Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Andrei I Ivanov"'
Autor:
Fariba Rezaee, Terri J Harford, Debra T Linfield, Ghaith Altawallbeh, Ronald J Midura, Andrei I Ivanov, Giovanni Piedimonte
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181876 (2017)
Airway epithelium forms a barrier to the outside world and has a crucial role in susceptibility to viral infections. Cyclic adenosine monophosphate (cAMP) is an important second messenger acting via two intracellular signaling molecules: protein kina
Externí odkaz:
https://doaj.org/article/4f2db74f6e8c4c87a25dd640d4e0acd4
Autor:
Susana Lechuga, Armando Marino-Melendez, Austin Davis, Ajay Zalavadia, Afshin Khan, Michelle S. Longworth, Andrei I. Ivanov
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The actin cytoskeleton regulates the integrity and repair of epithelial barriers by mediating the assembly of tight junctions (TJs), and adherens junctions (AJs), and driving epithelial wound healing. Actin filaments undergo a constant turnover guide
Externí odkaz:
https://doaj.org/article/90752bd185b04a1eb931a662eeb18208
Publikováno v:
eLife, Vol 5 (2016)
Polo-like kinase 1 (PLK1) is a key cell cycle regulator implicated in the development of various cancers, including prostate cancer. However, the functions of PLK1 beyond cell cycle regulation remain poorly characterized. Here, we report that PLK1 ov
Externí odkaz:
https://doaj.org/article/04021b9f4eb44042be60ab919c21d034
Autor:
Samuel P Wanner, Kyoko Yoshida, Vladimir A Kulchitsky, Andrei I Ivanov, Kazuyuki Kanosue, Andrej A Romanovsky
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75733 (2013)
Systemic inflammatory response syndrome is associated with either fever or hypothermia, but the mechanisms responsible for switching from one to the other are unknown. In experimental animals, systemic inflammation is often induced by bacterial lipop
Externí odkaz:
https://doaj.org/article/4a2637d374d94af29fbda9e3dec322b3
Autor:
Nayden G Naydenov, Bryan Brown, Gianni Harris, Michael R Dohn, Victor M Morales, Somesh Baranwal, Albert B Reynolds, Andrei I Ivanov
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34320 (2012)
Tight junctions (TJs) and adherens junctions (AJs) are key determinants of the structure and permeability of epithelial barriers. Although exocytic delivery to the cell surface is crucial for junctional assembly, little is known about the mechanisms
Externí odkaz:
https://doaj.org/article/3633add115e7484e9a6b0d78ec4776b5
Autor:
Andrei I Ivanov, Moshe Bachar, Brian A Babbin, Robert S Adelstein, Asma Nusrat, Charles A Parkos
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e658 (2007)
The integrity and function of the epithelial barrier is dependent on the apical junctional complex (AJC) composed of tight and adherens junctions and regulated by the underlying actin filaments. A major F-actin motor, myosin II, was previously implic
Externí odkaz:
https://doaj.org/article/8bfa21258ada4fa8b2c15b2319df07c9
Autor:
Alexandre A Steiner, Andrei I Ivanov, Jordi Serrats, Hiroshi Hosokawa, Allison N Phayre, Jared R Robbins, Jennifer L Roberts, Shigeo Kobayashi, Kiyoshi Matsumura, Paul E Sawchenko, Andrej A Romanovsky
Publikováno v:
PLoS Biology, Vol 4, Iss 9, p e284 (2006)
All phases of lipopolysaccharide (LPS)-induced fever are mediated by prostaglandin (PG) E2. It is known that the second febrile phase (which starts at approximately 1.5 h post-LPS) and subsequent phases are mediated by PGE2 that originated in endothe
Externí odkaz:
https://doaj.org/article/9de30b9a4eb44907b2d4085fa8e27d8a
Autor:
Susana Lechuga, Armando Marino-Melendez, Nayden G. Naydenov, Atif Zafar, Manuel B. Braga-Neto, Andrei I. Ivanov
Publikováno v:
Cells, Vol 13, Iss 5, p 370 (2024)
The integrity and permeability of epithelial and endothelial barriers depend on the formation of tight junctions, adherens junctions, and a junction-associated cytoskeleton. The establishment of this junction–cytoskeletal module relies on the corre
Externí odkaz:
https://doaj.org/article/3e32373652c245ccb6368af6eac54f93
Autor:
Maria S. Shutova, Julia Borowczyk, Barbara Russo, Sihem Sellami, Justyna Drukala, Michal Wolnicki, Nicolo C. Brembilla, Gurkan Kaya, Andrei I. Ivanov, Wolf-Henning Boehncke
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106195- (2023)
Summary: Aberrant mechanotransduction and compromised epithelial barrier function are associated with numerous human pathologies including inflammatory skin disorders. However, the cytoskeletal mechanisms regulating inflammatory responses in the epid
Externí odkaz:
https://doaj.org/article/ace74f00c2814633aab0baa53cf660d7
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Disruption of the intestinal epithelial barrier is a hallmark of mucosal inflammation. It increases exposure of the immune system to luminal microbes, triggering a perpetuating inflammatory response. For several decades, the inflammatory stimuli-indu
Externí odkaz:
https://doaj.org/article/096fab9d79594fca9363ed1944d3563e