Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Andreas W. Stuke"'
Autor:
Lars Heinig, Daniel A. Mueller, Andreas W. Stuke, Arne Wrede, Reiner Schulte, Astrid Krueger, Sanja Ramljak
Publikováno v:
Hybridoma. 29:463-472
Because of their high antigen specificity and metabolic stability, genetically engineered human monoclonal antibodies are on the way to becoming one of the most promising medical diagnostics and therapeutics. In order to establish an in vitro system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c3b51445a2d10f19570c21c5e92f3d
https://doi.org/10.1089/hyb.2010.0041
https://doi.org/10.1089/hyb.2010.0041
Publikováno v:
Protein Expression and Purification. 70:129-136
In transmissible spongiform encephalopathy (TSE) pathogenesis the cellular prion protein (PrP(C)) is converted into its pathogenic PrP(Sc) isoform. Prion protein gene (Prnp) deficient mice (PrP(0/0)) are resistant to PrP(Sc) infection, but following
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5badcb1127d00ee238e196be0e8551df
https://doi.org/10.1016/j.pep.2009.09.015
https://doi.org/10.1016/j.pep.2009.09.015
Autor:
Gerhard Hunsmann, Uwe Hahmann, Barbara Yutzy, Andreas W. Stuke, Johannes Löwer, Andreas Hoffmann, Mechthild Törner, Edgar Holznagel, Kay-Martin Hanschman, Cheick Coulibaly, Walter J. Schulz-Schaeffer
Publikováno v:
Transfusion. 50:452-466
BACKGROUND: The cellular prion protein (PrPc) plays a central role in prion diseases such as variant Creutzfeldt-Jakob disease. This disease can be transmitted by blood transfusion. However, the exact kinetics of blood infectivity and the blood fract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a13dd7c86e4b3ed923466fff8288c2b
https://doi.org/10.1111/j.1537-2995.2009.02437.x
https://doi.org/10.1111/j.1537-2995.2009.02437.x
Autor:
David J. Picketts, Fraser W. Scott, Rudolph Reimer, Andreas W. Stuke, Gen-Sheng Wang, Alexander Strom
Publikováno v:
European journal of cell biology. 90(5)
Several physiological processes have been purported for cellular prion protein (PrP(C)). However, the physiological function of PrP(C) is still unclear and the cellular localization of PrP(C) remains a subject of debate. PrP(C) is expressed in a wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ade0a792702a4358db5f7cb6baecaa
https://pubmed.ncbi.nlm.nih.gov/21277044
https://pubmed.ncbi.nlm.nih.gov/21277044
Autor:
Marianna Farsang, Andreas W. Stuke, Tibor Kovács, Imre Szirmai, Zsuzsanna Arányi, Gabor G. Kovacs
Publikováno v:
Alzheimer's & Dementia. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d3d17129e1943ca368c0a2a07961ea4
https://doi.org/10.1016/j.jalz.2009.04.621
https://doi.org/10.1016/j.jalz.2009.04.621
Publikováno v:
AIDS. 4:847-858
The complete nucleotide sequence of an HIV-2 isolate derived from a German AIDS patient with predominantly neurological symptoms is reported. The HIV-2BEN sequence is highly divergent from those of previously described HIV-2 and SIV strains. Evolutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f2e1cc91879648e8673a58801198bc
https://doi.org/10.1097/00002030-199009000-00003
https://doi.org/10.1097/00002030-199009000-00003
Autor:
Uwe Hahmann, Barbara Yutzy, Andreas W. Stuke, Cheick Coulibaly, Edgar Holznagel, Johannes Löwer, Gerhard Hunsmann, Jean-Philippe Deslys
Publikováno v:
The Journal of general virology. 88(Pt 12)
Experimental transmission of bovine spongiform encephalopathy (BSE) to cynomolgus monkeys (Macaca fascicularis) is an animal model for variant Creutzfeldt–Jakob disease (vCJD). The presence of 14-3-3 proteins in cerebrospinal fluid (CSF) samples in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf7bb43ddb16ad1e171652278ffb400
https://pubmed.ncbi.nlm.nih.gov/18024918
https://pubmed.ncbi.nlm.nih.gov/18024918
Autor:
Zsuzsanna Arányi, Andreas W. Stuke, John Collinge, Anita Csillik, Tibor Kovács, Marianna Farsang, Peter L. Lantos, Imre Szirmai, John Beck, Mátyás I. Papp
Publikováno v:
Journal of neurology, neurosurgery, and psychiatry. 78(3)
About 15% of human prion diseases are inherited, and are associated with point or insertional mutations of the prion protein gene (PRNP). Four families with six octapeptide repeat insertions (OPRI) in the PRNP gene have been described in the literatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e129350f3a8aa36bddb4ffaebe3bc97
https://pubmed.ncbi.nlm.nih.gov/17308293
https://pubmed.ncbi.nlm.nih.gov/17308293
Publikováno v:
Proteomics. 6(1)
The cellular prion protein (PrP(C)), a highly conserved glycoprotein predominantly expressed by neuronal cells, can convert into an abnormal isoform (PrP(Sc)) and provoke a transmissible spongiform encephalopathy. In spite of many studies, the physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ffc2c75d99c55c85a6169f4ddd3135
https://pubmed.ncbi.nlm.nih.gov/16294306
https://pubmed.ncbi.nlm.nih.gov/16294306
The conformational conversion of the normal cellular prion protein (PrPC) into the pathology-associated PrPSc isoform is a key event in TSEs (transmissible spongiform encephalopathies). The host PrPC molecule contains two N-linked glycosylation sites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6bf8441e68e83524b28472cea6cf98
https://europepmc.org/articles/PMC1186727/
https://europepmc.org/articles/PMC1186727/
