Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Andrei Surguchov"'
Autor:
Andrei Surguchov, Alexei A. Surguchev
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3899 (2024)
Epidemiological evidence points to an inverse association between Parkinson’s disease (PD) and almost all cancers except melanoma, for which this association is positive. The results of multiple studies have demonstrated that patients with PD are a
Externí odkaz:
https://doaj.org/article/641b15c732294478ac4974e4143abb64
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1215 (2023)
For a long time, studies of amyloidogenic proteins and peptides (amyloidogenic PPs) have been focused basically on their harmful properties and association with diseases. A vast amount of research has investigated the structure of pathogenic amyloids
Externí odkaz:
https://doaj.org/article/d557d112ddfc45dc879d446f7998ed43
Autor:
Andrei Surguchov
Publikováno v:
Brain Sciences, Vol 13, Iss 1, p 150 (2023)
Synucleinopathies are a group of neurodegenerative diseases with common pathological lesions associated with the excessive accumulation and abnormal intracellular deposition of toxic species of α-synuclein. The shared clinical features are chronic p
Externí odkaz:
https://doaj.org/article/223de067ea5f4abe855527dc851ecdc3
Autor:
Andrei Surguchov, Alexei Surguchev
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3241 (2022)
The synucleins are a family of natively unfolded (or intrinsically unstructured) proteins consisting of α-, β-, and γ-synuclein involved in neurodegenerative diseases and cancer. The current number of publications on synucleins has exceeded 16.000
Externí odkaz:
https://doaj.org/article/d94fbf8343844d7fadb274c4740e4dee
Autor:
Marzieh Mojbafan, Shirzadeh Tina, Fatemeh Zafarghandi Motlagh, Andrei Surguchov, Yalda Nilipour, Sirous Zeinali
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 12, Pp n/a-n/a (2019)
Abstract Background Dysferlinopathies are a group of autosomal recessive limb‐girdle muscular dystrophies (LGMDs) caused by mutations in DYSF (#603,009). This gene encodes a transmembrane protein called dysferlin. Since there are few reports on Ira
Externí odkaz:
https://doaj.org/article/2841dd7f7c8d4fea84813a1340f7526c
Publikováno v:
Biomolecules, Vol 11, Iss 5, p 624 (2021)
Synucleinopathies are a group of neurodegenerative diseases characterized by the accumulation of α-synuclein aggregates in neurons, nerve fibers or glial cells. Three main types of diseases belong to the synucleinopathies: Parkinson’s disease, dem
Externí odkaz:
https://doaj.org/article/2a35c43ec12a4324bfb2733011aeb1a3
Autor:
Andrei Surguchov
Publikováno v:
Cells, Vol 10, Iss 2, p 407 (2021)
Parkinson’s disease (PD) is the second most common neurodegenerative disease, afflicting ~10 million people worldwide. Although several genes linked to PD are currently identified, PD remains primarily an idiopathic disorder. Neuronal protein α-sy
Externí odkaz:
https://doaj.org/article/7d4b3d41519f47bcb64afe9e09bb35cb
Autor:
Fatemeh N. Emamzadeh, Andrei Surguchov
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Parkinson’s disease (PD) is a progressive neurodegenerative disorder caused mainly by lack of dopamine in the brain. Dopamine is a neurotransmitter involved in movement, motivation, memory, and other functions; its level is decreased in PD brain as
Externí odkaz:
https://doaj.org/article/eab1d8fa74214b95816e1222bfd02b73
Autor:
Andrei Surguchov
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2801 (2020)
α-Synuclein is a naturally unfolded protein which easily aggregates and forms toxic inclusions and deposits. It is associated with several neurodegenerative diseases, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multipl
Externí odkaz:
https://doaj.org/article/b359fefda0624063ab9cc4093101d594
Autor:
Alexei A. Surguchev, Andrei Surguchov
Publikováno v:
Brain Sciences, Vol 10, Iss 2, p 121 (2020)
Identification of genetic markers of a human disease, which is generally sporadic, may become an essential tool for the investigation of its molecular mechanisms. The role of ABCA7 in Alzheimer’s disease (AD) was discovered less than ten years ago
Externí odkaz:
https://doaj.org/article/7cda0c69527a495b9c0b835f78429f97