Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Andrei L Osterman"'
Autor:
Sara Calhoun, Magdalena Korczynska, Daniel J Wichelecki, Brian San Francisco, Suwen Zhao, Dmitry A Rodionov, Matthew W Vetting, Nawar F Al-Obaidi, Henry Lin, Matthew J O'Meara, David A Scott, John H Morris, Daniel Russel, Steven C Almo, Andrei L Osterman, John A Gerlt, Matthew P Jacobson, Brian K Shoichet, Andrej Sali
Publikováno v:
eLife, Vol 7 (2018)
The functions of most proteins are yet to be determined. The function of an enzyme is often defined by its interacting partners, including its substrate and product, and its role in larger metabolic networks. Here, we describe a computational method
Externí odkaz:
https://doaj.org/article/fd3b096083a24d889b6a4ac902e9dcb6
Comparative genomics and functional analysis of rhamnose catabolic pathways and regulons in Bacteria
Autor:
Irina A Rodionova, Xiaoqing eLi, Vera eThiel, Sergey eStolyar, Krista eStanton, James K Fredrickson, Donald A Bryant, Andrei L Osterman, Aaron A Best, Dmitry A Rodionov
Publikováno v:
Frontiers in Microbiology, Vol 4 (2013)
L-rhamnose (L-Rha) is a deoxy-hexose sugar commonly found in nature. L-Rha catabolic pathways were previously characterized in various bacteria including Escherichia coli. Nevertheless, homology searches failed to recognize all the genes for the comp
Externí odkaz:
https://doaj.org/article/904b7f3f8fe04de89f0b6b509854446a
Autor:
Dmitry A Rodionov, Irina A Rodionova, Xiaoqing eLi, Dmitry A Ravcheev, Yekaterina eTarasova, Vasiliy A Portnoy, Karsten eZengler, Andrei L Osterman
Publikováno v:
Frontiers in Microbiology, Vol 4 (2013)
Hyperthermophilic bacteria from the Thermotogales lineage can produce hydrogen by fermenting a wide range of carbohydrates. Previous experimental studies identified a large fraction of genes committed to carbohydrate degradation and utilization in th
Externí odkaz:
https://doaj.org/article/1b1b32414001456fa574b9c9c7c2225c
Autor:
Brian P Anton, Yi-Chien Chang, Peter Brown, Han-Pil Choi, Lina L Faller, Jyotsna Guleria, Zhenjun Hu, Niels Klitgord, Ami Levy-Moonshine, Almaz Maksad, Varun Mazumdar, Mark McGettrick, Lais Osmani, Revonda Pokrzywa, John Rachlin, Rajeswari Swaminathan, Benjamin Allen, Genevieve Housman, Caitlin Monahan, Krista Rochussen, Kevin Tao, Ashok S Bhagwat, Steven E Brenner, Linda Columbus, Valérie de Crécy-Lagard, Donald Ferguson, Alexey Fomenkov, Giovanni Gadda, Richard D Morgan, Andrei L Osterman, Dmitry A Rodionov, Irina A Rodionova, Kenneth E Rudd, Dieter Söll, James Spain, Shuang-Yong Xu, Alex Bateman, Robert M Blumenthal, J Martin Bollinger, Woo-Suk Chang, Manuel Ferrer, Iddo Friedberg, Michael Y Galperin, Julien Gobeill, Daniel Haft, John Hunt, Peter Karp, William Klimke, Carsten Krebs, Dana Macelis, Ramana Madupu, Maria J Martin, Jeffrey H Miller, Claire O'Donovan, Bernhard Palsson, Patrick Ruch, Aaron Setterdahl, Granger Sutton, John Tate, Alexander Yakunin, Dmitri Tchigvintsev, Germán Plata, Jie Hu, Russell Greiner, David Horn, Kimmen Sjölander, Steven L Salzberg, Dennis Vitkup, Stanley Letovsky, Daniel Segrè, Charles DeLisi, Richard J Roberts, Martin Steffen, Simon Kasif
Publikováno v:
PLoS Biology, Vol 11, Iss 8, p e1001638 (2013)
Externí odkaz:
https://doaj.org/article/08400167d9dc4fa29d1dc69cd0f6756f
Autor:
Lucia Cialabrini, Silverio Ruggieri, Marat D Kazanov, Leonardo Sorci, Francesca Mazzola, Giuseppe Orsomando, Andrei L Osterman, Nadia Raffaelli
