Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andrei-José Petrescu"'
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Plant disease immunity heavily depends on the recognition of plant pathogens and the subsequent activation of downstream immune pathways. Nod-like receptors are often crucial in this process. Tsw, a Nod-like resistance gene from Capsicum chinense con
Externí odkaz:
https://doaj.org/article/e33c76ddfc954cf9b6a3ed7e483bfa4e
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Examination of a collection of over 80,000 Plant Nod-like receptors (NLRs) revealed an overwhelming sequence diversity underlying functional specificity of pathogen detection, signaling and cooperativity. The NLR canonical building blocks—CC/TIR/RP
Externí odkaz:
https://doaj.org/article/f3286fc0696d4dfba8e7988229f6f7d0
Publikováno v:
Frontiers in Plant Science, Vol 7 (2016)
Persistent infections by sedentary plant-parasitic nematodes are a major threat to important food crops all over the world. These round worms manipulate host plant cell morphology and physiology to establish sophisticated feeding structures. Key modi
Externí odkaz:
https://doaj.org/article/bcd96e2484b24f0598726638ed6ccf7e
Autor:
Nicolas Papadopoulos, Audrey Nédélec, Allison Derenne, Teodor Asvadur Şulea, Christian Pecquet, Ilyas Chachoua, Gaëlle Vertenoeil, Thomas Tilmant, Andrei-Jose Petrescu, Gabriel Mazzucchelli, Bogdan I. Iorga, Didier Vertommen, Stefan N. Constantinescu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
In myeloproliferative neoplasms, frameshift mutants of calreticulin turn into rogue cytokines by inducing constitutive activation of the Thrombopoietin Receptor (TpoR). Here, the authors define how mutant calreticulin acquires specificity for TpoR bi
Externí odkaz:
https://doaj.org/article/2608cc9507e54cfda715fbc3e86b7d63
Autor:
Gabriela N. Chiriţoiu, Cristian V.A. Munteanu, Teodor A. Şulea, Laurenţiu Spiridon, Andrei-Jose Petrescu, Camilla Jandus, Pedro Romero, Ştefana M. Petrescu
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107205- (2023)
Summary: The impact of the peptide amino acids side-chain modifications on the immunological recognition has been scarcely explored. We investigate here the effect of methionine oxidation on the antigenicity of the melanoma immunodominant peptide 369
Externí odkaz:
https://doaj.org/article/0ed781c5400041888ee8f60e4d5a3e85
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2023)
N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response. This is usually accomplished by a complex system o
Externí odkaz:
https://doaj.org/article/01edb566132448998d903f8d6a84d7b7
Publikováno v:
Journal of molecular graphicsmodelling. 25(1)
We present here a neural networks method designed to predict biological activity based on a local representation of the ligand. The compounds of the series are represented by a vector mapping for each of four substituent properties: volume, log P, di
Autor:
Tadeusz Wróblewski, Laurentiu Spiridon, Eliza Cristina Martin, Andrei-Jose Petrescu, Keri Cavanaugh, Maria José Truco, Huaqin Xu, Dariusz Gozdowski, Krzysztof Pawłowski, Richard W Michelmore, Frank L W Takken
Publikováno v:
PLoS Biology, Vol 16, Iss 12, p e2005821 (2018)
The ability to induce a defense response after pathogen attack is a critical feature of the immune system of any organism. Nucleotide-binding leucine-rich repeat receptors (NLRs) are key players in this process and perceive the occurrence of nonself-
Externí odkaz:
https://doaj.org/article/5e0c56211c954b07919831958f375eb9
Autor:
Hanan Sela, Laurentiu N. Spiridon, Haim Ashkenazi, Navreet K. Bhullar, Susanne Brunner, Andrei-Jose Petrescu, Tzion Fahima, Beat Keller, Tina Jordan
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 27, Iss 8, Pp 835-845 (2014)
The Pm3 gene confers resistance against wheat powdery mildew. Studies of Pm3 diversity have shown that Pm3 alleles isolated from southern populations of wild emmer wheat located in Lebanon, Jordan, Israel, and Syria are more diverse and more distant
Externí odkaz:
https://doaj.org/article/514e4e18ea0c491a88957616ff4cd639
Autor:
Jeyaraman Rajaraman, Dimitar Douchkov, Goetz Hensel, Francesca Stefanato, Anna Gordon, Nelzo Ereful, Octav Caldararu, Andrei-Jose Petrescu, Jochen Kumlehn, Lesley Ann Boyd, Patrick Schweizer
Publikováno v:
Frontiers in Plant Science, Vol 7 (2016)
Pattern recognition receptors (PRRs) belonging to the multigene family of receptor-like kinases (RLKs) are the sensing devices of plants for microbe- or pathogen-associated molecular patterns released from microbial organisms. Here we describe Rnr8 (
Externí odkaz:
https://doaj.org/article/1190bbd99a524bb0baf0a9552a2de059