a limited number of proteins compared to classical HLA class I genes. We characteriz

Externí odkaz: https://doaj.org/article/4aa35f18b2a3467d92010afb84f174e1

MHC Variants Associated With Symptomatic Versus Asymptomatic SARS-CoV-2 Infection in Highly Exposed Individuals

Autor: Erick C. Castelli, Mateus V. de Castro, Michel S. Naslavsky, Marilia O. Scliar, Nayane S. B. Silva, Heloisa S. Andrade, Andreia S. Souza, Raphaela N. Pereira, Camila F. B. Castro, Celso T. Mendes-Junior, Diogo Meyer, Kelly Nunes, Larissa R. B. Matos, Monize V. R. Silva, Jaqueline Y. T. Wang, Joyce Esposito, Vivian R. Coria, Raul H. Bortolin, Mario H. Hirata, Jhosiene Y. Magawa, Edecio Cunha-Neto, Verônica Coelho, Keity S. Santos, Maria Lucia C. Marin, Jorge Kalil, Miguel Mitne-Neto, Rui M. B. Maciel, Maria Rita Passos-Bueno, Mayana Zatz

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Despite the high number of individuals infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) who develop coronavirus disease 2019 (COVID-19) symptoms worldwide, many exposed individuals remain asymptomatic and/or uninfected and ser

Externí odkaz: https://doaj.org/article/e2fb2fd00c7a451aa7e883d2e932e816

KIR2DL4 genetic diversity in a Brazilian population sample: implications for transcription regulation and protein diversity in samples with different ancestry backgrounds

Autor: Erick C. Castelli, Juliana Rodrigues Lara, Heloisa S. Andrade, Michelle A. Paz, Emiliana Weiss, Iane O. P. Porto, Celso T. Mendes-Junior, Andreia S. Souza, Nayane S. B. Silva, Camila Ferreira Bannwart Castro, Thálitta H. A. Lima, Rejane Maria Tommasini Grotto, Eduardo Antônio Donadi

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
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Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
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Made available in DSpace on 2021-06-25T10:53:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) KIR2DL4 is an important immune modulator expressed in natural killer cells;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd8ff1bcf948aceb8ed26876ea54dd9
https://doi.org/10.1007/s00251-021-01206-9

'Immunogenetics of resistance to SARS-CoV-2 infection in discordant couples'

Autor: Vivian R. Coria, Mayana Zatz, Mateus V. de Castro, Jaqueline T. W. Wang, Erick C. Castelli, Jorge Kalil, Raphaela Neto Pereira, Marilia O. Scliar, Larissa R. B. Matos, Maria Lucia C. Marin, Keity Souza Santos, Maria Rita Passos-Bueno, Verônica Coelho, Michel S Naslavsky, Kelly Nunes, Mario Hiroyuki Hirata, Heloisa S. Andrade, Diogo Meyer, Nayane S. B. Silva, Miguel Mitne Neto, Celso T. Mendes-Junior, Monize V. R. Silva, Andreia S. Souza, Camila Ferreira Bannwart Castro, Joyce Esposito, Rui M. B. Maciel, Edecio Cunha-Neto, Raul Hernandes Bortolin, Jhosiene Y. Magawa

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

BackgroundDespite the high number of individuals infected by SARS-CoV-2 who develop COVID-19 symptoms worldwide, many exposed individuals remain asymptomatic and/or stay uninfected. This could be explained by a combination of environmental (exposure,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd99fe361427d0fbcf75ffb80312b14c
https://doi.org/10.1101/2021.04.21.21255872

HLA-G genetic diversity and evolutive aspects in worldwide populations

Autor: Nayane S. B. Silva, Eduardo Antônio Donadi, Gabriela Aguileta, Bibiana Sgorla de Almeida, Marília R S Passos, Daniel J. Smith, Mayana Zatz, Andrea Bamberg Migliano, Yara Costa Netto Muniz, Jaqueline Wang, Abigail E. Page, Jaume Bertranpetit, Michel S Naslavsky, Marilia O. Scliar, Celso T. Mendes-Junior, Andreia S. Souza, Yeda Aparecida de Oliveira Duarte, Mark Dyble, Maria Rita Passos-Bueno, Erick C. Castelli

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Digital.CSIC. Repositorio Institucional del CSIC
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HLA-G is a promiscuous immune checkpoint molecule. The HLA-G gene presents substantial nucleotide variability in its regulatory regions. However, it encodes a limited number of proteins compared to classical HLA class I genes. We characterized the HL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eaf2a7ff641b098b6c78302883881f7