Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Andrei S. Zolotukhin"'
Autor:
Andrei S. Zolotukhin, Jenifer Bear, Michelle Mitchell, Guy R. Pilkington, Stuart F. J. Le Grice, George N. Pavlakis, Barbara K. Felber, Katarzyna J. Purzycka, Michal Legiewicz, Hiroaki Uranishi
Publikováno v:
Journal of Biological Chemistry. 285:42097-42104
Retrovirus replication requires specialized transport mechanisms to export genomic mRNA from the nucleus to the cytoplasm of the infected cell. This regulation is mediated by a combination of viral and/or cellular factors that interact with cis-actin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef65983f51913566ab7037dcb12f3070
https://doi.org/10.1074/jbc.m110.182840
https://doi.org/10.1074/jbc.m110.182840
Autor:
Barbara K. Felber, Andrei S. Zolotukhin, Hiroaki Uranishi, George N. Pavlakis, Jenifer Bear, Susan Lindtner
Publikováno v:
Nucleic Acids Research
The conserved mRNA export receptor NXF1 (Mex67 in yeast) assembles with messenger ribonucleoproteins (mRNP) in the nucleus and guides them through the nuclear pore complex into the cytoplasm. The DEAD family RNA helicase Dbp5 is essential for nuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7100077c200ce527adb4a0af5bd8e79
https://doi.org/10.1093/nar/gkp782
https://doi.org/10.1093/nar/gkp782
Autor:
Barbara K. Felber, Viraj Kulkarni, Cristina Bergamaschi, George N. Pavlakis, Gen-Mu Zhang, Andrei S. Zolotukhin, Candido Alicea, Rashmi Jalah, Margherita Rosati
Publikováno v:
J Immunol
The two known isoforms of IL-15 contain either a long signal peptide (LSP) or a short signal peptide (SSP), and are produced by alternatively spliced transcripts. It has been proposed that SSP IL-15 remains exclusively intracellular, and its function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23ccae9fce5786a1c5d298079ef8391
https://doi.org/10.4049/jimmunol.0900693
https://doi.org/10.4049/jimmunol.0900693
Autor:
Barbara K. Felber, Susan Lindtner, Gen Mu Zhang, Jenifer Bear, Andrei S. Zolotukhin, Hiroaki Uranishi, Søren Warming, George N. Pavlakis, Neal G. Copeland, Nancy A. Jenkins
Publikováno v:
The Journal of Biological Chemistry
The human SPEN family proteins SHARP, RBM15/OTT1, and RBM15B/OTT3 share the structural domain architecture but show distinct functional properties. Here, we examined the function of OTT3 and compared it with its paralogues RBM15 and SHARP. We found t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8331deb42c2b6c701d57f8cb63b4ab75
http://europepmc.org/articles/PMC2758010
http://europepmc.org/articles/PMC2758010
Autor:
Andrei S. Zolotukhin, Martina Samiotaki, Hiroaki Uranishi, Jenifer Bear, George Panayotou, George N. Pavlakis, Viraj Kulkarni, Sergey Smulevitch, Barbara K. Felber, Susan Lindtner
Publikováno v:
Journal of Biological Chemistry. 281:36915-36928
Retroviruses/retroelements provide tools enabling the identification and dissection of basic steps for post-transcriptional regulation of cellular mRNAs. The RNA transport element (RTE) identified in mouse retrotransposons is functionally equivalent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e92126835ac99f51624f01c055a675
https://doi.org/10.1074/jbc.m608745200
https://doi.org/10.1074/jbc.m608745200
Autor:
Andrei S. Zolotukhin, Wei Tan, Jenifer Bear, Barbara K. Felber, Sergey Smulevitch, Susan Lindtner, Irina Tretyakova
Publikováno v:
Nucleic Acids Research
TAP/hNXF1 is a key factor that mediates general cellular mRNA export from the nucleus, and its orthologs are structurally and functionally conserved from yeast to humans. Metazoans encode additional proteins that share homology and domain organizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f5f06bf094f376de00585de04c0ce2
https://doi.org/10.1093/nar/gki706
https://doi.org/10.1093/nar/gki706
Autor:
James G. Patton, Ivan N. Shatsky, Andrei S. Zolotukhin, Rui Peng, Daniel Michalowski, Barbara K. Felber, Sergey Smulevitch, Jenifer Bear, Abdulmaged M. Traish
Publikováno v:
Molecular and Cellular Biology. 23:6618-6630
Human immunodeficiency virus type 1 (HIV) gag/pol and env mRNAs contain cis-acting regulatory elements (INS) that impair stability, nucleocytoplasmic transport, and translation by unknown mechanisms. This downregulation can be counteracted by the vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cc467e042776eaf6876930e0fcf1a0
https://doi.org/10.1128/mcb.23.18.6618-6630.2003
https://doi.org/10.1128/mcb.23.18.6618-6630.2003
Publikováno v:
RNA. 6:1762-1772
Human TAP and Saccharomyces cerevisiae Mex67p belong to a family of proteins that mediate mRNA export. Computer searches identified previously two Caenorhabditis elegans genes, C15H11.3 and C115H11.6, that encode putative homologs of hTAP and Mex67p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f2989ee0d35b57ce62d45dedea9865
https://doi.org/10.1017/s1355838200000832
https://doi.org/10.1017/s1355838200000832
Autor:
Jenifer Bear, Carlos Tabernero, Wei Tan, Barbara K. Felber, Andrei S. Zolotukhin, Eric A. Hudson
Publikováno v:
Molecular and Cellular Biology. 19:6306-6317
The nuclear export of the unspliced type D retrovirus mRNA depends on the cis-acting constitutive transport RNA element (CTE) that has been shown to interact with the human TAP (hTAP) protein promoting the export of the CTE-containing mRNAs. We repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cae62050a15bea5915e2e49496305e3
https://doi.org/10.1128/mcb.19.9.6306
https://doi.org/10.1128/mcb.19.9.6306
Publikováno v:
Journal of Biological Chemistry. 272:11356-11360
We identified a region in the human Ran GTPase-binding protein RanBP1 that shares similarities to the nuclear export signal of the inhibitor of the cAMP-dependent protein kinase. Mutational analysis confirmed that this region is responsible for the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055c1eb2beeb9ea55474f2a0544a432e
https://doi.org/10.1074/jbc.272.17.11356
https://doi.org/10.1074/jbc.272.17.11356