Mechanism of Zn2+ and Ca2+ Binding to Human S100A1

Autor: Viktoriia E. Baksheeva, Andrei Yu. Roman, Claude Villard, François Devred, Deborah Byrne, Dahbia Yatoui, Arthur O. Zalevsky, Alisa A. Vologzhannikova, Andrey S. Sokolov, Sergei E. Permyakov, Andrey V. Golovin, Gary S. Shaw, Philipp O. Tsvetkov, Evgeni Yu. Zernii

Publikováno v: Biomolecules, Vol 11, Iss 12, p 1823 (2021)

S100A1 is a member of the S100 family of small ubiquitous Ca2+-binding proteins, which participates in the regulation of cell differentiation, motility, and survival. It exists as homo- or heterodimers. S100A1 has also been shown to bind Zn2+, but th

Externí odkaz: https://doaj.org/article/3e119f9307df406d953f6da5bad864a5

Functional Status of Neuronal Calcium Sensor-1 Is Modulated by Zinc Binding

Autor: Philipp O. Tsvetkov, Andrei Yu. Roman, Viktoriia E. Baksheeva, Aliya A. Nazipova, Marina P. Shevelyova, Vasiliy I. Vladimirov, Michelle F. Buyanova, Dmitry V. Zinchenko, Andrey A. Zamyatnin, François Devred, Andrey V. Golovin, Sergei E. Permyakov, Evgeni Yu. Zernii

Publikováno v: Frontiers in Molecular Neuroscience, Vol 11 (2018)

Neuronal calcium sensor-1 (NCS-1) protein is abundantly expressed in the central nervous system and retinal neurons, where it regulates many vital processes such as synaptic transmission. It coordinates three calcium ions by EF-hands 2-4, thereby tra

Externí odkaz: https://doaj.org/article/ecff2bbad9074ec5bbe551fbff15b38f

Mechanism of Zn

Autor: Viktoriia E, Baksheeva, Andrei Yu, Roman, Claude, Villard, François, Devred, Deborah, Byrne, Dahbia, Yatoui, Arthur O, Zalevsky, Alisa A, Vologzhannikova, Andrey S, Sokolov, Sergei E, Permyakov, Andrey V, Golovin, Gary S, Shaw, Philipp O, Tsvetkov, Evgeni Yu, Zernii

Publikováno v: Biomolecules

S100A1 is a member of the S100 family of small ubiquitous Ca2+-binding proteins, which participates in the regulation of cell differentiation, motility, and survival. It exists as homo- or heterodimers. S100A1 has also been shown to bind Zn2+, but th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::71317294142431a4efff31ccc08ee2d2
https://pubmed.ncbi.nlm.nih.gov/34944467

Zinc Binds to RRM2 Peptide of TDP-43

Autor: Françoise Guerlesquin, Rémy Puppo, Andrei Yu. Roman, Arthur O. Zalevsky, Régine Lebrun, Dahbia Yatoui, François Devred, Andrey V. Golovin, Philipp O. Tsvetkov

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 9080, p 9080 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2020, 21 (23), pp.9080. ⟨10.3390/ijms21239080⟩
International Journal of Molecular Sciences, MDPI, 2020, 21 (23), pp.9080. ⟨10.3390/ijms21239080⟩
Volume 21
Issue 23

Transactive response DNA and RNA binding protein 43 kDa (TDP-43) is a highly conserved heterogeneous nuclear ribonucleoprotein (hnRNP), which is involved in several steps of protein production including transcription and splicing. Its aggregates are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ed30a3e2a0888efaab469c092640a2
https://www.mdpi.com/1422-0067/21/23/9080

Generation of mouse lines with conditionally or constitutively inactivated Snca gene and Rosa26-stop-lacZ reporter located in cis on the mouse chromosome 6

Autor: Natalia Ninkina, A. A. Ustyugov, Galina Limorenko, Andrei Yu. Roman, Vladimir L. Buchman, Ekaterina A. Lysikova, T. V. Tarasova

Publikováno v: Transgenic Research

α-Synuclein is involved in many important molecular processes in neuronal cells and their synapses, and its malfunction has been linked to the development of Parkinson’s and certain other neurodegenerative diseases. Animal models allowing tightly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59936752ffa2c78ca252d3888adfa656
https://doi.org/10.1007/s11248-016-9995-8