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Publikováno v:
Autophagy
Previously, macroautophagy/autophagy was demonstrated to be regulated inter alia by the primary cilium. Mutations in RPGRIP1L cause ciliary dysfunctions resulting in severe human diseases summarized as ciliopathies. Recently, we showed that RPGRIP1L
Autor:
Tristan Leu, Antonia Wiegering, Andreas Struchtrup, Sophie Saunier, André Spychala, Stefanie Dahmen, Stefanie Kuschel, Christoph Gerhardt, Flora Legendre, Ulrich Rüther, Renate Dildrop, Thomas Zobel, Lisa Kalfhues, Sylvie Schneider-Maunoury, Johanna Maria Lier, Christine Vesque
Publikováno v:
The EMBO Journal
EMBO Journal
EMBO Journal, 2018, 37 (10), ⟨10.15252/embj.201797791⟩
EMBO Journal
EMBO Journal, 2018, 37 (10), ⟨10.15252/embj.201797791⟩
International audience; Ciliopathies are life-threatening human diseases caused by defective cilia. They can often be traced back to mutations of genes encoding transition zone (TZ) proteins demonstrating that the understanding of TZ organisation is