Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Andreas Rohwer"'
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Akademický článek
A comparative chemogenomics strategy to predict potential drug targets in the metazoan pathogen, Schistosoma mansoni.
Autor: Conor R Caffrey, Andreas Rohwer, Frank Oellien, Richard J Marhöfer, Simon Braschi, Guilherme Oliveira, James H McKerrow, Paul M Selzer
Publikováno v: PLoS ONE, Vol 4, Iss 2, p e4413 (2009)
Schistosomiasis is a prevalent and chronic helmintic disease in tropical regions. Treatment and control relies on chemotherapy with just one drug, praziquantel and this reliance is of concern should clinically relevant drug resistance emerge and spre
Externí odkaz: https://doaj.org/article/6f89ee6c78bd429a904d5fb89455d660
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4
Glutamate decarboxylase of the parasitic arthropods Ctenocephalides felis and Rhipicephalus microplus: Gene identification, cloning, expression, assay development, identification of inhibitors by high throughput screening and comparison with the orthologs from Drosophila melanogaster and mouse
Autor: Andreas Rohwer, Michael Gaßel, Michael Berger, Thomas Ilg, Sandra Noack
Publikováno v: Insect Biochemistry and Molecular Biology. 43:162-177
Glutamate decarboxylase (l-glutamate 1-carboxylyase, E.C. 4.1.1.15, GAD) is the rate-limiting enzyme for the production of γ-aminobutyric acid (GABA), the major inhibitory neurotransmitter in vertebrates and invertebrates. We report the identificati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0dd297f51a056a1e1d1e009a9e7f287
https://doi.org/10.1016/j.ibmb.2012.11.001
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6
Identification and characterisation of the dopamine receptor II from the cat flea Ctenocephalides felis (CfDopRII)
Autor: Ellen I. Closs, Didier Rognan, Christian Wolf, Andreas Rohwer, Andreas Krasky, Sonja Gerber, Nikolas Gunkel, Simone Lindauer, Paul Selzer
Publikováno v: Insect Biochemistry and Molecular Biology
Insect Biochemistry and Molecular Biology, Elsevier, 2006, 36, pp.749-758
Insect Biochemistry and Molecular Biology, Elsevier, 2006, 36 (10), pp.749-758. ⟨10.1016/j.ibmb.2006.07.003⟩
International audience; G protein-coupled receptors (GPCRs) represent a protein family with a wide range of functions. Approximately 30% of human drug targets are GPCRs, illustrating their pharmaceutical relevance. In contrast, the knowledge about in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b023358c62a10f88faebe693aade7a30
https://doi.org/10.1016/j.ibmb.2006.07.003
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8
DIK, a Novel Protein Kinase That Interacts with Protein Kinase Cδ
Autor: Andreas Rohwer, Gabriele Rincke, Luise Stempka, Corinna Bähr, Michael Gschwendt, Friedrich Marks
Publikováno v: Journal of Biological Chemistry. 275:36350-36357
A novel serine/threonine kinase, termed DIK, was cloned using the yeast two-hybrid system to screen a cDNA library from the human keratinocyte cell line HaCaT with the catalytic domain of rat protein kinase Cδ (PKCδcat) cDNA as bait. The predicted
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::afbce4be9f297aa647364720cc44fd6d
https://doi.org/10.1074/jbc.m004771200
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9
Cloning, expression and characterization of an A6-related protein
Autor: Michael Gschwendt, Andreas Rohwer, Walter Kittstein, Friedrich Marks
Publikováno v: European Journal of Biochemistry. 263:518-525
By interaction cloning (yeast two-hybrid system) using the catalytic domain of protein kinase Czeta (PKCzeta) as bait, we cloned a human full-length cDNA with 62% nucleotide homology to the A6 protein recently cloned and characterized by Beeler et al
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93edeee94ec4c62492fc56476414abdc
https://doi.org/10.1046/j.1432-1327.1999.00537.x
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