Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Andrei M Mikheev"'
Publikováno v:
Molecular Oncology, Vol 18, Iss 3, Pp 517-527 (2024)
TWIST1 (TW) is a pro‐oncogenic basic helix–loop–helix (bHLH) transcription factor and promotes the hallmark features of malignancy (e.g., cell invasion, cancer cell stemness, and treatment resistance), which contribute to poor prognoses of glio
Externí odkaz:
https://doaj.org/article/9e6adc00e2824614969ee219bf8002b8
Autor:
Xuefeng Ren, Jessica C Graham, Lichen Jing, Andrei M Mikheev, Yuan Gao, Jenny Pan Lew, Hong Xie, Andrea S Kim, Xiuling Shang, Cynthia Friedman, Graham Vail, Ming Zhu Fang, Yana Bromberg, Helmut Zarbl
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e70930 (2013)
Rat strains differ dramatically in their susceptibility to mammary carcinogenesis. On the assumption that susceptibility genes are conserved across mammalian species and hence inform human carcinogenesis, numerous investigators have used genetic link
Externí odkaz:
https://doaj.org/article/95b43a43dbe84d18999ebbd5d660546d
Autor:
Vittorio Cristini, Elvin Blanco, Robert C. Rostomily, Andrei M. Mikheev, Zhihui Wang, Giulia Brachi, Mauro Ferrari, Gianluca Ciardelli, Clara Mattu, Javier Ruiz-Ramírez, Prashant Dogra
Publikováno v:
Nanoscale
Intratumoral drug delivery is a promising approach for the treatment of glioblastoma multiforme (GBM).
Intratumoral drug delivery is a promising approach for the treatment of glioblastoma multiforme (GBM). However, drug washout remains a major c
Intratumoral drug delivery is a promising approach for the treatment of glioblastoma multiforme (GBM). However, drug washout remains a major c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4eb756c4b7ee13b2a9c4f9168a0d95b
https://pubmed.ncbi.nlm.nih.gov/33237080
https://pubmed.ncbi.nlm.nih.gov/33237080
Autor:
Liza J. Severs, Lei Huang, Jeanette Schwensen, Stephen T. C. Wong, Svetlana A. Mikheeva, Nathan D. Price, Cory C. Funk, José L. McFaline-Figueroa, Cole Trapnell, Andrei M. Mikheev, Robert C. Rostomily
Publikováno v:
Molecular Oncology, Vol 12, Iss 7, Pp 1188-1202 (2018)
Molecular Oncology
Molecular Oncology
TWIST1 (TW) is a bHLH transcription factor (TF) and master regulator of the epithelial-to-mesenchymal transition (EMT). In vitro, TW promotes mesenchymal change, invasion, and self-renewal in glioblastoma (GBM) cells. However, the potential therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6e54ce6cb62331afb881f5d92e4ecd
https://doaj.org/article/57b3afd2b53f44d68b2c689df8d63308
https://doaj.org/article/57b3afd2b53f44d68b2c689df8d63308
Publikováno v:
Oncotarget
Twist1 is a master regulator of epithelial mesenchymal transition and carcinoma metastasis. Twist1 has also been associated with increased malignancy of human glioma. However, the impact of inhibiting Twist1 on tumorigenicity has not been characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0004400be709e75ed1206984391f4d18
https://doi.org/10.18632/oncotarget.22593
https://doi.org/10.18632/oncotarget.22593
Autor:
Robert C. Rostomily, K. Castro, A. D. Rodriguez, Raymond J. Monnat, Z. Dereli-Korkut, R. Lin, Albert Folch, Lisa F. Horowitz, Andrei M. Mikheev
Publikováno v:
NPJ Precision Oncology
npj Precision Oncology, Vol 4, Iss 1, Pp 1-15 (2020)
npj Precision Oncology, Vol 4, Iss 1, Pp 1-15 (2020)
Current methods to assess the drug response of individual human cancers are often inaccurate, costly, or slow. Functional approaches that rapidly and directly assess the response of patient cancer tissue to drugs or small molecules offer a promising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c96026d31ca21432007d5e663475bc2
https://pubmed.ncbi.nlm.nih.gov/32435696
https://pubmed.ncbi.nlm.nih.gov/32435696
Autor:
Soniya Vaidya, Phillip M. Gerk, Kenneth L. Audus, Abner N. Nyandege, Marie V. St-Pierre, Andrei M. Mikheev, Kelly E. Desino, Jashvant D. Unadkat, Anand A. Joshi
Publikováno v:
Pharmaceutical Research. 33:2847-2878
The human placenta fulfills a variety of essential functions during prenatal life. Several ABC transporters are expressed in the human placenta, where they play a role in the transport of endogenous compounds and may protect the fetus from exogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f9f50c6a7851be98b0346300ea6249
https://doi.org/10.1007/s11095-016-2028-8
https://doi.org/10.1007/s11095-016-2028-8
Autor:
Sam Frankel, Rob G. Oxford, Donald E. Born, John R. Silber, Thomas C. Manning, Mari Tokita, Yoshito Kosai, Barbara Carnemolla, Andrew D. Trister, Samuel Emerson, Carolina Parada, Andrei M. Mikheev, Deok Ho Kim, Robert C. Rostomily, Kathleen R. Tozer-Fink, Svetlana A. Mikheeva
Publikováno v:
Neuro-Oncology. 17:372-382
Periostin is a matricellular fascilin-like protein that was first described as a component of periodontal ligaments.1 Subsequently, periostin has been shown to have critical functions in development, pathologic fibrosis, and cancer biology (reviewed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfb3b1c8e5a5c1b0f18389dedef8163
https://doi.org/10.1093/neuonc/nou161
https://doi.org/10.1093/neuonc/nou161
Autor:
Jing Zhang, Alejandro Wolf-Yadlin, Lei Huang, Mari Tokita, Andrei M. Mikheev, Svetlana A. Mikheeva, Sung Yun Jung, Antrix Jain, Robert C. Rostomily, Naze G. Avci, Stephen J. Tapscott, Nathan D. Camp
Publikováno v:
Cancers
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1392 (2019)
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1392 (2019)
Diffuse invasion into adjacent brain matter by glioblastoma (GBM) is largely responsible for their dismal prognosis. Previously, we showed that the TWIST1 (TW) bHLH transcription factor and its regulated gene periostin (POSTN) promote invasive phenot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc51a8a9bcc34c6924c4758307155ee
https://doi.org/10.3390/cancers11091392
https://doi.org/10.3390/cancers11091392
Autor:
Kristin R. Swanson, Robert C. Rostomily, Susan Christine Massey, Philip J. Horner, Elizabeth A. Stoll, Andrei M. Mikheev, Jurate Lasiene, Behnum A. Habibi
Publikováno v:
Stem Cells. 29:2005-2017
Although new neurons are produced in the subventricular zone (SVZ) of the adult mammalian brain, fewer functional neurons are produced with increasing age. The age-related decline in neurogenesis has been attributed to a decreased pool of neural prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d5fec171e8261854f689c5ed7df998
https://doi.org/10.1002/stem.747
https://doi.org/10.1002/stem.747