Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andreas Schiwy"'
Autor:
Inska S. Reichstein, Alischa H. Becker, Sarah Johann, Thomas Braunbeck, Sabrina Schiwy, Henner Hollert, Andreas Schiwy
Publikováno v:
Environmental Sciences Europe, Vol 36, Iss 1, Pp 1-15 (2024)
Abstract Background The fish embryo acute toxicity (FET) test with the zebrafish (Danio rerio) was developed to assess the acute fish toxicity of chemicals or environmental samples as a replacement for the Acute Fish Test (AFT) with juvenile fish. Ho
Externí odkaz:
https://doaj.org/article/9099d166847b4452b17fe235ce3ac544
Autor:
Inska S. Reichstein, Maria König, Niklas Wojtysiak, Beate I. Escher, Luise Henneberger, Peter Behnisch, Harrie Besselink, Beat Thalmann, Julien Colas, Sarah Hörchner, Henner Hollert, Andreas Schiwy
The evaluation of single substances or environmental samples for their genotoxic or estrogenic potential is highly relevant for human- and environment-related risk assessment. To examine the effects on a mechanism-specific level, standardized cell-ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21839c354ae002eb076ccfb5ec23fa44
https://publica.fraunhofer.de/handle/publica/437578
https://publica.fraunhofer.de/handle/publica/437578
Autor:
Bastian Niklas Hölzel, Petra Stahlschmidt-Allner, Henner Hollert, Kurt Pfannkuche, Alexander Froschauer, Michael Schaffeld, Julia Brendt, Andreas Schiwy, Bernhard Allner, Daniel Derichsweiler, Jürgen Hescheler, Hans Thomas Allner
Publikováno v:
Archives of Toxicology
Archives of toxicology 94(9), 3265-3280 (2020). doi:10.1007/s00204-020-02821-3
Archives of toxicology 94(9), 3265-3280 (2020). doi:10.1007/s00204-020-02821-3
Archives of toxicology 94(9), 3265-3280 (2020). doi:10.1007/s00204-020-02821-3
Published by Springer, Berlin ; Heidelberg
Published by Springer, Berlin ; Heidelberg
Publikováno v:
Chemosphere, 295:133863, 1-11. Elsevier Limited
Haigis, A-C, Ottermanns, R, Schiwy, A, Hollert, H & Legradi, J 2022, ' Getting more out of the zebrafish light dark transition test ', Chemosphere, vol. 295, 133863, pp. 1-11 . https://doi.org/10.1016/j.chemosphere.2022.133863
Chemosphere : chemistry, biology and toxicology as related to environmental problems 295, 133863 (2022). doi:10.1016/j.chemosphere.2022.133863
Haigis, A-C, Ottermanns, R, Schiwy, A, Hollert, H & Legradi, J 2022, ' Getting more out of the zebrafish light dark transition test ', Chemosphere, vol. 295, 133863, pp. 1-11 . https://doi.org/10.1016/j.chemosphere.2022.133863
Chemosphere : chemistry, biology and toxicology as related to environmental problems 295, 133863 (2022). doi:10.1016/j.chemosphere.2022.133863
Chemosphere : chemistry, biology and toxicology as related to environmental problems 295, 133863 (2022). doi:10.1016/j.chemosphere.2022.133863
Published by Elsevier Science, Amsterdam [u.a.]
Published by Elsevier Science, Amsterdam [u.a.]
Autor:
Rita Schlichting, Maria König, Beate I. Escher, Beat Thalmann, Luise Henneberger, Lisa Glauch, Ying Shao, Hongxia Xiao, Henner Hollert, Andreas Schiwy, Marie Mühlenbrink
Publikováno v:
The Science of the total environment. 749
Many environmental pollutants pose a toxicological hazard only after metabolic activation. In vitro bioassays using cell lines or bacteria have often no or reduced metabolic activity, which impedes their use in the risk assessment. To improve the pre
Autor:
Kira Kauffmann, Henner Hollert, Julia Brendt, Lisa Gremm, Jochen Büchs, Andreas Schiwy, Kerstin Bluhm
Publikováno v:
The Science of the total environment. 726
The Ames test is the most commonly used mutagenicity test worldwide. It is based on a microbial system that uses histidine auxotrophic Salmonella typhimurium strains. Due to either spontaneous mutations or mutations induced by a mutagenic compound, t
Autor:
Andreas Schiwy, Julia Brendt, Mirna Velki, Hongxia Xiao, Beat Thalmann, Sarah E. Crawford, Henner Hollert
Publikováno v:
Science of The Total Environment. 759:143522
Metabolism has to be considered during the toxicological assessment of chemical and environmental samples because it is an important process in the mammalian liver. It can be assessed in vitro via liver homogenates called S9-fractions, an external me
Autor:
Hongxia Xiao, Henner Hollert, Julia Brendt, Sarah E. Crawford, Beat Thalmann, Mirna Velki, Carina Lackmann, Sebastian Heger, Andreas Schiwy
Publikováno v:
Science of The Total Environment. 751:142269
This study presents a high-throughput (HTP) micronucleus assay in multi-well plates with an automated evaluation for risk assessment applications. The evaluation of genotoxicity via the micronucleus assays according to international guidelines ISO 21
Autor:
Andreas Schiwy, Jochen Büchs, Felix Werner, Kira Kauffmann, Henner Hollert, Julia Brendt, Alexander Deitert, Julian Finklenburg
Publikováno v:
Science of The Total Environment. 717:137168
The Ames test is one of the most widely used mutagenicity tests. It employs histidine auxotrophic bacteria, which can mutate back to histidine prototrophy and, thus, grow on a histidine deficient medium. These mutants develop predominantly after addi
Autor:
Thomas-Benjamin Seiler, Markus Brinkmann, Leonie Nüßer, Beat Thalmann, Andreas Schiwy, Henner Hollert, Kathrin Eichbaum, Brigitte Thoms, Gabriele Guder, Ines Thiem, Kerstin Winkens, Sebastian Buchinger, Georg Reifferscheid
Publikováno v:
Nature Protocols. 10:1728-1741
This protocol describes a quantitative and robust 96-well-plate-reader-based assay for the measurement of ethoxyresorufin-O-deethylase (EROD) activity using the rat hepatoma cell line H4IIE. The assay can be used to determine the cytochrome P450 subf