Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Andreas Tsouris"'
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 4, Pp 362-373 (2024)
Abstract Unraveling the genetic sources of gene expression variation is essential to better understand the origins of phenotypic diversity in natural populations. Genome-wide association studies identified thousands of variants involved in gene expre
Externí odkaz:
https://doaj.org/article/8a111588ffe7413683c2d11289da40b8
Autor:
Andreas Tsouris, Téo Fournier, Anne Friedrich, Jing Hou, Maitreya J Dunham, Joseph Schacherer
Publikováno v:
PLoS Genetics, Vol 20, Iss 1, p e1011119 (2024)
Assessing the complexity and expressivity of traits at the species level is an essential first step to better dissect the genotype-phenotype relationship. As trait complexity behaves dynamically, the classic dichotomy between monogenic and complex tr
Externí odkaz:
https://doaj.org/article/1552058c91234aa8a2f3ede0be85c7ae
Publikováno v:
Cell Genomics, Vol 4, Iss 1, Pp 100459- (2024)
Summary: Gene expression variation, an essential step between genotype and phenotype, is collectively controlled by local (cis) and distant (trans) regulatory changes. Nevertheless, how these regulatory elements differentially influence gene expressi
Externí odkaz:
https://doaj.org/article/fb4aa3db49754b8e9883b571bcfa2ebc
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract While genome sequencing and assembly are now routine, we do not have a full, precise picture of polyploid genomes. No existing polyploid phasing method provides accurate and contiguous haplotype predictions. We developed nPhase, a ploidy agn
Externí odkaz:
https://doaj.org/article/7af772ca27eb4665b8c30bce5f0d8b8d
Autor:
Anne Friedrich, Jean-Sébastien Gounot, Andreas Tsouris, Claudine Bleykasten, Kelle Freel, Claudia Caradec, Joseph Schacherer
Publikováno v:
Genome Biology and Evolution. 15
The process of domestication has variable consequences on genome evolution leading to different phenotypic signatures. Access to the complete genome sequences of a large number of individuals makes it possible to explore the different facets of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7034a05acbdacd1d1590fbf006080037
https://doi.org/10.1093/gbe/evad004
https://doi.org/10.1093/gbe/evad004
Autor:
Anne Friedrich, Jean-Sébastien Gounot, Andreas Tsouris, Claudine Bleykasten, Kelle Freel, Claudia Caradec, Joseph Schacherer
The process of domestication has variable consequences on genome evolution leading to different phenotypic signatures. Access to the complete genome sequences of a large number of individuals makes it possible to explore the different facets of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a36a36d6bc07a03bade60fbdfe831c1a
https://doi.org/10.1101/2022.09.02.506316
https://doi.org/10.1101/2022.09.02.506316
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2477
After its discovery RNA interference (RNAi) has become a powerful tool to study gene functions in different organisms. RNAi has been applied at genome-wide scale and can be nowadays performed using high-throughput automated systems (robotics). The si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c58f1b80a5484f91a8d5f2e97236a749
https://pubmed.ncbi.nlm.nih.gov/35524125
https://pubmed.ncbi.nlm.nih.gov/35524125
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622568
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aa8d1cf89b60ef7526280797d54e479
https://doi.org/10.1007/978-1-0716-2257-5_18
https://doi.org/10.1007/978-1-0716-2257-5_18
How natural variation affects phenotype is difficult to determine given our incomplete ability to deduce the functional impact of the polymorphisms detected in a population. Although current computational and experimental tools can predict and measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ec52bbc10bb1284b75fb6cf551a1ee4
https://doi.org/10.1101/2021.02.26.433108
https://doi.org/10.1101/2021.02.26.433108
Autor:
Omar Abou Saada, Andreas Tsouris, Chris Large, Anne Friedrich, Maitreya J. Dunham, Joseph Schacherer
Publikováno v:
Current Biology. 32:1350-1361.e3
Yeasts, and in particular Saccharomyces cerevisiae, have been used for brewing beer for thousands of years. Population genomic surveys highlighted that beer yeasts are polyphyletic, with the emergence of different domesticated subpopulations characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c410c01a60128b5057d09982233e9984
https://doi.org/10.1016/j.cub.2022.01.068
https://doi.org/10.1016/j.cub.2022.01.068