Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Andrei, Alexsson"'
Autor:
Jonas Carlsson Almlöf, Andrei Alexsson, Juliana Imgenberg-Kreuz, Lina Sylwan, Christofer Bäcklin, Dag Leonard, Gunnel Nordmark, Karolina Tandre, Maija-Leena Eloranta, Leonid Padyukov, Christine Bengtsson, Andreas Jönsen, Solbritt Rantapää Dahlqvist, Christopher Sjöwall, Anders A. Bengtsson, Iva Gunnarsson, Elisabet Svenungsson, Lars Rönnblom, Johanna K. Sandling, Ann-Christine Syvänen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Genome-wide association studies have identified risk loci for SLE, but a large proportion of the genetic contribution to SLE still remains unexplained. To detect novel risk genes, and to predict an individual’s SLE risk we designed a rando
Externí odkaz:
https://doaj.org/article/95b05eb647a546ff93ea49bf8605180e
Autor:
Olof Berggren, Niklas Hagberg, Andrei Alexsson, Gert Weber, Lars Rönnblom, Maija-Leena Eloranta
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183946 (2017)
Hyperactive B cells and a continuous interferon (IFN)-α production by plasmacytoid dendritic cells (pDCs) play a key role in systemic lupus erythematosus (SLE). We asked whether the interaction between B cells and pDCs stimulated with RNA-containing
Externí odkaz:
https://doaj.org/article/9c656a1d448242d5a766e5906ef647ab
Autor:
Robert G. Cooper, Ingrid E. Lundberg, Simon Rothwell, Lina Hultin Rosenberg, Maryam Dastmalchi, Anna Tjärnlund, Øyvind Molberg, Jennifer R. S. Meadows, Antonella Notarnicola, Matteo Bianchi, Sergey V. Kozyrev, Helena Andersson, Lars Rönnblom, Hector Chinoy, Johanna K. Sandling, Louise C. Pyndt Raun Diederichsen, Kerstin Lindblad-Toh, Andrei Alexsson, Pascal Pucholt, Leonid Padyukov, Janine A. Lamb, Åsa Karlsson
Publikováno v:
Bianchi, M, Kozyrev, S V, Notarnicola, A, Hultin Rosenberg, L, Karlsson, Å, Pucholt, P, Rothwell, S, Alexsson, A, Sandling, J K, Andersson, H, Cooper, R G, Padyukov, L, Tjärnlund, A, Dastmalchi, M, Meadows, J R S, Pyndt Diederichsen, L, Molberg, Ø, Chinoy, H, Lamb, J, Rönnblom, L, Lindblad-Toh, K, Lundberg, I E & ImmunoArray Development Consortium 2022, ' Contribution of Rare Genetic Variation to Disease Susceptibility in a Large Scandinavian Myositis Cohort ', Arthritis & Rheumatology, vol. 74, no. 2, pp. 342-352 . https://doi.org/10.1002/art.41929
OBJECTIVE: Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of complex autoimmune conditions characterized by inflammation in skeletal muscle and extramuscular compartments, and interferon (IFN) system activation. We undertook this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a1d4271de81ae3e380011e6f6c7321
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-458674
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-458674
Autor:
Christer Sundström, Andrei Alexsson, Peter Hollander, Gunilla Enblad, Cecilia Lindskog, Claes Ladenvall, Rose-Marie Amini, Larry Mansouri, Maysaa Abdulla, Mattias Berglund, Lucia Cavelier
Background Programmed cell death 1 (PD-1) and its ligands PD-L1 and PD-L2, as well as Indoleamine 2,3-deoxygenase (IDO1) can be expressed both by tumor and microenvironmental cells and are crucial for tumor immune escape. We aimed to evaluate the rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0d748bcbf780353efab5d62304f78c
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-403484
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-403484
Autor:
Katrine Brække Norheim, Juliana Imgenberg-Kreuz, Andrei Alexsson, Svein Joar Auglænd Johnsen, Kjetil Bårdsen, Johan Gorgas Brun, Rezvan Kiani Dehkordi, Elke Theander, Thomas Mandl, Roland Jonsson, Wan-Fai Ng, Christopher J Lessard, Astrid Rasmussen, Kathy Sivilis, Lars Ronnblom, Roald Omdal
Publikováno v:
e001832
RMD Open
RMD Open
ObjectivesFatigue is common and severe in primary Sjögren’s syndrome (pSS). The aim of this study was to identify genetic determinants of fatigue in pSS through a genome-wide association study.MethodsPatients with pSS from Norway, Sweden, UK and U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f9e851a6e49b4b93a54b7985ac6563
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-462471
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-462471
Autor:
Ann-Christine Syvänen, Anne Troldborg, Christopher Sjöwall, Dag Leonard, Sarah Reid, Anne Voss, Niklas Hagberg, Elisabet Svenungsson, Anders A. Bengtsson, Andreas Jönsen, Søren Jacobsen, Lars Rönnblom, Øyvind Molberg, Pascal Pucholt, Iva Gunnarsson, Karoline Lerang, Andrei Alexsson, Johanna K. Sandling
Publikováno v:
Reid, S, Hagberg, N, Sandling, J K, Alexsson, A, Pucholt, P, Sjöwall, C, Lerang, K, Jönsen, A, Gunnarsson, I, Syvänen, A-C, Troldborg, A M, Voss, A, Bengtsson, A A, Molberg, Ø, Jacobsen, S, Svenungsson, E, Rönnblom, L & Leonard, D 2021, ' Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus ', Annals of the Rheumatic Diseases, vol. 80, no. 9, pp. 1183-1189 . https://doi.org/10.1136/annrheumdis-2020-219727
