Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Andreia C Lino"'
Autor:
Tobias Alexander, Thomas Dörner, Franziska Szelinski, Andreia C Lino, Karin Reiter, Annika Wiedemann, Sebastian Fuchs, Ana-Luisa Stefanski, Eva Vanessa Schrezenmeier, Hector Rincon-arevalo, Jacob Ritter, Marie Lettau, Duc Van Dang, Andreas P Frei
Publikováno v:
Lupus Science and Medicine, Vol 10, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/0c4e5e03657d4a2ca9407037720619d6
Publikováno v:
RMD Open, Vol 6, Iss 2 (2020)
Systemic lupus erythematosus (SLE) is characterised by numerous abnormalities in B lineage cells, including increased CD27++ plasmablasts/plasma cells, atypical CD27-IgD- B cells with increased CD95, spleen tyrosine kinase (Syk)++, CXCR5- and CXCR5+
Externí odkaz:
https://doaj.org/article/55c1484df68847cd96c93ee1014b79a5
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212525 (2019)
The bone marrow (BM) is, in addition to being the site of B cell development, a tissue that harbors long-lived plasma cells (PC), the cells that protect the body against foreign antigens by continuous production of antibodies. Nothing is known about
Externí odkaz:
https://doaj.org/article/9b6ca895048643fc8b494933cc5fe8a7
Autor:
Ana-Luisa Stefanski, Hector Rincon-Arevalo, Eva Schrezenmeier, Kirsten Karberg, Franziska Szelinski, Jacob Ritter, Yidan Chen, Christian Meisel, Bernd Jahrsdörfer, Carolin Ludwig, Hubert Schrezenmeier, Andreia C. Lino, Thomas Dörner
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundDurable vaccine-mediated immunity relies on the generation of long-lived plasma cells and memory B cells (MBCs), differentiating upon germinal center (GC) reactions. SARS-CoV-2 mRNA vaccination induces a strong GC response in healthy volunt
Externí odkaz:
https://doaj.org/article/b5aeff9220c347c9bc07d501ac810adc
Autor:
Van Duc Dang, Elodie Mohr, Franziska Szelinski, Tuan Anh Le, Jacob Ritter, Timo Hinnenthal, Ana-Luisa Stefanski, Eva Schrezenmeier, Soeren Ocvirk, Christian Hipfl, Sebastian Hardt, Qingyu Cheng, Falk Hiepe, Max Löhning, Thomas Dörner, Andreia C. Lino
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Antibody-secreting cells (ASCs) contribute to immunity through production of antibodies and cytokines. Identification of specific markers of ASC would allow selective targeting of these cells in several disease contexts. Here, we performed an unbiase
Externí odkaz:
https://doaj.org/article/aec1b76a408c4dc9b4c3c3b29da5a094
Autor:
Franziska Szelinski, Ana Luisa Stefanski, Eva Schrezenmeier, Hector Rincon‐Arevalo, Annika Wiedemann, Karin Reiter, Jacob Ritter, Marie Lettau, Van Duc Dang, Sebastian Fuchs, Andreas P. Frei, Tobias Alexander, Andreia C. Lino, Thomas Dörner
Publikováno v:
Arthritis & Rheumatology. 74:1556-1568
Autor:
Sarah Y. Weißenberg, Franziska Szelinski, Eva Schrezenmeier, Ana-Luisa Stefanski, Annika Wiedemann, Hector Rincon-Arevalo, Anna Welle, Annemarie Jungmann, Karl Nordström, Jörn Walter, Juliana Imgenberg-Kreuz, Gunnel Nordmark, Lars Rönnblom, Prathyusha Bachali, Michelle D. Catalina, Amrie C. Grammer, Peter E. Lipsky, Andreia C. Lino, Thomas Dörner
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Autoimmune diseases (AID) such as systemic lupus erythematosus (SLE), primary Sjögren's syndrome (pSS), and rheumatoid arthritis (RA) are chronic inflammatory diseases in which abnormalities of B cell function play a central role. Although it is wid
Externí odkaz:
https://doaj.org/article/d9ed2fdab4744e97827ac0c5501dd134
Autor:
Mariele Gatto, Annika Wiedemann, Nadja Nomovi, Karin Reiter, Eva Schrezenmeier, Thomas Rose, Franziska Szelinski, Andreia C. Lino, Sonia Valentino, Anna Ghirardello, Thomas Dörner, Andrea Doria
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Pentraxin3 (PTX3) is overexpressed in kidneys of patients developing lupus nephritis (LN). Active LN is associated with reduced anti-PTX3 antibodies. However, abnormalities of B cell differentiation against PTX3 have not been characterize
Externí odkaz:
https://doaj.org/article/9cf005332572471abdd500599e8ffda5
Autor:
Tuan Anh Le, Van Trung Chu, Andreia C. Lino, Eva Schrezenmeier, Christopher Kressler, Dania Hamo, Klaus Rajewsky, Thomas Dörner, Van Duc Dang
Publikováno v:
Molecular therapy. Nucleic acids. 30
Human B lymphocytes are attractive targets for immunotherapies in autoantibody-mediated diseases. Gene editing technologies could provide a powerful tool to determine gene regulatory networks regulating B cell differentiation into plasma cells, and i
Autor:
Franziska, Szelinski, Ana Luisa, Stefanski, Eva, Schrezenmeier, Hector, Rincon-Arevalo, Annika, Wiedemann, Karin, Reiter, Jacob, Ritter, Marie, Lettau, Van Duc, Dang, Sebastian, Fuchs, Andreas P, Frei, Tobias, Alexander, Andreia C, Lino, Thomas, Dörner
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.)REFERENCES. 74(9)
Altered composition of the B cell compartment in the pathogenesis of systemic lupus erythematosus (SLE) is characterized by expanded plasmablast and IgD-CD27- double-negative B cell populations. Previous studies showed that double-negative B cells re