Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Andrei O Zalensky"'
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52944 (2012)
The intranuclear positioning of chromosomes (CHRs) is a well-documented fact; however, mechanisms directing such ordering remain unclear. Unlike somatic cells, human spermatozoa contain distinct spatial markers and have asymmetric nuclei which make t
Externí odkaz:
https://doaj.org/article/6ab6243caf404c3ba4c27e643db81596
Publikováno v:
AIMS Genetics, Vol 5, Iss 2, Pp 113-123 (2018)
AIMS Genetics
AIMS Genetics
Chromosome positioning in sperm nucleus may have a functional significance by influencing the sequence of post-fertilization events. In this study we present data on preferential locations of chromosomes 1, 29 and X in Bos taurus spermatozoa. Here we
Autor:
Irina A. Zalenskaya, Igor B. Nazarov, Andrei O. Zalensky, Luda S. Shlyakhtenko, Yuri L. Lyubchenko
Publikováno v:
Systems Biology in Reproductive Medicine. 54:37-46
In human spermatozoa, 15-20% of histones are retained in the nucleus to coexist with protamines. Hypothetically, nucleohistone regions of sperm chromatin mark DNA sequences for distinctive processing during fertilization and early embryogenesis. The
Autor:
Mahmood Morshedi, Stephanie Singleton, Andrei O. Zalensky, Gustavo F. Doncel, Irina A. Zalenskaya
Publikováno v:
Human Reproduction. 22:743-750
Background The compaction of human sperm chromatin is the result of replacement of approximately 85% of histones with protamines. Germ-line testis/sperm-specific histone 2B (TSH2B) has been detected in only approximately 30% of mature spermatozoa. It
Autor:
Kangling Zhang, Maria Svetlova, Dmitri Churikov, Joseph S. Siino, Andrei O. Zalensky, E. Morton Bradbury, Arunas Gineitis
Publikováno v:
Genomics. 84:745-756
Testis-specific histones are synthesized and accumulated at specific stages of mammalian spermatogenesis. Their proposed functions range from facilitation of the replacement of somatic histones by protamines to epigenetic control of gene transcriptio
Autor:
Andrei O. Zalensky, Irina A. Zalenskaya, E. Morton Bradbury, Joseph S. Siino, Nikolai V. Tomilin, Peter M. Yau, Arunas Gineitis
Publikováno v:
Journal of Biological Chemistry. 277:43474-43480
Human sperm, unlike the sperm of other mammals, contain replacement histones with unknown biological functions. Here, we report the identification of the novel human gene coding for a testis/sperm-specific histone H2B (hTSH2B). This variant histone i
Publikováno v:
Biology of Reproduction. 62:340-346
Telomere DNA at the physical termini of chromosomes forms a single-stranded 3' overhang. In lower eukaryotes, e.g., ciliated protozoa, this DNA extension is capped by specific proteins that have been structurally and functionally characterized. Much
Publikováno v:
Molecular Reproduction and Development. 51:98-104
An increase in the length of telomeres in human sperm compared to somatic cells has long been noted and considered within a popular hypothesis involving telomere shortening and cell aging. In the present study we determined telomere length in two spe
Publikováno v:
Sperm Chromatin for the Researcher ISBN: 9781461484585
Sperm Chromatin ISBN: 9781441917812
Sperm Chromatin ISBN: 9781441917812
Similar to interphase chromosomes, mammalian supercompact and genetically inactive sperm chromatin is arranged in non-overlapping chromosome territories. Recent works demonstrate that chromosome territories in sperm have defined and nonrandom intranu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9a1fbb97ac26bde57dcdace102f096
https://doi.org/10.1007/978-1-4614-8459-2_4
https://doi.org/10.1007/978-1-4614-8459-2_4
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e52944 (2012)
PLoS ONE, Vol 7, Iss 12, p e52944 (2012)
The intranuclear positioning of chromosomes (CHRs) is a well-documented fact; however, mechanisms directing such ordering remain unclear. Unlike somatic cells, human spermatozoa contain distinct spatial markers and have asymmetric nuclei which make t