Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Andrei V. Ougolkov"'
Autor:
Daniel D. Billadeau, Raul A. Urrutia, Doris N. Savoy, Martin E. Fernandez-Zapico, Andrei V. Ougolkov
Supplementary Materials from Glycogen Synthase Kinase-3β Participates in Nuclear Factor κB–Mediated Gene Transcription and Cell Survival in Pancreatic Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239f889f8a2a5828f1543a3eac16b92d
https://doi.org/10.1158/0008-5472.22364357
https://doi.org/10.1158/0008-5472.22364357
Autor:
Daniel D. Billadeau, Raul A. Urrutia, Doris N. Savoy, Martin E. Fernandez-Zapico, Andrei V. Ougolkov
Supplementary Figure 2 from Glycogen Synthase Kinase-3β Participates in Nuclear Factor κB–Mediated Gene Transcription and Cell Survival in Pancreatic Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b35be552c40691cc36eefad6240c83
https://doi.org/10.1158/0008-5472.22364360.v1
https://doi.org/10.1158/0008-5472.22364360.v1
Autor:
Daniel D. Billadeau, Raul A. Urrutia, Doris N. Savoy, Martin E. Fernandez-Zapico, Andrei V. Ougolkov
Supplementary Figure 1 from Glycogen Synthase Kinase-3β Participates in Nuclear Factor κB–Mediated Gene Transcription and Cell Survival in Pancreatic Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eaf448333a7e88762656b3c7267984d
https://doi.org/10.1158/0008-5472.22364363
https://doi.org/10.1158/0008-5472.22364363
Autor:
Daniel D. Billadeau, Raul A. Urrutia, Doris N. Savoy, Martin E. Fernandez-Zapico, Andrei V. Ougolkov
Recent studies using glycogen synthase kinase-3β (GSK-3β)–deficient mouse embryonic fibroblasts suggest that GSK-3β positively regulates nuclear factor κB (NFκB)–mediated gene transcription. Because NFκB is suggested to participate in cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e46e4821c766587195d8f12b96c9fb
https://doi.org/10.1158/0008-5472.c.6494156.v1
https://doi.org/10.1158/0008-5472.c.6494156.v1
Autor:
Alan P. Kozikowski, Sylvie Y. Blond, Franck Gallier, Andrei V. Ougolkov, Songpo Guo, Daniel D. Billadeau, Irina N. Gaisina, Toru Kurome, Denise L. Holzle, Doris N. Luchini, Ki Hwan Kim
Publikováno v:
Journal of Medicinal Chemistry. 52:1853-1863
Recent studies have demonstrated that glycogen synthase kinase 3beta (GSK-3beta) is overexpressed in human colon and pancreatic carcinomas, contributing to cancer cell proliferation and survival. Here, we report the design, synthesis, and biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b5e73cfb9faf8350c5e0a6466df322
https://doi.org/10.1021/jm801317h
https://doi.org/10.1021/jm801317h
Autor:
Suresh T. Chari, Thomas C. Smyrk, Suresh Pitchumoni, Supot Pongprasobchai, William R. Bamlet, Gloria M. Petersen, Mariza de Andrade, Andrei V. Ougolkov, Rahul Pannala
Publikováno v:
Pancreatology. 8:587-592
Objectives: In a matched analysis, we investigated clinical, histopathological, and survival characteristics of small (≤2 cm) pancreatic cancer (PaC) as compared to large PaC. Methods: From the Mayo pathology database, we identified 41 consecutive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a6ccf33b21b8509067af31c7e0cd69
https://doi.org/10.1159/000161009
https://doi.org/10.1159/000161009
Autor:
Yasuo Ohashi, Yutaka Takahashi, Hidekazu Kitakata, Kaname Yamashita, Hiroaki Nakazato, Toshinari Minamoto, Andrei V. Ougolkov, Kazuo Yasumoto, Katsuki Ito, Masayoshi Mai, Kazuhiko Omote
Publikováno v:
Diseases of the Colon & Rectum. 50:1182-1187
Protein-bound polysaccharide K is an immunotherapeutic agent that promotes apoptosis by inhibiting nuclear factor-kappaB activation in cancer cells. We previously showed that oncogenic beta-catenin activates nuclear factor-kappaB and inhibits apoptos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a2d170d8298d189a0bc0b136e86f9c
https://doi.org/10.1007/s10350-007-0291-9
https://doi.org/10.1007/s10350-007-0291-9
Autor:
Nancy D. Bone, Andrei V. Ougolkov, Neil E. Kay, Martin E. Fernandez-Zapico, Daniel D. Billadeau
Publikováno v:
Blood. 110:735-742
Chronic lymphocytic leukemia (CLL) is commonly defined as a disease of failed apoptosis of B cells and remains an incurable disease. The mechanism of resistance to apoptosis in CLL is complex and influenced by numerous factors, including nuclear fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cdd0d3a4928f7cd98dbd6b9439e92a
https://doi.org/10.1182/blood-2006-12-060947
https://doi.org/10.1182/blood-2006-12-060947
Autor:
Martin E. Fernandez-Zapico, Suresh T. Chari, Thomas C. Smyrk, Andrei V. Ougolkov, Daniel D. Billadeau, Vladimir Bilim
Publikováno v:
Clinical Cancer Research. 12:5074-5081
Purpose: We have shown recently that glycogen synthase kinase-3 (GSK-3) β regulates nuclear factor-κB (NF-κB)–mediated pancreatic cancer cell survival and proliferation in vitro. Our objective was to determine the localization of GSK-3β in panc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903a5aace324f1d9ca38144d4ac1eb1a
https://doi.org/10.1158/1078-0432.ccr-06-0196
https://doi.org/10.1158/1078-0432.ccr-06-0196
Publikováno v:
Future Oncology. 2:91-100
Glycogen synthase kinase (GSK)-3 has emerged as one of the most attractive therapeutic targets for the treatment of multiple neurological diseases, including Alzheimer's, stroke and bipolar disorders, as well as noninsulin-dependent diabetes mellitus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adb23636695694e047f9aa4767c2785
https://doi.org/10.2217/14796694.2.1.91
https://doi.org/10.2217/14796694.2.1.91