Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Andrei L. Lomize"'
Publikováno v:
Protein Sci
Cellular protrusions, invaginations, and many intracellular organelles have strongly curved membrane regions. Transmembrane and peripheral membrane proteins that induce, sense, or stabilize such regions cannot be properly fitted into a single flat bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7c885da9be53493ced1fae46af5fc8
https://doi.org/10.1002/pro.4219
https://doi.org/10.1002/pro.4219
Autor:
Andrei L. Lomize, Kevin A. Schnitzer, Spencer C. Todd, Stanislav Cherepanov, Carlos Outeiral, Charlotte M. Deane, Irina D. Pogozheva
Publikováno v:
Protein science : a publication of the Protein Society. 31(5)
The Membranome database provides comprehensive structural information on single-pass (i.e., bitopic) membrane proteins from six evolutionarily distant organisms, including protein-protein interactions, complexes, mutations, experimental structures, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d8c0e49b37b30aecd6676347291b4b
https://pubmed.ncbi.nlm.nih.gov/35481632
https://pubmed.ncbi.nlm.nih.gov/35481632
Autor:
Irina D. Pogozheva, Grant A. Armstrong, Lingyang Kong, Timothy J. Hartnagel, Carly A. Carpino, Stephen E. Gee, Danielle M. Picarello, Amanda S. Rubin, Jumin Lee, Soohyung Park, Andrei L. Lomize, Wonpil Im
Publikováno v:
Journal of chemical information and modeling. 62(4)
We present a comparative all-atom molecular dynamics simulation study of 18 biomembrane systems with lipid compositions corresponding to eukaryotic, bacterial, and archaebacterial membranes together with three single-component lipid bilayers. A total
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c78812edcb6162fb362247b1d605a9
https://pubmed.ncbi.nlm.nih.gov/35167752
https://pubmed.ncbi.nlm.nih.gov/35167752
Publikováno v:
Biophysical Journal. 122:283a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d3004ebbd0b251971e794a97b571bde
https://doi.org/10.1016/j.bpj.2022.11.1608
https://doi.org/10.1016/j.bpj.2022.11.1608
Publikováno v:
Biophysical Journal. 121:224a-225a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9faaebc70b6189afac2b92aa1d11d040
https://doi.org/10.1016/j.bpj.2021.11.1606
https://doi.org/10.1016/j.bpj.2021.11.1606
Publikováno v:
Journal of chemical information and modeling. 61(6)
The Folding of Membrane-Associated Peptides (FMAP) method was developed for modeling α-helix formation by linear peptides in micelles and lipid bilayers. FMAP 2.0 identifies locations of α-helices in the amino acid sequence, generates their three-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3d1844ba966700782f56066d831e80
https://pubmed.ncbi.nlm.nih.gov/34029472
https://pubmed.ncbi.nlm.nih.gov/34029472
Autor:
Kanjana Madhongsa, Supaluk Pasan, Onanong Phophetleb, Sawinee Nasompag, Sompong Thammasirirak, Sakda Daduang, Suwimol Taweechaisupapong, Andrei L Lomize, Rina Patramanon
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 6, p e2267 (2013)
Burkholderia pseudomallei is a category B agent that causes Melioidosis, an acute and chronic disease with septicemia. The current treatment regimen is a heavy dose of antibiotics such as ceftazidime (CAZ); however, the risk of a relapse is possible.
Externí odkaz:
https://doaj.org/article/c749490a521f4a6798644e4ca261a3ed
Publikováno v:
Journal of molecular biology. 432(11)
Estimating energies of transmembrane (TM) α-helix association is essential for understanding folding of membrane proteins and formation of their functional assemblies. A new physics-based method was developed and implemented in the TMPfold web serve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1217c8225790a79dc52ced040376514
https://pubmed.ncbi.nlm.nih.gov/31682836
https://pubmed.ncbi.nlm.nih.gov/31682836
Autor:
Konstantin Golobokov, Mitchell B. LaFaive, Irina D. Pogozheva, Andrei L. Lomize, Jacob M. Hage, Kevin A. Schnitzer, Alexander C. Forsyth
The PerMM web server and database were developed for quantitative analysis and visualization of passive translocation of bioactive molecules across lipid membranes. The server is the first physics-based web tool that calculates membrane binding energ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f477bd93e855a70cc0700073e1e682e0
https://europepmc.org/articles/PMC6781619/
https://europepmc.org/articles/PMC6781619/
Autor:
Andrei L. Lomize, Irina D. Pogozheva
Assessment of permeability is a critical step in the drug development process for selection of drug candidates with favorable ADME properties. We have developed a novel physics-based method for fast computational modeling of passive permeation of div
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18452af7e599a2f3dbc27d1cdb0a44e
https://europepmc.org/articles/PMC6756154/
https://europepmc.org/articles/PMC6756154/