Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Andrei, Kornilov"'
Autor:
Stephen D, Barrett, Melissa C, Holt, James B, Kramer, Bradlee, Germain, Chi S, Ho, Fred L, Ciske, Andrei, Kornilov, Joseph M, Colombo, Adam, Uzieblo, James P, O'Malley, Thomas A, Owen, Adam J, Stein, Maria I, Morano
Publikováno v:
Journal of medicinal chemistry. 62(9)
A series of small-molecule full agonists of the prostaglandin E
Autor:
John T. Welch, Michael Higgins, Michael H. Cynamon, Tracy Sanchez, Benjamin H. Brodsky, Woo Jin Chung, Leonid B. Heifets, Andrei Kornilov
Publikováno v:
Tuberculosis. 88:410-419
Pyrazinamide is unusual among anti-tuberculous agents in its ability to promote a durable cure and shorten the duration of therapy. Yet the basis for this effect is not well understood. A particularly effective strategy for the development of new dru
Autor:
John T. Welch, Seiichiro Higashiya, Paul J. Toscano, Silvana C. Ngo, Rolf U. Claessen, Christopher C. Wells, Andrei Kornilov, Kulbinder K Banger, Evgeny V. Dikarev
Publikováno v:
Journal of Organometallic Chemistry. 689:71-81
The sila-β-diketone, 2,2,6,6-tetramethyl-2-silaheptane-3,5-dione (tmshdH), was synthesized by the condensation of the anion of 2-trimethylsilyl-1,3-dithiane with 1-bromo-3,3-dimethylbutan-2-one, followed by unmasking of the latent carbonyl moiety wi
Publikováno v:
Journal of Fluorine Chemistry. 111:69-76
A three-stage strategy is proposed to prepare α,α-difluoro-β-amino acids starting from aldehydes and with ethyl bromodifluoroacetate as a fluorine source. The Mitsunobu reaction as a key step was studied by 31 P and 19 F NMR for alkyl- and aryl-su
Autor:
Rolf U. Claessen, Kulbinder K Banger, Alain E. Kaloyeros, Eric Eisenbraun, Andrei Kornilov, Paul J. Toscano, John T. Welch
Publikováno v:
Inorganic Chemistry Communications. 4:496-500
A facile preparation of 2,2,6,6-tetramethyl-2-sila-3,5-heptanedione (tmshdH), exemplar of a new class of ligands, the sila-β-diketones, has been developed. Silicon substitution in the ligands has profound effects on the volatility, thermal propertie
Publikováno v:
Israel Journal of Chemistry. 39:171-178
Peterson olefination of the alkyl and aryl aldehydes with C,O-bis(triethylsilyl)fluoroketene acetal 1 promoted by titanium tetrachloride and dimethylaluminum chloride was investigated. Desired fluoroolefins were formed with high stereoselectivity and
Autor:
Andrei Kornilov, Ahmed Abouabdellah, Danièle Bonnet-Delpon, Cyrille Richard, Jean-Pierre Bégué, Isabelle Rodrigues
Publikováno v:
The Journal of Organic Chemistry. 63:6529-6534
anti-(Trifluoromethyl) β-amino alcohols 2 have been prepared in good yields and with 90% diastereoisomeric excess through a reaction of 1-(trifluoromethyl) epoxy ethers 3 with dimethylaluminum amide, followed by the in situ chelation-controlled ster
Autor:
Alberto Arnone, Danièle Bonnet-Delpon, Rosanna Cardillo, G. Biagini, Giuseppe Resnati, Jean-Pierre Bégué, Andrei Kornilov
Publikováno v:
Tetrahedron Letters. 37:3903-3906
Several microorganisms have been employed in the reduction of two α,α,α-trifluoro-α′-sulfenylketones. Some of them produce corresponding alcohols in high diastero- and enantioselection, the high conversion in a single enantiomer being secured b
Publikováno v:
Synthesis. 1996:529-532
Publikováno v:
ChemInform. 27