Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Andreea Daraba"'
Autor:
Zoltán Farkas, Dorottya Kalapis, Zoltán Bódi, Béla Szamecz, Andreea Daraba, Karola Almási, Károly Kovács, Gábor Boross, Ferenc Pál, Péter Horváth, Tamás Balassa, Csaba Molnár, Aladár Pettkó-Szandtner, Éva Klement, Edit Rutkai, Attila Szvetnik, Balázs Papp, Csaba Pál
Publikováno v:
eLife, Vol 7 (2018)
Proteins are necessary for cellular growth. Concurrently, however, protein production has high energetic demands associated with transcription and translation. Here, we propose that activity of molecular chaperones shape protein burden, that is the f
Externí odkaz:
https://doaj.org/article/6f8039d030b34e66ac201c61828ad227
Autor:
Miklos Halmai, Orsolya Frittmann, Zoltan Szabo, Andreea Daraba, Vamsi K Gali, Eva Balint, Ildiko Unk
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161307 (2016)
Proliferating cell nuclear antigen (PCNA) plays a key role in many cellular processes and due to that it interacts with a plethora of proteins. The main interacting surfaces of Saccharomyces cerevisiae PCNA have been mapped to the interdomain connect
Externí odkaz:
https://doaj.org/article/38b945b6a0b74c078930662eaf0c279d
Autor:
Dorottya Kalapis, Ana R Bezerra, Zoltán Farkas, Peter Horvath, Zoltán Bódi, Andreea Daraba, Béla Szamecz, Ivo Gut, Mónica Bayes, Manuel A S Santos, Csaba Pál
Publikováno v:
PLoS Biology, Vol 13, Iss 11, p e1002291 (2015)
Translational errors occur at high rates, and they influence organism viability and the onset of genetic diseases. To investigate how organisms mitigate the deleterious effects of protein synthesis errors during evolution, a mutant yeast strain was e
Externí odkaz:
https://doaj.org/article/a233480ffc9f4770aea9f2fdf57f35a0
Autor:
Ildiko Unk, Andreea Daraba
Publikováno v:
Bio-Protocol, Vol 4, Iss 20 (2014)
There are several methods to measure the capacity of yeast cell to respond to environmental impacts on their genome by mutating it. One frequently used method involves the detection of forward mutations in the CAN1 gene. The CAN1 gene encodes for an
Externí odkaz:
https://doaj.org/article/56259e665a6e4b9eaac25f5e0842e169
Autor:
Ildiko Unk, Andreea Daraba
Publikováno v:
Bio-Protocol, Vol 4, Iss 20 (2014)
The baker’s yeast, Saccharomyces cerevisiae is a widely used model organism in molecular biology because of the high homology it shares with human cells in many basic cellular processes such as DNA replication, repair, recombination, transcription,
Externí odkaz:
https://doaj.org/article/ff59de42ab0a41359bdab2fbd02a31f5
Publikováno v:
PLoS Biology, Vol 12, Iss 1, p e1001771 (2014)
DNA damages hinder the advance of replication forks because of the inability of the replicative polymerases to synthesize across most DNA lesions. Because stalled replication forks are prone to undergo DNA breakage and recombination that can lead to
Externí odkaz:
https://doaj.org/article/d641bd02ec82485cb7d6de746fce31c2
Autor:
Dorottya Kalapis, Patrick Kemmeren, Karola Almási, Juan F. Poyatos, Csaba Pál, Richard A. Notebaart, Balázs Papp, Zoltán Bódi, Bálint Kintses, Zoltán Farkas, Djordje Bajić, Andreea Daraba, Frank C. P. Holstege, Károly Kovács
Publikováno v:
Molecular Biology and Evolution
Molecular Biology and Evolution, 38(3), 1137-1150
Molecular Biology and Evolution 38 (2020) 3
Molecular Biology and Evolution, 38(3), 1137-1150
Molecular Biology and Evolution 38 (2020) 3
The fitness impact of loss-of-function mutations is generally assumed to reflect the loss of specific molecular functions associated with the perturbed gene. Here, we propose that rewiring of the transcriptome upon deleterious gene inactivation is fr
Autor:
Zoltán Farkas, Dorottya Kalapis, Zoltán Bódi, Béla Szamecz, Andreea Daraba, Karola Almási, Károly Kovács, Gábor Boross, Ferenc Pál, Péter Horváth, Tamás Balassa, Csaba Molnár, Aladár Pettkó-Szandtner, Éva Klement, Edit Rutkai, Attila Szvetnik, Balázs Papp, Csaba Pál
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f21644422f00f8c218c67bd561df8d5
https://doi.org/10.7554/elife.29845.024
https://doi.org/10.7554/elife.29845.024
Autor:
Csaba Pál, Peter Horvath, Zoltán Farkas, Manuel A. S. Santos, Ivo Gut, Ana R. Bezerra, Dorottya Kalapis, Zoltán Bódi, Andreea Daraba, Mònica Bayés, Bé la Szamecz
Publikováno v:
PLoS Biology, Vol 13, Iss 11, p e1002291 (2015)
research@ua; Vol 6 (2015); 39
research@ua; vol. 6 (2015); 39
PLoS Biology
PLOS Biology
research@ua; Vol 6 (2015); 39
research@ua; vol. 6 (2015); 39
PLoS Biology
PLOS Biology
Translational errors occur at high rates, and they influence organism viability and the onset of genetic diseases. To investigate how organisms mitigate the deleterious effects of protein synthesis errors during evolution, a mutant yeast strain was e