Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Andreas S, Biebricher"'
Autor:
Giulia Bergamaschi, Kees-Karel H. Taris, Andreas S. Biebricher, Xamanie M. R. Seymonson, Hannes Witt, Erwin J. G. Peterman, Gijs J. L. Wuite
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract In the context of soft matter and cellular mechanics, microrheology - the use of micron-sized particles to probe the frequency-dependent viscoelastic response of materials – is widely used to shed light onto the mechanics and dynamics of m
Externí odkaz:
https://doaj.org/article/c22a827d38e146d699f5b30474cba1d6
Autor:
Giulia Bergamaschi, Andreas S. Biebricher, Hannes Witt, Fitzroy J. Byfield, Xamanie M.R. Seymonson, Cornelis Storm, Paul A. Janmey, Gijs J.L. Wuite
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114852- (2024)
Summary: A quantitative description of nuclear mechanics is crucial for understanding its role in force sensing within eukaryotic cells. Recent studies indicate that the chromatin within the nucleus cannot be treated as a homogeneous material. To elu
Externí odkaz:
https://doaj.org/article/c43b8da926274a51a423a10f299ad7d2
Autor:
Dian Spakman, Tinka V. M. Clement, Andreas S. Biebricher, Graeme A. King, Manika I. Singh, Ian D. Hickson, Erwin J. G. Peterman, Gijs J. L. Wuite
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
In anaphase, any unresolved DNA entanglements between the segregating sister chromatids can give rise to chromatin bridges. Here, the authors present an in vitro single-molecule assay that mimics chromatin under tension, to show that PICH is a tensio
Externí odkaz:
https://doaj.org/article/a446e33a0b39439f9380f36b5bf5fe55
Autor:
Julia A. M. Bakx, Andreas S. Biebricher, Graeme A. King, Panagiotis Christodoulis, Kata Sarlós, Anna H. Bizard, Ian D. Hickson, Gijs J. L. Wuite, Erwin J. G. Peterman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Here the authors probe the cleavage and gate opening of single-stranded DNA by the human topoisomerase TRR using a unique single-molecule strategy to reveal structural plasticity in response to both double-stranded DNA and the helicase BLM.
Externí odkaz:
https://doaj.org/article/764b1c9c1010460d8e514df34cefdef4
Autor:
Koen Schakenraad, Andreas S. Biebricher, Maarten Sebregts, Brian ten Bensel, Erwin J. G. Peterman, Gijs J. L. Wuite, Iddo Heller, Cornelis Storm, Paul van der Schoot
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
The mechanics and structural transitions of DNA are important to many essential processes inside living cells. Here the authors combine theory and single-molecule experiments to show that intercalator binding stabilises a new structural state of DNA:
Externí odkaz:
https://doaj.org/article/19651989c29f4b8187a2b287c64a0905
Autor:
Vadim Bogatyr, Andreas S. Biebricher, Giulia Bergamaschi, Erwin J.G. Peterman, Gijs J.L. Wuite
Publikováno v:
Bogatyr, V, Biebricher, A S, Bergamaschi, G, Peterman, E J G & Wuite, G J L 2023, ' Contact-free high-throughput measurements of living cell mechanics using quantitative acoustophoresis ', Biophysical Journal, vol. 122, no. 3 Supplement 1, pp. 325a-325a . https://doi.org/10.1016/j.bpj.2022.11.1815
Biophysical Journal, 122(3 Supplement 1), 325a-325a. Biophysical Society
Biophysical Journal, 122(3 Supplement 1), 325a-325a. Biophysical Society
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66bb3f6668bd1e7d02224d1ce642d24
https://hdl.handle.net/1871.1/520e8e1f-e7b1-41b0-a067-efb43c4d4d38
