Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Andrei A. Lebedev"'
Publikováno v:
Research Results in Pharmacology, Vol 10, Iss 2, Pp 97-105 (2024)
Introduction: The aim of our study was to investigate the effects of ghrelin receptor antagonist [D-Lys-3]-GHRP-6 on impulsivity and compulsivity in a model of gambling addiction in adult rats after maternal deprivation MD in early ontogenesis. Ma
Externí odkaz:
https://doaj.org/article/49b641225ca24c83a59509e8a8b8a45e
Autor:
Petr D. Shabanov, Aleksandra A. Blazhenko, Aleksandr S. Devyashin, Platon P. Khokhlov, Andrei A. Lebedev
Publikováno v:
Research Results in Pharmacology, Vol 7, Iss 1, Pp 41-46 (2021)
The aim: of the study was to investigate the level of ghrelin in various brain structures during a stress response in Zebrafish to a predator, to evaluate this indicator as a potential biomarker of stress, and the effect of a benzodiazepine tranquili
Externí odkaz:
https://doaj.org/article/0750453b1b4941a186da114dc9907c6a
Autor:
Andrei A. Lebedev, Yulia N. Bessolova, Nikolai S. Efimov, Eugeny R. Bychkov, Andrei V. Droblenkov, Petr D. Shabanov
Publikováno v:
Research Results in Pharmacology, Vol 6, Iss 1, Pp 81-91 (2020)
Introduction: The purpose of this work was to prove that the reaction of food self-deprivation in “fed up” rats is a suitable model for studying the emotional overeating in the experiment. Methods: The self-deprivation reaction, i.e. self-isolati
Externí odkaz:
https://doaj.org/article/1b432cd28cc04092bd4a81074504866b
Autor:
Marat I. Airapetov, Sergei O. Eresko, Andrei A. Lebedev, Evgenii R. Bychkov, Petr D. Shabanov
Publikováno v:
Physiological Reports, Vol 9, Iss 21, Pp n/a-n/a (2021)
Abstract The review presents data on the expression of growth hormone secretagogue receptor 1a (GHS‐R1a) in the brain regions in model animals (zebrafish, rodents, primates), and in the human brain. Studies show widespread distribution of the recep
Externí odkaz:
https://doaj.org/article/c48f087da9ee405bb2ef0f0fe985c013
Publikováno v:
Research Results in Pharmacology, Vol 5, Iss 3, Pp 11-19 (2019)
Introduction: Studies on the mechanisms of the reinforcing action of opioid and non-opioid narcotics confirmed the existence in the brain of a specialized system named the extended amygdala. Materials and methods: To clarify the value of the extende
Externí odkaz:
https://doaj.org/article/7400877d8a994fae9c1605991c2b43b4
Autor:
Sarng S. Pyurveev, Mikhail S. Nekrasov, Nikolay S. Dedanishvili, Albina S. Nekrasova, Tatyana V. Brus, Andrei A. Lebedev, Nicanor V. Lavrov, Aleksandra V. Podrezova, Ruslan I. Glushakov, Petr D. Shabanov
Publikováno v:
Reviews on Clinical Pharmacology and Drug Therapy. 21:69-78
BACKGROUND: Exposure to acute or chronic stress contributes to the occurrence of various disorders of the central nervous system, psycho-emotional sphere, as well as increases the risks of development of various forms of addiction. AIM: The aim of th
Autor:
Andrei A. Lebedev, Valeriya V. Lukashkova, Anna G. Pshenichnaya, Eugeny R. Bychkov, Viktor A. Lebedev, Vladimir V. Rusanovsky, Petr D. Shabanov
Publikováno v:
Psychopharmacology & biological narcology. 1:69-79
BACKGROUND: Currently, no study has investigated on the role of ghrelin in the reinforcing system and emotional behavior. Previously, we examined the properties of GHSR1A antagonist [D-Lys3]-GHRP-6 to reduce negative emotional states caused by stress
Publikováno v:
Psychopharmacology & biological narcology. 1:48-62
BACKGROUND: The search for new drugs potentially effective in stopping the development of pathological addictions is an urgent task of experimental psychopharmacology. AIM: To examine the participation of brain monoaminergic systems in the mechanisms
Autor:
Maria V. Litvinova, Alexander N. Trofimov, Petr D. Shabanov, Andrei A. Lebedev, Evgeny R. Bychkov, Nikolay А. Arseniev, Alexander I. Tyukavin
Publikováno v:
Pharmacy Formulas. 4:82-96
One of the unresolved problems on the way to improving the pharmacotherapy of CNS diseases is the development and creation of technologies that allow drugs to cross the blood-brain barrier (BBB). The review discusses modern methods of drug delivery t
Autor:
Alexandra A. Blazhenko, Platon P. Khokhlov, Andrei A. Lebedev, Eugenii R. Bychkov, Sergei V. Kazakov, Petr D. Shabanov
Publikováno v:
Psychopharmacology & biological narcology. 13:37-42
BACKGROUND: Literature data indicated that ghrelin may be a stress neuropeptide in some animals, including Danio rerio. AIM: The aim of the study was to measure the levels of ghrelin in Danio rerio brain (forebrain, midbrain, and hindbrain) after pre