Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Andrei A. Gakh"'
Publikováno v:
Molecules, Vol 15, Iss 2, Pp 997-1006 (2010)
The title compounds, (4-trifluoromethoxyphenyl)-2,5-dimethyl-3-(2-R-thiazol-4-yl)-1H-pyrroles, were prepared in four steps starting from commercially available 4-trifluoromethoxyaniline. The pyrrole (second ring) was added in one step using the Paal-
Externí odkaz:
https://doaj.org/article/abde1ff8c63640809e4d2028968108e4
Publikováno v:
Molecules, Vol 11, Iss 4, Pp 219-231 (2006)
A compact Modular Chemical Descriptor Language (MCDL) chemical structure editor (Java applet) is described. The small size (approximately 200 KB) of the applet allows its use to display and edit chemical structures in various Internet applications. T
Externí odkaz:
https://doaj.org/article/62071e4ee6d144d68c50f4f910cb52b1
Autor:
Andrei A. Gakh
Publikováno v:
Mendeleev Communications. 31:297-299
Pulsed aluminum batteries were developed in the course of ongoing research in technomimetics. They can amplify external electrical trigger signals, leading to potential applications as components of electrochemical computing systems and self-powered
Autor:
Andrei A. Gakh
Comprehensive look at mechanical molecular devices that mimic the behavior of man-made devices Molecular devices and molecular machines are individual molecules and molecular systems capable of providing valuable device-like functions. Many of them h
Autor:
Andrei A, Gakh, Yuriy, Shermolovich
Publikováno v:
Current Topics in Medicinal Chemistry. 14:952-965
This review is a follow-up to the previous chapter, "Monofluorinated Heterocycles" (Topics in Heterocyclic Chemistry, 2012, 33-63), and presents an overview of synthetic chemistry of heterocycles with only one trifluoromethyl group directly attached
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:1262-1268
The combination of experimental (inhibition of colchicine binding) and computational (COMPARE, docking studies) data unequivocally identified diaryl 5-amino-1,2,4-oxadiazoles as potent tubulin inhibitors. Good correlation was observed between tubulin
Autor:
Michael N. Burnett, Andrei A. Gakh
Publikováno v:
Journal of Fluorine Chemistry. 132:88-93
Thorough examination of the current literature as well as publicly available databases allowed us to qualify aromatic fluorine as a unique modulator of biological properties of organic compounds. In some rare cases, introduction of fluorine increased
Publikováno v:
Journal of Fluorine Chemistry. 131:1044-1048
Synthesis of 3-fluoroimidazo[1,2-a]pyrimidines and 5-fluoroimidazo[2,1-b][1,3]thiazoles was accomplished via triethyl phosphite-induced heterocyclization of the corresponding N-(heteroarylimino)trifluoropyruvates. This method provides a convenient ap