Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Andreia Neves Carvalho"'
Autor:
Sandra I. Anjo, Zhicheng He, Zohaib Hussain, Aruba Farooq, Alan McIntyre, Charles A. Laughton, Andreia Neves Carvalho, Mattéa J. Finelli
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 681 (2024)
Oxidation–reduction post-translational modifications (redox-PTMs) are chemical alterations to amino acids of proteins. Redox-PTMs participate in the regulation of protein conformation, localization and function, acting as signalling effectors that
Externí odkaz:
https://doaj.org/article/1adcba06898f4926b93ea5ec5a823183
Autor:
Carlota Leonardo-Sousa, Andreia Neves Carvalho, Romina A. Guedes, Pedro M. P. Fernandes, Natália Aniceto, Jorge A. R. Salvador, Maria João Gama, Rita C. Guedes
Publikováno v:
Molecules, Vol 27, Iss 7, p 2201 (2022)
Proteasome inhibitors have shown relevant clinical activity in several hematological malignancies, namely in multiple myeloma and mantle cell lymphoma, improving patient outcomes such as survival and quality of life, when compared with other therapie
Externí odkaz:
https://doaj.org/article/8685ca343ac848c2aa895341ddb40502
Autor:
Kristin Mayoral-Palarz, Andreia Neves-Carvalho, Sara Duarte-Silva, Daniela Monteiro-Fernandes, Patrícia Maciel, Kamran Khodakhah
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 8 (2022)
Spinocerebellar ataxia type 3 (SCA3) is an adult-onset, progressive ataxia. SCA3 presents with ataxia before any gross neuropathology. A feature of many cerebellar ataxias is aberrant cerebellar output that contributes to motor dysfunction. We examin
Externí odkaz:
https://doaj.org/article/1a36b8cb4e1641fdae0c96350de5b7d4
Autor:
Rui Lima, Eduardo D. Gomes, Jorge R. Cibrão, Luís A. Rocha, Rita C. Assunção-Silva, Cláudia S. Rodrigues, Andreia Neves-Carvalho, Susana Monteiro, António J. Salgado, Nuno A. Silva
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract Spinal cord injury (SCI) leads to dramatic impairments of motor, sensory, and autonomic functions of affected individuals. Following the primary injury, there is an increased release of glutamate that leads to excitotoxicity and further neur
Externí odkaz:
https://doaj.org/article/6381c90cd2744b65acae2876e1faad97
Autor:
Ana Bela Campos, Sara Duarte-Silva, Bruno Fernandes, Sofia Pereira das Neves, Fernanda Marques, Andreia Teixeira-Castro, Andreia Neves-Carvalho, Daniela Monteiro-Fernandes, Camila Cabral Portugal, Renato Socodato, Teresa Summavielle, António Francisco Ambrósio, João Bettencourt Relvas, Patrícia Maciel
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 237 (2022)
Microglia have been increasingly implicated in neurodegenerative diseases (NDs), and specific disease associated microglia (DAM) profiles have been defined for several of these NDs. Yet, the microglial profile in Machado–Joseph disease (MJD) remain
Externí odkaz:
https://doaj.org/article/bfa831bc12074691918231a72b6199b4
Autor:
Joana Sofia Correia, Andreia Neves-Carvalho, Bárbara Mendes-Pinheiro, Joel Pires, Fábio Gabriel Teixeira, Rui Lima, Susana Monteiro, Nuno André Silva, Carina Soares-Cunha, Sofia Cravino Serra, Sara Duarte-Silva, Andreia Teixeira-Castro, António José Salgado, Patrícia Maciel
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1754 (2021)
The low regeneration potential of the central nervous system (CNS) represents a challenge for the development of new therapeutic strategies for neurodegenerative diseases, including spinocerebellar ataxias. Spinocerebellar ataxia type 3 (SCA3)—or M
Externí odkaz:
https://doaj.org/article/692ddb03d70d40f8b32e77886b2612ce
Autor:
Duarte-Silva, Daniela Cunha-Garcia, Daniela Monteiro-Fernandes, Joana Sofia Correia, Andreia Neves-Carvalho, Ana Catarina Vilaça-Ferreira, Sónia Guerra-Gomes, João Filipe Viana, João Filipe Oliveira, Andreia Teixeira-Castro, Patrícia Maciel, Sara
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10606
Spinocerebellar ataxia type 3 (SCA3) is a rare neurodegenerative disease caused by an abnormal polyglutamine expansion within the ataxin-3 protein (ATXN3). This leads to neurodegeneration of specific brain and spinal cord regions, resulting in a prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::7de3600c9a036e42b4f484bf70693e2c
Autor:
Andreia Teixeira-Castro, Sofia Serra, Carina Soares-Cunha, Rui Lima, Joel Pires, Joana Sofia Correia, Patrícia Maciel, Susana Monteiro, Andreia Neves-Carvalho, Sara Duarte-Silva, Fábio G. Teixeira, António J. Salgado, Nuno A. Silva, Bárbara Mendes-Pinheiro
Publikováno v:
Biomedicines, Vol 9, Iss 1754, p 1754 (2021)
Biomedicines
Biomedicines; Volume 9; Issue 12; Pages: 1754
Biomedicines
Biomedicines; Volume 9; Issue 12; Pages: 1754
The low regeneration potential of the central nervous system (CNS) represents a challenge for the development of new therapeutic strategies for neurodegenerative diseases, including spinocerebellar ataxias. Spinocerebellar ataxia type 3 (SCA3)—or M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b8a495892ea1895dd592a23649b769
https://www.mdpi.com/2227-9059/9/12/1754
https://www.mdpi.com/2227-9059/9/12/1754
Autor:
Sofia Esteves, Sara Duarte-Silva, Luana Naia, Andreia Neves-Carvalho, Andreia Teixeira-Castro, Ana Cristina Rego, Anabela Silva-Fernandes, Patrícia Maciel
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141610 (2015)
Machado-Joseph disease (MJD) is an inherited neurodegenerative disease, caused by a CAG repeat expansion within the coding region of ATXN3 gene, and which currently lacks effective treatment. In this work we tested the therapeutic efficacy of chronic
Externí odkaz:
https://doaj.org/article/8961ab4612054489a68cfa73e0f680b5
Publikováno v:
Stem Cells International, Vol 2014 (2014)
The goal of this study was to determine and compare the effects of the secretome of mesenchymal stem cells (MSCs) isolated from human bone-marrow (BMSCs) and the Wharton jelly surrounding the vein and arteries of the umbilical cord (human umbilical c
Externí odkaz:
https://doaj.org/article/c89eae7be9b148e2ab0628dafddc3e42