Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andreas Wolfram, Henkel"'
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 13 (2019)
Frontiers in Neuroscience, Vol 13 (2019)
There is a general consensus that synaptic vesicular release by a full collapse process is the primary machinery of synaptic transmission. However, competing view suggests that synaptic vesicular release operates via a kiss-and-run mechanism. By moni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd285b7ae3e223b45d5d5ad1dfbb0fd
https://opus4.kobv.de/opus4-fau/files/12891/fnins-13-01047-g006.tif
https://opus4.kobv.de/opus4-fau/files/12891/fnins-13-01047-g006.tif
Publikováno v:
Frontiers in Neuroinformatics
Frontiers in Neuroinformatics, Vol 13 (2019)
Frontiers in Neuroinformatics, Vol 13 (2019)
Mobility quantification of single cells and cellular processes in dense cultures is a challenge, because single cell tracking is impossible. We developed a software for cell structure segmentation and implemented 2 algorithms to measure motility spee
Publikováno v:
Neuroscience. 280:318-327
The "plasticity hypothesis" proposes that major depression is caused by morphological and biochemical modifications in neurons and astrocytes and those beneficial pharmacological effects of selective-serotonin-reuptake-inhibitors (SSRI) are at least
Autor:
Carsten H. Tischbirek, Jasmin Jung, Teja W. Groemer, Armin Stroebel, Oliver Welzel, Andreas Wolfram Henkel, Silvio O. Rizzoli, Johannes Kornhuber, Katrin Ebert
Publikováno v:
Biophysical Journal. 100(3):593-601
Hippocampal neurons in tissue culture develop functional synapses that exhibit considerable variation in synaptic vesicle content (20–350 vesicles). We examined absolute and fractional parameters of synaptic vesicle exocytosis of individual synapse
Autor:
Julia C. Fuerst, Johannes Kornhuber, Armin Stroebel, Dominikus Bönsch, Oliver Welzel, Andreas Wolfram Henkel, Teja W. Groemer
Publikováno v:
Journal of Cellular Physiology. 226:362-368
Spastin is a microtubule severing ATPase that regulates intracellular and axonal transport of vesicles. Intracellular vesicle trafficking was analyzed in differentiated SH-SY5Y-neuroblastoma cells, transfected with spastin wild-type and three spastin
Autor:
Andreas Wolfram Henkel
Publikováno v:
Biophysical Journal. 108(2)
Neural transmission and information processing requires not only quantitative modulation of transmitter release but also temporal coordination of the information flow. Here we describe that the onset of synaptic exocytosis in specialized individual s
Publikováno v:
Biophysical Journal. 112:434a
The “plasticity hypothesis” proposes that major depression is caused by morphological and biochemical modifications in neurons and astrocytes and that the illness is at least partially associated with modifications of cellular communications betw
Autor:
Katharina Müller, Thorsten Müller, Johannes Kornhuber, Katrin Marcus, Andreas Wolfram Henkel, Piotr Lewczuk, Jens Wiltfang
Neurochemical differential diagnosis between Alzheimer's disease and other dementias is currently based on CSF biomarkers. Here, we report a method by which potential biomarkers can be identified in blood. Blood plasma samples from seven well-charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a21d76dbcbb3425ce682835a7025e61
https://www.ncbi.nlm.nih.gov/pubmed/22415063
https://www.ncbi.nlm.nih.gov/pubmed/22415063
Autor:
Sabine Ott, Maria Kerstin Henkel, Andreas Wolfram Henkel, Zoran B. Redzic, Jens Wiltfang, Johannes Kornhuber
Publikováno v:
Molecular and cellular biochemistry. 349(1-2)
Neuritic amyloid plaques and neurofibrillary tangles, consisting of hyperphosphorylated tau protein, are the hallmarks of Alzheimer disease. It is not clear so far, how both structures are functionally and physiologically connected. We have investiga
Autor:
Andreas Wolfram, Henkel, Oliver, Welzel, Teja Wolfgang, Groemer, Philipp, Tripal, Andrea, Rotter, Johannes, Kornhuber
Publikováno v:
Journal of neurochemistry. 114(3)
Effects of the antidepressant fluoxetine on stimulation-dependent synaptic vesicle exocytosis were examined in cultured primary hippocampal neurons. Synaptic vesicles were fluorescently labeled in vitro with FM1-43, washed and subsequently destained