Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Andrei Loas"'
Autor:
Peiyuan Zhang, Xiyun Ye, John C. K. Wang, Corey L. Smith, Silvino Sousa, Andrei Loas, Dan L. Eaton, Magdalena Preciado López, Bradley L. Pentelute
Publikováno v:
JACS Au, Vol 4, Iss 4, Pp 1334-1344 (2024)
Externí odkaz:
https://doaj.org/article/29e685a0575f4dd6be9c5db9ae67c024
Autor:
Alex J. Callahan, Satish Gandhesiri, Tara L. Travaline, Rahi M. Reja, Lia Lozano Salazar, Stephanie Hanna, Yen-Chun Lee, Kunhua Li, Olena S. Tokareva, Jean-Marie Swiecicki, Andrei Loas, Gregory L. Verdine, John H. McGee, Bradley L. Pentelute
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Widespread adoption of mirror-image biological systems presents difficulties in accessing the requisite D-protein substrates. In particular, mirror-image phage display has the potential for high-throughput generation of biologically stable m
Externí odkaz:
https://doaj.org/article/d0273f3cd1884e53b769531534d77eaf
Autor:
Chengxi Li, Genwei Zhang, Somesh Mohapatra, Alex J. Callahan, Andrei Loas, Rafael Gómez‐Bombarelli, Bradley L. Pentelute
Publikováno v:
Advanced Science, Vol 9, Iss 34, Pp n/a-n/a (2022)
Abstract Peptide nucleic acids (PNAs) are potential antisense therapies for genetic, acquired, and viral diseases. Efficiently selecting candidate PNA sequences for synthesis and evaluation from a genome containing hundreds to thousands of options ca
Externí odkaz:
https://doaj.org/article/48f8867a3109422590dbda03779410d5
Autor:
Genwei Zhang, Joseph S. Brown, Anthony J. Quartararo, Chengxi Li, Xuyu Tan, Stephanie Hanna, Sarah Antilla, Amanda E. Cowfer, Andrei Loas, Bradley L. Pentelute
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-10 (2022)
Angiotensin converting enzyme 2 (ACE2) has been identified as a cardiovascular disease biomarker and the primary receptor utilized by SARS-CoV-2, but developing serum-stable, selective and high-affinity binders for this target is challenging. Here, t
Externí odkaz:
https://doaj.org/article/148c1454126b4e02903048591db85c6f
Autor:
Chengxi Li, Alex J. Callahan, Kruttika S. Phadke, Bryan Bellaire, Charlotte E. Farquhar, Genwei Zhang, Carly K. Schissel, Alexander J. Mijalis, Nina Hartrampf, Andrei Loas, David E. Verhoeven, Bradley L. Pentelute
Publikováno v:
ACS Central Science, Vol 8, Iss 2, Pp 205-213 (2021)
Externí odkaz:
https://doaj.org/article/4cacfea2bd9d40439c92d254f7ca4bea
Autor:
Eva M. López-Vidal, Carly K. Schissel, Somesh Mohapatra, Kamela Bellovoda, Chia-Ling Wu, Jenna A. Wood, Annika B. Malmberg, Andrei Loas, Rafael Gómez-Bombarelli, Bradley L. Pentelute
Publikováno v:
JACS Au, Vol 1, Iss 11, Pp 2009-2020 (2021)
Externí odkaz:
https://doaj.org/article/cd02882331b944c98c796971667fec2e
Autor:
Chengxi Li, Alex J. Callahan, Mark D. Simon, Kyle A. Totaro, Alexander J. Mijalis, Kruttika-Suhas Phadke, Genwei Zhang, Nina Hartrampf, Carly K. Schissel, Ming Zhou, Hong Zong, Gunnar J. Hanson, Andrei Loas, Nicola L. B. Pohl, David E. Verhoeven, Bradley L. Pentelute
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
PMOs (phosphorodiamidate morpholino oligomers) have huge potential for antisense therapy but complex and slow synthesis limits application. Here, the authors report the development of automated flow synthesis methods which reduce nucleobase coupling
Externí odkaz:
https://doaj.org/article/b0ad40ceaf224d3c88e0a5f7d5670117
Autor:
Somesh Mohapatra, Nina Hartrampf, Mackenzie Poskus, Andrei Loas, Rafael Gómez-Bombarelli, Bradley L. Pentelute
Publikováno v:
ACS Central Science, Vol 6, Iss 12, Pp 2277-2286 (2020)
Externí odkaz:
https://doaj.org/article/21eafd6862b94d47be0a39d45b86291b
Autor:
Choi-Fong Cho, Charlotte E. Farquhar, Colin M. Fadzen, Benjamin Scott, Pei Zhuang, Niklas von Spreckelsen, Andrei Loas, Nina Hartrampf, Bradley L. Pentelute, Sean E. Lawler
Publikováno v:
Cancers, Vol 14, Iss 9, p 2207 (2022)
Background: Glioblastoma (GBM) is the most common and deadliest malignant primary brain tumor, contributing significant morbidity and mortality among patients. As current standard-of-care demonstrates limited success, the development of new efficacio
Externí odkaz:
https://doaj.org/article/204cc3cf62da43318d7d82a4404bb012
Autor:
Azin Saebi, Joseph S. Brown, Victoria M. Marando, Nina Hartrampf, Nicole M. Chumbler, Stephanie Hanna, Mackenzie Poskus, Andrei Loas, Laura L. Kiessling, Deborah T. Hung, Bradley L. Pentelute
Publikováno v:
ACS Chemical Biology. 18:518-527