https://hdl.handle.net/1871.1/520e8e1f-e7b1-41b0-a067-efb43c4d4d38
Autor:
Xamanie M.R. Seymonson, Panagiotis Christodoulis, Mandy Erkelens, Andreas S. Biebricher, Remus T. Dame, Gijs J.L. Wuite
Publikováno v:
Biophysical Journal. 122:72a-73a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc1adfc274ab58db087b140785c85c98
https://doi.org/10.1016/j.bpj.2022.11.598
https://doi.org/10.1016/j.bpj.2022.11.598
Autor:
Adam S. Backer, Jack W Shepherd, Iddo Heller, Graeme A. King, Mark C. Leake, Agnes Noy, Erwin J.G. Peterman, Andreas S. Biebricher, Gijs J.L. Wuite
Publikováno v:
The Journal of Physical Chemistry. B
Journal of Physical Chemistry B, 125(30), 8351-8361. American Chemical Society
The Journal of Physical Chemistry
Backer, A S, King, G A, Biebricher, A S, Shepherd, J W, Noy, A, Leake, M C, Heller, I, Wuite, G J L & Peterman, E J G 2021, ' Elucidating the Role of Topological Constraint on the Structure of Overstretched DNA Using Fluorescence Polarization Microscopy ', Journal of Physical Chemistry B, vol. 125, no. 30, pp. 8351-8361 . https://doi.org/10.1021/acs.jpcb.1c02708
Journal of Physical Chemistry B, 125(30), 8351-8361. American Chemical Society
The Journal of Physical Chemistry
Backer, A S, King, G A, Biebricher, A S, Shepherd, J W, Noy, A, Leake, M C, Heller, I, Wuite, G J L & Peterman, E J G 2021, ' Elucidating the Role of Topological Constraint on the Structure of Overstretched DNA Using Fluorescence Polarization Microscopy ', Journal of Physical Chemistry B, vol. 125, no. 30, pp. 8351-8361 . https://doi.org/10.1021/acs.jpcb.1c02708
The combination of DNA force spectroscopy and polarization microscopy of fluorescent DNA intercalator dyes can provide valuable insights into the structure of DNA under tension. These techniques have previously been used to characterize S-DNA - an el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12a9fe28b567a6fb6bb03315b05d8a6
http://europepmc.org/articles/PMC8350907
http://europepmc.org/articles/PMC8350907
Autor:
Andreas S. Biebricher, Gijs J.L. Wuite, Graeme A. King, Dian Spakman, Erwin J.G. Peterman, Julia A M Bakx
Publikováno v:
Nucleic Acids Research
Spakman, D, Bakx, J A M, Biebricher, A S, Peterman, E J G, Wuite, G J L & King, G A 2021, ' Unravelling the mechanisms of Type 1A topoisomerases using single-molecule approaches ', Nucleic acids research, vol. 49, no. 10, pp. 5470-5492 . https://doi.org/10.1093/nar/gkab239
Spakman, D, Bakx, J A M, Biebricher, A S, Peterman, E J G, Wuite, G J L & King, G A 2021, ' Unravelling the mechanisms of Type 1A topoisomerases using single-molecule approaches ', Nucleic acids research, vol. 49, no. 10, pp. 5470-5492 . https://doi.org/10.1093/nar/gkab239
Topoisomerases are essential enzymes that regulate DNA topology. Type 1A family topoisomerases are found in nearly all living organisms and are unique in that they require single-stranded (ss)DNA for activity. These enzymes are vital for maintaining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0c475cf9cf649e394fdabf2cef2ebe
http://europepmc.org/articles/PMC8191776
http://europepmc.org/articles/PMC8191776
Autor:
Dian Spakman, Tinka V.M. Clement, Andreas S. Biebricher, Graeme A. King, Manika I. Singh, Ian D. Hickson, Erwin J.G. Peterman, Gijs J.L. Wuite
Publikováno v:
Biophysical Journal. 122:72a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c23511b05ed54aa0c59be2eec2fc7aad
https://doi.org/10.1016/j.bpj.2022.11.594
https://doi.org/10.1016/j.bpj.2022.11.594