Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andreia Machado Leopoldino"'
Autor:
Aline Faccioli Bodoni, Fernanda Borchers Coeli-Lacchini, Juliana Lourenço Gebenlian, Lays Martin Sobral, Cristiana Bernadelli Garcia, Wilson Araújo Silva, Kamila Chagas Peronni, Leandra Náira Zambelli Ramalho, Fernando Silva Ramalho, Ayrton C Moreira, Margaret de Castro, Andreia Machado Leopoldino, Sonir Roberto Rauber Antonini
Publikováno v:
The Journal of clinical endocrinology and metabolism.
Context Nicotinamide nucleotide transhydrogenase (NNT) acts as an antioxidant defense mechanism. NNT mutations cause familial glucocorticoid deficiency (FGD). How impaired oxidative stress disrupts adrenal steroidogenesis remains poorly understood. O
Autor:
Sonir Antonini, Aline Faccioli Bodoni, Fernanda Coeli-Lacchini, Juliana L Gebenlian, Ayrton C Moreira, Lucila L Elias, Wilson Araujo Silva Junior, Margaret Castro, Andreia Machado Leopoldino
Publikováno v:
Journal of the Endocrine Society. 6:A78-A79
Background The mitochondrial enzyme nicotinamide nucleotide transhydrogenase (NNT) is essential in the antioxidant defense mechanisms. In addition, adrenal cortex cells appear to require NNT for normal steroidogenesis. However, to date, the mechanism
Autor:
Gabriela Kelly da Silva, José Alcides Almeida de Arruda, Tatiana Fernandes Araújo Almeida, Sicília Rezende Oliveira, Paula Alves da Silva Rocha, Ricardo Alves Mesquita, Zenilda de Lourdes Cardeal, Helvécio Costa Menezes, Ivana Márcia Alves Diniz, Soraia Macari, Andréia Machado Leopoldino, Tarcília Aparecida Silva
Publikováno v:
Experimental and Molecular Pathology, Vol 134, Iss , Pp 104870- (2023)
Bisphenol A (BPA) is an endocrine-disrupting chemical with a potential role in endocrine cancers. However, the effects of BPA on the salivary glands have been barely explored. We investigated the impact of in vivo sub-chronic exposure to BPA and its
Externí odkaz:
https://doaj.org/article/c34cf0f477e4461c99b9dd2efaa01b44
Autor:
Isabella Bittencourt do Valle, Sicília Rezende Oliveira, Janine Mayra da Silva, Gabriela Tonini Peterle, Anna Clara Gregório Có, Sebastião Silvério Sousa-Neto, Elismauro Francisco Mendonça, José Alcides Almeida de Arruda, Natália Aparecida Gomes, Gabriel da Silva, Andréia Machado Leopoldino, Soraia Macari, Alexander Birbrair, Sandra Ventorin von Zeidler, Ivana Márcia Alves Diniz, Tarcília Aparecida Silva
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Pericytes are perivascular cells related to vessel structure and angiogenesis that can interact with neoplastic cells, interfering with cancer progression and outcomes. This study focused on the characterization of pericytes in oral squamous
Externí odkaz:
https://doaj.org/article/a6392e2da176465f8f543dd7efc9a47e
Autor:
Karina Stringhetta Padovani, Renata Nishida Goto, Lais Brigliadori Fugio, Cristiana Bernadelli Garcia, Vani Maria Alves, Maria Sol Brassesco, Lewis Joel Greene, Eduardo Magalhães Rego, Andréia Machado Leopoldino
Publikováno v:
FEBS Open Bio, Vol 11, Iss 7, Pp 2019-2032 (2021)
HnRNP K protein is a heterogeneous nuclear ribonucleoprotein which has been proposed to be involved in the leukemogenesis of acute promyelocytic leukemia (APL), as well as in differentiation induced by all‐trans retinoic acid (ATRA). We previously
Externí odkaz:
https://doaj.org/article/749f325fc18744e8838485c895753724
Autor:
Carolina Hassibe Thomé, Germano Aguiar Ferreira, Diego Antonio Pereira-Martins, Guilherme Augusto dos Santos, César Alexander Ortiz, Lucas Eduardo Botelho de Souza, Lays Martins Sobral, Cleide Lúcia Araújo Silva, Priscila Santos Scheucher, Cristiane Damas Gil, Andréia Machado Leopoldino, Douglas R. A. Silveira, Juan L. Coelho-Silva, Fabíola Traina, Luisa C. Koury, Raul A. M. Melo, Rosane Bittencourt, Katia Pagnano, Ricardo Pasquini, Elenaide C. Nunes, Evandro M. Fagundes, Ana Beatriz F. Gloria, Fábio Rodrigues Kerbauy, Maria de Lourdes Chauffaille, Armand Keating, Martin S. Tallman, Raul C. Ribeiro, Richard Dillon, Arnold Ganser, Bob Löwenberg, Peter Valk, Francesco Lo-Coco, Miguel A. Sanz, Nancy Berliner, Vitor Marcel Faça, Eduardo M. Rego
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Non-T cell activation linker (NTAL) is a lipid raft-membrane protein expressed by normal and leukemic cells and involved in cell signaling. In acute promyelocytic leukemia (APL), NTAL depletion from lipid rafts decreases cell viability throu
Externí odkaz:
https://doaj.org/article/1687378c1dd345e09a5c08f24c483459
Autor:
Verônica Soares Brauer, Fabiana Albani Zambuzi, Milena Sobral Espíndola, Marinaldo Pacífico Cavalcanti Neto, Morgana Kelly Borges Prado, Priscilla Mariane Cardoso, Luana Silva Soares, Leonardo Judson Galvao-Lima, Andréia Machado Leopoldino, Cristina Ribeiro de Barros Cardoso, Fabiani Gai Frantz
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 57 (2021)
Dehydroepiandrosterone (DHEA) is a steroid hormone secreted by the adrenal glands, gonads and brain. It is a precursor to sex hormones and also is known to have immune modulatory activity. However, little is known about the relationship between DHEA
Externí odkaz:
https://doaj.org/article/06937d099f6241979384a52294f4a015
Publikováno v:
Cells, Vol 9, Iss 3, p 581 (2020)
For decades, sphingolipids have been related to several biological functions such as immune system regulation, cell survival, and proliferation. Recently, it has been reported that sphingolipids could be biomarkers in cancer and in other human disord
Externí odkaz:
https://doaj.org/article/2898fcbeb1e04e2eb853d11b0a2cb48b
Autor:
Daniel Pecoraro Demarque, Rui Milton Patrício Silva, Leandro Figueiredo Santos, Andréia Machado Leopoldino, Enilza Maria Espreafico, Norberto Peporine Lopes
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 21, Iss 1 (2018)
The purpose of this contribution is to evaluate the cytotoxicity and apoptosis inducing ability of structurally diverse anthraquinones to establish a relationship between structure and toxicity. Besides the wide spread use of anthraquinones in pharma
Externí odkaz:
https://doaj.org/article/4386115ee406486d84562f5a810bb17d