Reid, S, Hagberg, N, Sandling, J K, Alexsson, A, Pucholt, P, Sjöwall, C, Lerang, K, Jönsen, A, Gunnarsson, I, Syvänen, A C, Troldborg, A M, Voss, A, Bengtsson, A A, Molberg, Ø, Jacobsen, S, Svenungsson, E, Rönnblom, L & Leonard, D 2021, ' Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus ', Annals of the rheumatic diseases, vol. 80, no. 9, pp. 1183-1189 . https://doi.org/10.1136/annrheumdis-2020-219727
Reid, S, Hagberg, N, Sandling, J K, Alexsson, A, Pucholt, P, Sjöwall, C, Lerang, K, Jönsen, A, Gunnarsson, I, Syvänen, A C, Troldborg, A M, Voss, A, Bengtsson, A A, Molberg, Ø, Jacobsen, S, Svenungsson, E, Rönnblom, L & Leonard, D 2021, ' Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus ', Annals of the Rheumatic Diseases, vol. 80, no. 9, pp. 1183–1189 . https://doi.org/10.1136/annrheumdis-2020-219727
Annals of the Rheumatic Diseases
Reid, S, Hagberg, N, Sandling, J K, Alexsson, A, Pucholt, P, Sjöwall, C, Lerang, K, Jönsen, A, Gunnarsson, I, Syvänen, A C, Troldborg, A M, Voss, A, Bengtsson, A A, Molberg, Ø, Jacobsen, S, Svenungsson, E, Rönnblom, L & Leonard, D 2021, ' Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus ', Annals of the rheumatic diseases, vol. 80, no. 9, pp. 1183-1189 . https://doi.org/10.1136/annrheumdis-2020-219727
Reid, S, Hagberg, N, Sandling, J K, Alexsson, A, Pucholt, P, Sjöwall, C, Lerang, K, Jönsen, A, Gunnarsson, I, Syvänen, A C, Troldborg, A M, Voss, A, Bengtsson, A A, Molberg, Ø, Jacobsen, S, Svenungsson, E, Rönnblom, L & Leonard, D 2021, ' Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus ', Annals of the Rheumatic Diseases, vol. 80, no. 9, pp. 1183–1189 . https://doi.org/10.1136/annrheumdis-2020-219727
Annals of the Rheumatic Diseases
ObjectiveTo investigate how genetics influence the risk of smoking-related systemic lupus erythematosus (SLE) manifestations.MethodsPatients with SLE (ndiscovery cohort=776, nreplication cohort=836) were genotyped using the 200K Immunochip single nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ef27ed8961933399a4cb6353c326e1
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-178731
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-178731
Autor:
Søren Jacobsen, Lars Rönnblom, Johanna K. Sandling, Anne Troldborg, Iva Gunnarsson, Sarah Reid, Anne Voss, Karoline Lerang, Øyvind Molberg, Christopher Sjöwall, Andreas Jönsen, Dag Leonard, Anders A. Bengtsson, Elisabet Svenungsson, Andrei Alexsson, Ann-Christine Syvänen, Pascal Pucholt
Publikováno v:
Poster presentations.
Background Patients with SLE have increased morbidity and mortality due to cardiovascular disease. Here, we construct and validate a polygenic risk score (PRS) for myocardial infarction (MI) in SLE. Methods Patients with SLE (European decent, ≥4 AC
Autor:
Elisabet Svenungsson, Malena Loberg Haarhaus, Iva Gunnarsson, Anne Troldborg, Anne Voss, Andreas Jönsen, Gunnel Nordmark, Søren Jacobsen, Solbritt Rantapää-Dahlqvist, Lars Rönnblom, Anders A. Bengtsson, Johanna K. Sandling, Joanne Nititham, Karoline Lerang, Christopher Sjöwall, Dag Leonard, Lindsey A. Criswell, Øyvind Molberg, Karin Bolin, Andrei Alexsson, Ann-Christine Syvänen, Pascal Pucholt
Publikováno v:
Oral presentations.
Background Lupus Nephritis (LN) is a cause of significant morbidity in SLE. While the genetic background to SLE has been well characterized, less is known about genes predisposing to LN. Methods The study consisted of 2886 SLE patients, including 947
Autor:
Karin Bolin, Elisabet Svenungsson, Solbritt Rantapää-Dahlqvist, Andrei Alexsson, Martina Frodlund, Sarah Reid, Andreas Jönsen, Anders A. Bengtsson, Lars Rönnblom, Johanna K. Sandling, Iva Gunnarsson, Ann-Christine Syvänen, Maija-Leena Eloranta, Christine Bengtsson, Christopher Sjöwall, Dag Leonard
Publikováno v:
Abstracts.
Background Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease with a complex genetic etiology. Over 100 risk genes for SLE have been identified at genome-wide significance, but their overall effect on disease severity has not previou
Autor:
Iva Gunnarsson, C Sjöwal, Sarah Reid, Martina Frodlund, Solbritt Rantapää-Dahlqvist, Lars Rönnblom, Anders A. Bengtsson, Andreas Jönsen, Johanna K. Sandling, A. C. Syvanen, Andrei Alexsson, Dag Leonard, Elisabet Svenungsson, Christine Bengtsson
Publikováno v:
S4a – Longterm outcome.
Background Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease with a complex genetic aetiology. The overall effect of hereditary risk on organ damage has so far not been studied. We therefore assessed the relationship between genetic