Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Andrei S. Halavaty"'
Autor:
Nicole C. Woitowich, Andrei S. Halavaty, Patricia Waltz, Christopher Kupitz, Joseph Valera, Gregory Tracy, Kevin D. Gallagher, Elin Claesson, Takanori Nakane, Suraj Pandey, Garrett Nelson, Rie Tanaka, Eriko Nango, Eiichi Mizohata, Shigeki Owada, Kensure Tono, Yasumasa Joti, Angela C. Nugent, Hardik Patel, Ayesha Mapara, James Hopkins, Phu Duong, Dorina Bizhga, Svetlana E. Kovaleva, Rachael St. Peter, Cynthia N. Hernandez, Wesley B. Ozarowski, Shatabdi Roy-Chowdhuri, Jay-How Yang, Petra Edlund, Heikki Takala, Janne Ihalainen, Jennifer Brayshaw, Tyler Norwood, Ishwor Poudyal, Petra Fromme, John C. H. Spence, Keith Moffat, Sebastian Westenhoff, Marius Schmidt, Emina A. Stojković
Publikováno v:
IUCrJ, Vol 5, Iss 5, Pp 619-634 (2018)
Phytochromes are red-light photoreceptors that were first characterized in plants, with homologs in photosynthetic and non-photosynthetic bacteria known as bacteriophytochromes (BphPs). Upon absorption of light, BphPs interconvert between two states
Externí odkaz:
https://doaj.org/article/a56c4f1741084155bcfa230773aaee98
Autor:
Joseph D. Lykins, Ekaterina V. Filippova, Andrei S. Halavaty, George Minasov, Ying Zhou, Ievgeniia Dubrovska, Kristin J. Flores, Ludmilla A. Shuvalova, Jiapeng Ruan, Kamal El Bissati, Sarah Dovgin, Craig W. Roberts, Stuart Woods, Jon D. Moulton, Hong Moulton, Martin J. McPhillie, Stephen P. Muench, Colin W. G. Fishwick, Elisabetta Sabini, Dhanasekaran Shanmugam, David S. Roos, Rima McLeod, Wayne F. Anderson, Huân M. Ngô
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Toxoplasma gondii, an Apicomplexan parasite, causes significant morbidity and mortality, including severe disease in immunocompromised hosts and devastating congenital disease, with no effective treatment for the bradyzoite stage. To address this, we
Externí odkaz:
https://doaj.org/article/7419bf5aa70142e9901dc7a9d33f4a08
Autor:
Babu A. Manjasetty, Andrei S. Halavaty, Chi-Hao Luan, Jerzy Osipiuk, Rory Mulligan, Keehwan Kwon, Wayne F. Anderson, Andrzej Joachimiak
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 537-539 (2016)
The fluorescence-based thermal shift (FTS) data presented here include Table S1 and Fig. S1, and are supplemental to our original research article describing detailed structural, FTS, and fluorescence polarization analyses of the Salmonella enterica
Externí odkaz:
https://doaj.org/article/9cbe70c01d364d55ac4b931b8f4c5a14
Publikováno v:
Journal of Structural Biology. 202:175-181
Many bacteria require L-rhamnose as a key cell wall component. This sugar is transferred to the cell wall using an activated donor dTDP-L-rhamnose, which is produced by the dTDP-L-rhamnose biosynthetic pathway. We determined the crystal structure of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad45ed32f0b157c85318c45848654f3d
https://doi.org/10.1016/j.jsb.2018.01.006
https://doi.org/10.1016/j.jsb.2018.01.006
Autor:
George Minasov, Misty L. Kuhn, Wayne F. Anderson, Aleksander Shornikov, Ha Tran, Andrei S. Halavaty, Jennifer Macias
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 73:644-650
Bacillus anthracis is the causative agent of the deadly disease Anthrax. Its use in bioterrorism and its ability to re-emerge have brought renewed interest in this organism. B. anthracis is a Gram-positive bacterium that adds L-rhamnose to its cell-w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fdaab4df56a98cce0cc90e020bae28
https://doi.org/10.1107/s2053230x17015746
https://doi.org/10.1107/s2053230x17015746
Autor:
Wayne F. Anderson, Andrzej Joachimiak, Babu A. Manjasetty, Jerzy Osipiuk, Chi Hao Luan, Keehwan Kwon, Andrei S. Halavaty, Rory Mulligan
Publikováno v:
Journal of Structural Biology. 194:18-28
Multidrug transcription regulator AcrR from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 belongs to the tetracycline repressor family, one of the largest groups of bacterial transcription factors. The crystal structure of dimeric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa626f015a1fdefed378285366a3e3d
https://doi.org/10.1016/j.jsb.2016.01.008
https://doi.org/10.1016/j.jsb.2016.01.008
Autor:
Hyunjin Kim, Karla J. Satchell, Brett Geissler, Andrei S. Halavaty, Mallory J. Agard, Alan R. Hauser, Gregory H. Tyson, Wayne F. Anderson, Wonhwa Cho
Publikováno v:
Journal of Biological Chemistry. 290:2919-2937
Bacterial toxins require localization to specific intracellular compartments following injection into host cells. In this study, we examined the membrane targeting of a broad family of bacterial proteins, the patatin-like phospholipases. The best cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19a8a1e347bd62b7c3b7fd28dae2021
https://doi.org/10.1074/jbc.m114.611251
https://doi.org/10.1074/jbc.m114.611251
Autor:
Aleksander Shornikov, Ha Tran, Jennifer Macias, Andrei S. Halavaty, George Minasov, Wayne F. Anderson, Misty L. Kuhn
The exosporium layer of Bacillus anthracis spores is rich in L-rhamnose, a common bacterial cell-wall component, which often contributes to the virulence of pathogens by increasing their adherence and immune evasion. The biosynthetic pathway used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76f767389b8ccd0ad470308bddb7c22
https://europepmc.org/articles/PMC5713671/
https://europepmc.org/articles/PMC5713671/
Autor:
Jesi Lee, Andrei S. Halavaty, Wayne F. Anderson, George Minasov, Misty L. Kuhn, Jackson T. Baumgartner
Publikováno v:
Acta crystallographica. Section F, Structural biology communications. 73(Pt 11)
L-Rhamnose is a ubiquitous bacterial cell-wall component. The biosynthetic pathway for its precursor dTDP-L-rhamnose is not present in humans, which makes the enzymes of the pathway potential drug targets. In this study, the three-dimensional structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7948f22f9ccab6590c0c5a4aa8454133
https://pubmed.ncbi.nlm.nih.gov/29095156
https://pubmed.ncbi.nlm.nih.gov/29095156
Autor:
Nancy E. Freitag, Andrei S. Halavaty, Samuel H. Light, Mijoon Lee, Kiran V. Mahasenan, Wayne F. Anderson, Shahriar Mobashery, Laty A. Cahoon, Bill Boggess
Publikováno v:
Structure (London, England : 1993). 25(2)
Active in the aqueous cellular environment where a massive excess of water is perpetually present, enzymes that catalyze the transfer of an electrophile to a non-water nucleophile (transferases) require specific strategies to inhibit mechanistically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615c0280b2f4cf10b2c61107b2193322
https://pubmed.ncbi.nlm.nih.gov/28089449
https://pubmed.ncbi.nlm.nih.gov/28089449