A Secreted SPRY Domain-Containing Protein (SPRYSEC) from the Plant-Parasitic Nematode Globodera rostochiensis Interacts with a CC-NB-LRR Protein from a Susceptible Tomato

Autor: Sajid Rehman, Wiebe Postma, Tom Tytgat, Pjotr Prins, Ling Qin, Hein Overmars, Jack Vossen, Laurentiu-N. Spiridon, Andrei-J. Petrescu, Aska Goverse, Jaap Bakker, Geert Smant

Publikováno v: Molecular Plant-Microbe Interactions, Vol 22, Iss 3, Pp 330-340 (2009)

Esophageal gland secretions from nematodes are believed to include effectors that play important roles in plant parasitism. We have identified a novel gene family encoding secreted proteins specifically expressed in the dorsal esophageal gland of Glo

Externí odkaz: https://doaj.org/article/4bb94a0fe18642da8a6f5190cb4f19b1

Structure–function analysis of ZAR1 immune receptor reveals key molecular interactions for activity

Autor: Maël Baudin, Andrei J. Petrescu, Jennifer D. Lewis, Eliza C. Martin, Karl J. Schreiber

Publikováno v: The Plant Journal. 101:352-370

NLR (Nucleotide-binding [NB] Leucine-rich repeat [LRR] Receptor) proteins are critical for inducing immune responses in response to pathogen proteins, and must be tightly regulated to prevent spurious activation in the absence of a pathogen. The ZAR1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bf43ac4b515a2cda210d6a6f3b58f3
https://doi.org/10.1111/tpj.14547

Transposon Molecular Domestication and the Evolution of the RAG Recombinase

Autor: Tat Cheung Cheng, Andrei J. Petrescu, Anlong Xu, Yong Xiong, Pierre Pontarotti, Qingyi Lu, Yuhang Zhang, David G. Schatz, Marius Surleac, Jeffrey D. Mandell, Guangrui Huang

Publikováno v: Nature
Nature, 2019, 569 (7754), pp.79-84. ⟨10.1038/s41586-019-1093-7⟩
Trends Immunol
Nature, Nature Publishing Group, 2019, 569 (7754), pp.79-84. ⟨10.1038/s41586-019-1093-7⟩

Domestication of a transposon (a DNA sequence that can change its position in a genome) to give rise to the RAG1–RAG2 recombinase (RAG) and V(D)J recombination, which produces the diverse repertoire of antibodies and T cell receptors, was a pivotal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d475b25d5d9a4c97a78453102f196a0d
http://europepmc.org/articles/PMC6494689

Identification of RAG-like transposons in protostomes suggests their ancient bilaterian origin

Autor: Andrei J. Petrescu, Pierre Pontarotti, Louis Tsakou-Ngouafo, Celia Vicari, Eliza C. Martin, David G. Schatz

Publikováno v: Mobile DNA
Mobile DNA, BioMed Central, 2020, 11 (1), ⟨10.1186/s13100-020-00214-y⟩
Mobile DNA, Vol 11, Iss 1, Pp 1-20 (2020)
Mobile DNA, 2020, 11 (1), ⟨10.1186/s13100-020-00214-y⟩

Background V(D) J recombination is essential for adaptive immunity in jawed vertebrates and is initiated by the RAG1-RAG2 endonuclease. The RAG1 and RAG2 genes are thought to have evolved from a RAGL (RAG-like) transposon containing convergently-orie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a34313a8adc3164ef7390e52d6135e0
https://hal.archives-ouvertes.fr/hal-03047226

Evidence for an ancient bilaterian origin of the RAG-like transposon

Autor: Andrei J. Petrescu, Celia Vicari, Louis Tsakou Ngouafo, Pierre Pontarotti, Eliza C. Martin, David G. Schatz

Background V(D)J recombination is essential for adaptive immunity in jawed vertebrates and is initiated by the RAG1-RAG2 endonuclease. The RAG1 and RAG2 genes are thought to have evolved from a RAGL (RAG-like) transposon containing convergently-orien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c4bbb29d3ce445ce160bf07a7785d7
https://doi.org/10.21203/rs.2.19531/v1