Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andrei M. Kornilov"'
Autor:
Kramer James Bernard, M.C. Holt, Stephen Douglas Barrett, Chi S. Ho, James Paul O'malley, Thomas A. Owen, Adam Uzieblo, Fred L. Ciske, A.J. Stein, Joseph Michael Colombo, María Inés Morano, Bradlee David Germain, Andrei M. Kornilov
Publikováno v:
Journal of Medicinal Chemistry. 62:4731-4741
A series of small-molecule full agonists of the prostaglandin E2 type 4 (EP4) receptor have been generated and evaluated for binding affinity and cellular potency. KMN-80 and its gem-difluoro analog KMN-159 possess high selectivity relative to other
Autor:
Cindy L. Moran, Andrei M. Kornilov, Anna Radominska-Pandya, Laura P. James, Vi-Huyen Le, William D. Wessinger, James B. Kramer, Larry D. Bratton, Paul D. Kennedy, Jeffery H. Moran, Paul J. Dobrowolski, Amy L. Smedley, Felisia D. Lackey, Paul L. Prather, Gregory W. Endres, Krishna C. Chimalakonda, Suzanne N. Owen, William E. Fantegrossi, Fred Lawrence Ciske
Publikováno v:
Analytical Chemistry. 83:4228-4236
'K2/SPICE' products are commonly laced with aminoalkylindole synthetic cannabinoids (i.e., JWH-018 and JWH-073) and are touted as ‘legal’ marijuana substitutes. Here we validate a liquid chromatography tandem mass spectrometry (LC-MS/MS) methsod
Publikováno v:
Synthesis. :2589-2596
The stereocontrolled synthesis of N-protected (2S,3R)-2-amino-3-fluoroundecanoic and (3R)-3-amino-2,2-difluoroundecanoic acids, as representative examples, from commercially available optically pure (R)-2,3-O-isopropylideneglyceraldehyde is described
Publikováno v:
Tetrahedron: Asymmetry. 6:199-206
The difluorides obtained in the reaction of DAST with appropriate ketones could serve as a suitable starting materials for the selective incorporation of CF 2 -group into the molecules of the unsaturated chiral natural compounds. As an example, stere
Publikováno v:
ChemInform. 26
The difluorides obtained in the reaction of DAST with appropriate ketones could serve as a suitable starting materials for the selective incorporation of CF 2 -group into the molecules of the unsaturated chiral natural compounds. As an example, stere