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65595 (2013)
We have recently identified the enzyme NMN deamidase (PncC), which plays a key role in the regeneration of NAD in bacteria by recycling back to the coenzyme the pyridine by-products of its non redox consumption. In several bacterial species, PncC is
Externí odkaz:
https://doaj.org/article/9e960e1018be4ea4a8dc015b7ecab28d
Autor:
Jessica De Ingeniis, Marat D Kazanov, Konstantin Shatalin, Mikhail S Gelfand, Andrei L Osterman, Leonardo Sorci
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39115 (2012)
NAD is a ubiquitous and essential metabolic redox cofactor which also functions as a substrate in certain regulatory pathways. The last step of NAD synthesis is the ATP-dependent amidation of deamido-NAD by NAD synthetase (NADS). Members of the NADS
Externí odkaz:
https://doaj.org/article/731b41a7a80f44d2b22087d43c19079e
Autor:
Jessica De Ingeniis, Boris Ratnikov, Adam D Richardson, David A Scott, Pedro Aza-Blanc, Surya K De, Marat Kazanov, Maurizio Pellecchia, Ze'ev Ronai, Andrei L Osterman, Jeffrey W Smith
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45190 (2012)
Proline metabolism is linked to hyperprolinemia, schizophrenia, cutis laxa, and cancer. In the latter case, tumor cells tend to rely on proline biosynthesis rather than salvage. Proline is synthesized from either glutamate or ornithine; both are conv
Externí odkaz:
https://doaj.org/article/d83c1930472b4511a15b6ff8fb037355
Publikováno v:
Critical Reviews in Biochemistry and Molecular Biology. 57:562-584
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7433c2e7e18add53b4af8244a28dbf17
https://doi.org/10.1080/10409238.2023.2182272
https://doi.org/10.1080/10409238.2023.2182272
Autor:
Miriam N. Ojima, Lin Jiang, Aleksandr A. Arzamasov, Keisuke Yoshida, Toshitaka Odamaki, Jinzhong Xiao, Aruto Nakajima, Motomitsu Kitaoka, Junko Hirose, Tadasu Urashima, Toshihiko Katoh, Aina Gotoh, Douwe van Sinderen, Dmitry A. Rodionov, Andrei L. Osterman, Mikiyasu Sakanaka, Takane Katayama
Publikováno v:
The ISME Journal. 16(9):2265-2279
Bifidobacteria are among the first colonizers of the infant gut, and human milk oligosaccharides (HMOs) in breastmilk are instrumental for the formation of a bifidobacteria-rich microbiota. However, little is known about the assembly of bifidobacteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5496fd3650fc22fee8356f31728e8b3f
http://hdl.handle.net/2433/275900
http://hdl.handle.net/2433/275900
Autor:
Alexandra V. Vylegzhanina, Ivan A. Bespalov, Ksenia A. Novototskaya-Vlasova, Brandon M. Hall, Anatoli S. Gleiberman, Han Yu, Olga V. Leontieva, Katerina I. Leonova, Oleg V. Kurnasov, Andrei L. Osterman, Grace K. Dy, Alexey A. Komissarov, Elena Vasilieva, Jeff Gehlhausen, Akiko Iwasaki, Christine B. Ambrosone, Takemasa Tsuji, Junko Matsuzaki, Kunle Odunsi, Ekaterina L. Andrianova, Andrei V. Gudkov
LINE-1 (L1), the most abundant family of autonomous retrotransposons occupying over 17% of human DNA, is epigenetically silenced in normal tissues but frequently derepressed in cancer, suggesting that L1-encoded proteins may act as tumor-associated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8477abcfdeea873bdfbc1aaddff4cbf4
https://doi.org/10.1101/2023.02.03.526997
https://doi.org/10.1101/2023.02.03.526997
