Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andreas Tomac"'
Publikováno v:
European Journal of Neuroscience. 12:3944-3952
Neurturin (NRTN), signalling via the GDNF family receptor alpha2 (GFRalpha2) and Ret tyrosine kinase, has recently been identified as an essential target-derived factor for many parasympathetic neurons. NRTN is expressed in salivary and lacrimal glan
Autor:
Thomas Perlmann, Eva Lindqvist, Andreas Tomac, A Mata de Urquiza, Lars Olson, Ulf Eriksson, Rolf Zetterström
Publikováno v:
European Journal of Neuroscience. 11:407-416
Retinoic acid (RA), a retinoid metabolite, acts as a gene regulator via ligand-activated transcription factors, known as retinoic acid receptors (RARs) and retinoid X receptors (RXRs), both existing in three different subtypes, alpha, beta and gamma.
Publikováno v:
European Journal of Neuroscience. 10:1508-1517
We report here the identification of a gene, termed GFRalpha-3 (glial cell line-derived neurotrophic factor family receptor alpha-3), related to GFRalpha-1 and GFRalpha-2 (also known as GDNFR-alpha and GDNFR-beta), and describe distribution of GDNFal
Autor:
Andreas Tomac, Johan Widenfalk, Christopher A. Nosrat, Barry J. Hoffer, Heiner Westphal, Lars Olson
Publikováno v:
The Journal of Neuroscience. 17:8506-8519
Cloning strategies were used to identify a gene termed glial cell line-derived neurotrophic factor receptor-beta (GDNFR-beta) related to GDNFR-alpha. In situ hybridization was then used to map cellular expression of the GDNF-related trophic factor ne
Publikováno v:
Experimental Brain Research. 115:410-422
Glial cell line-derived neurotrophic factor (GDNF) has recently been shown to signal by binding to GDNF receptor-alpha (GDNFR-alpha), after which the GDNF-GDNFR-alpha associates with and activates the tyrosine kinase receptor Ret. We have localized R
Publikováno v:
Experimental Neurology. 142:351-360
Members of the TGF-beta superfamily signal through a dual receptor system consisting of a type II receptor protein kinase that binds the ligand, after which this complex associates with a type I receptor to mediate intracellular signaling. In mammals
Autor:
Sven Lindskog, Lars Olson, Eva Lindqvist, Ted Ebendal, Barry J. Hoffer, Ingrid Strömberg, Andreas Tomac, Christopher A. Nosrat, C. Humpel
Publikováno v:
Cell and Tissue Research. 286:191-207
Glial-cell-line-derived neurotrophic factor (GDNF) is a distant member of the transforming growth factor-beta family and has potent neurotrophic effects on several classes of neurons including dopamine neurons and motoneurons. Here, we have used in s
Publikováno v:
Journal of Neuroscience Research. 40:276-284
Human recombinant glial cell line-derived neurotrophic factor (GDNF) was tested for its ability to stimulate fiber formation and neuron survival in primary cultures of peripheral ganglia dissected from the chicken embryo. GDNF, first characterized by
Publikováno v:
Nature. 373:335-339
GLIAL-CELL-LINE-DERIVED neurotrophic factor (GDNF), a recently cloned new member of the transforming growth factor-β superfamily, promotes survival of cultured fetal mesencephalic dopamine neurons1 and is expressed in the developing striatum2,3. The
Publikováno v:
Molecular Brain Research. 26:325-330
Glial cell-line derived neurotrophic factor (GDNF) has recently been cloned and shown to have trophic effects on dopaminergic nigral neurons. However, GDNF mRNA has not been detected in striatum or other forebrain areas of adult rat. Using limbic mot