Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Andreas Schulte-Mecklenbeck"'
Autor:
Christine Dambietz, Michael Heming, Tobias J. Brix, Andreas Schulte-Mecklenbeck, Phil-Robin Tepasse, Catharina C. Gross, Jonel Trebicka, Heinz Wiendl, Gerd Meyer zu Hörste
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Cryptococcal meningitis (CM) is a severe fungal disease in immunocompromised patients affecting the central nervous system (CNS). Host response and immunological alterations in the cerebrospinal fluid (CSF) after invasion of Cryptococcus neo
Externí odkaz:
https://doaj.org/article/33ec184b3ce34f3fa8e275347fc6142b
Autor:
Valerie E. Teschner, Ann-Katrin Fleck, Carolin Walter, Anna-Sophie Schwarze, Melanie Eschborn, Timo Wirth, Olga V. Steinberg, Andreas Schulte-Mecklenbeck, I-Na Lu, Marisol Herrera-Rivero, Claudia Janoschka, Jan D. Lünemann, Nicholas Schwab, Gerd Meyer zu Hörste, Julian Varghese, Catharina C. Gross, Refik Pul, Christoph Kleinschnitz, Simone Mader, Edgar Meinl, Monika Stoll, Heinz Wiendl, Luisa Klotz
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
Background: Cladribine is a highly effective immunotherapy that is applied in two short-term courses over 2 years and reduces relapse rate and disease progression in patients with relapsing multiple sclerosis (MS). Despite the short treatment period,
Externí odkaz:
https://doaj.org/article/620f3b4ae03d47ceb2b1381faa850bb4
Autor:
Michael Heming, Louisa Müller-Miny, Leoni Rolfes, Andreas Schulte-Mecklenbeck, Tobias J. Brix, Julian Varghese, Marc Pawlitzki, Hermann Pavenstädt, Martin A. Kriegel, Catharina C. Gross, Heinz Wiendl, Gerd Meyer zu Hörste
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract Objective Neurological manifestations of autoimmune connective tissue diseases (CTD) are poorly understood and difficult to diagnose. We here aimed to address this shortcoming by studying immune cell compositions in CTD patients with and wit
Externí odkaz:
https://doaj.org/article/ed31f4887b4b4ee18feb50acec2e2aba
Autor:
Louisa Müller-Miny, Raoul Sauer, Andreas Schulte-Mecklenbeck, Catharina C. Gross, Stjepana Kovac, Matthias Schilling, Carolin Beuker, Heinz Wiendl, Gerd Meyer zu Hörste
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
Autoantibodies against contactin-associated protein 2 (CASPR2) are usually associated with autoimmune encephalitis and neuromyotonia. Their association with inflammatory neuropathies has been described in case reports albeit all with distal symmetric
Externí odkaz:
https://doaj.org/article/67d22573ef5f4d45a4205efa98b0d812
Autor:
Michael Heming, Svea Haessner, Jolien Wolbert, I-Na Lu, Xiaolin Li, Benjamin Brokinkel, Michael Müther, Markus Holling, Walter Stummer, Christian Thomas, Andreas Schulte-Mecklenbeck, Flavia de Faria, Marlon Stoeckius, Stephan Hailfinger, Georg Lenz, Kornelius Kerl, Heinz Wiendl, Gerd Meyer zu Hörste, Oliver M. Grauer
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Background Primary central nervous system lymphoma (PCNSL) is a rare lymphoma of the central nervous system, usually of diffuse large B cell phenotype. Stereotactic biopsy followed by histopathology is the diagnostic standard. However, limit
Externí odkaz:
https://doaj.org/article/f469e31eaaf1475f9487cd81a7d88824
Autor:
Steffen Pfeuffer, Leoni Rolfes, Timo Wirth, Falk Steffen, Marc Pawlitzki, Andreas Schulte-Mecklenbeck, Catharina C. Gross, Marcus Brand, Stefan Bittner, Tobias Ruck, Luisa Klotz, Heinz Wiendl, Sven G. Meuth
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-18 (2022)
Abstract Objective Intravenous methylprednisolone is the standard treatment for a multiple sclerosis relapse; however, this fails to improve symptoms in up to one quarter of patients. Immunoadsorption is an accepted treatment for refractory relapses,
Externí odkaz:
https://doaj.org/article/0a0e3ada0a514fe3a64b5d0f52371427
Autor:
Susan Trümpelmann, Andreas Schulte‐Mecklenbeck, Olga V. Steinberg, Timo Wirth, Manfred Fobker, Lisa Lohmann, Jan D. Lünemann, Heinz Wiendl, Catharina C. Gross, Luisa Klotz
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 7, Pp 1606-1612 (2022)
Abstract The impact of distinct disease‐modifying therapies (DMTs) on severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) vaccination efficacy in patients with multiple sclerosis (MS) is still enigmatic. In this prospective comparati
Externí odkaz:
https://doaj.org/article/f05537ce2aae4b02889d23972f4c5898
Autor:
Cüneyt Sönmez, Johannes Wölfer, Markus Holling, Benjamin Brokinkel, Walter Stummer, Heinz Wiendl, Christian Thomas, Andreas Schulte-Mecklenbeck, Oliver M. Grauer
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Killer cell immunoglobulin-like receptors (KIRs) comprise a group of highly polymorphic inhibitory receptors which are specific for classical HLA class-I molecules. Peripheral blood and freshly prepared tumor cell suspensions (n = 60) as wel
Externí odkaz:
https://doaj.org/article/6859b3b672a441f1a75698cd10fa7570
Autor:
Andre Dik, Guido Widman, Andreas Schulte‐Mecklenbeck, Juri‐Alexander Witt, Julika Pitsch, Kristin S. Golombeck, Jan Wagner, Marco Gallus, Christine Strippel, Niels Hansen, Constanze Mönig, Saskia Räuber, Heinz Wiendl, Christian E. Elger, Rainer Surges, Sven G. Meuth, Christoph Helmstaedter, Catharina C. Gross, Albert J. Becker, Nico Melzer
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 12, Pp 2289-2301 (2021)
Abstract Objective Direct pathogenic effects of autoantibodies to the 65 kDa isoform of glutamic acid decarboxylase (GAD65) in autoimmune limbic encephalitis (LE) have been questioned due to its intracellular localization. We therefore hypothesized a
Externí odkaz:
https://doaj.org/article/9d05e3b0b880426b8a6d71870f8730c4
Autor:
Jonathan Repple, Svea Haessner, Andreas Johnen, Nils C. Landmeyer, Andreas Schulte-Mecklenbeck, Marc Pawlitzki, Heinz Wiendl, Gerd Meyer zu Hörste
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-6 (2021)
Abstract Background The mu-opioid agonist methadone is administered orally and used in opioid detoxification and in the treatment of moderate-to-severe pain. Acute oral methadone–use and –abuse have been associated with inflammatory and toxic cen
Externí odkaz:
https://doaj.org/article/b7beb7ca41314ec481450cd510efb910