Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Andreas Stengl"'
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 4, p 79 (2023)
Externí odkaz:
https://doaj.org/article/5ccd3ffa8d0942149fea0b8ee6638a98
Autor:
Weihua Qin, Andreas Stengl, Enes Ugur, Susanne Leidescher, Joel Ryan, M. Cristina Cardoso, Heinrich Leonhardt
Publikováno v:
Nucleus, Vol 12, Iss 1, Pp 44-57 (2021)
Liquid-liquid phase separation (LLPS) mediated formation of membraneless organelles has been proposed to coordinate biological processes in space and time. Previously, the formation of phase-separated droplets was described as a unique property of HP
Externí odkaz:
https://doaj.org/article/b33c9be4f56c4da19ba98e65b7662223
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 8, p 240 (2022)
Antibody drug conjugates (ADCs) are rapidly becoming a cornerstone in targeted therapies, especially for the treatment of cancer. Currently, there are 12 FDA-approved ADCs, eight of which have been approved within the last five years, with numerous c
Externí odkaz:
https://doaj.org/article/8be6e8ff98804a54a2ee8f1a9ff0335a
Autor:
Markus Schneider, Carina Trummer, Andreas Stengl, Peng Zhang, Aleksandra Szwagierczak, M Cristina Cardoso, Heinrich Leonhardt, Christina Bauer, Iris Antes
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229144 (2020)
The multi-domain protein UHRF1 is essential for DNA methylation maintenance and binds DNA via a base-flipping mechanism with a preference for hemi-methylated CpG sites. We investigated its binding to hemi- and symmetrically modified DNA containing ei
Externí odkaz:
https://doaj.org/article/d29f8fecd7c842fc8056379ded4f8f18
Autor:
Jonathan Schwach, Andreas Stengl
Publikováno v:
BIOspektrum. 28:612-614
Antibody conjugates are a prime example of Aristotle’s famous quote: “The whole is more than the sum of its parts”. Connecting the antibody’s high binding specificity with molecules such as toxins, dyes and nucleic acids opens the doors wide
Autor:
Maike Roas, Binje Vick, Marc-André Kasper, Marina Able, Harald Polzer, Marcus Gerlach, Elisabeth Kremmer, Judith S. Hecker, Saskia Schmitt, Andreas Stengl, Verena Waller, Natascha Hohmann, Moreno Festini, Alexander Ludwig, Lisa Rohrbacher, Tobias Herold, Marion Subklewe, Katharina S. Götze, Christian P. R. Hackenberger, Dominik Schumacher, Jonas Helma-Smets, Irmela Jeremias, Heinrich Leonhardt, Karsten Spiekermann
Publikováno v:
Blood 141, 1023-1035 (2023)
Fms-like tyrosine kinase 3 (FLT3) is often overexpressed or constitutively activated by internal tandem duplication (ITD) and tyrosine kinase domain (TKD) mutations in acute myeloid leukemia (AML). Despite the use of receptor tyrosine kinase inhibito
Autor:
Andreas Stengl, Susanne Leidescher, Heinrich Leonhardt, Enes Ugur, M. Cristina Cardoso, Joel Ryan, Weihua Qin
Publikováno v:
Nucleus, Vol 12, Iss 1, Pp 44-57 (2021)
Nucleus
article-version (VoR) Version of Record
The Nucleus
Nucleus
article-version (VoR) Version of Record
The Nucleus
Liquid-liquid phase separation (LLPS) mediated formation of membraneless organelles has been proposed to coordinate biological processes in space and time. Previously, the formation of phase-separated droplets was described as a unique property of HP
Autor:
Ksenia Kolobynina, Christian P. R. Hackenberger, Heinrich Leonhardt, Jonathan Schwach, Katharina Brandstetter, Hartmann Harz, Philipp Ochtrop, M. Cristina Cardoso, Marcus Gerlach, Andreas Stengl, Jonas Helma
Publikováno v:
Chembiochem
Antibody conjugates have taken a great leap forward as tools in basic and applied molecular life sciences that was enabled by the development of chemoselective reactions for the site‐specific modification of proteins. Antibody‐oligonucleotide con
Publikováno v:
Frontiers in bioscience (Landmark edition). 27(8)
Antibody drug conjugates (ADCs) are rapidly becoming a cornerstone in targeted therapies, especially for the treatment of cancer. Currently, there are 12 FDA-approved ADCs, eight of which have been approved within the last five years, with numerous c
Autor:
Marc‐André Kasper, Andreas Stengl, Philipp Ochtrop, Marcus Gerlach, Tina Stoschek, Dominik Schumacher, Jonas Helma, Martin Penkert, Eberhard Krause, Heinrich Leonhardt, Christian P. R. Hackenberger
Publikováno v:
Angewandte Chemie. 131:11757-11762